CAS No.: 1308631-40-4
NDMC101 Catalog No. CSN27234
Synonyms: HS-Cm
NDMC101 is a potent osteoclastogenesis inhibitor and inhibits osteoclast differentiation via down-regulation of NFATc1-modulated gene express. NDMC101 is similar to the DPP4 substrate and is a significant inhibitor of early T-cell activation via DPP4 inhibition. NDMC101can be used for study of bone disorders, such as rheumatoid arthritis, and synovial inflammation et al .
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 参考文献
- [1] Chia-Pi Cheng, et al. A benzamide-linked small molecule NDMC101 inhibits NFATc1 and NF-κB activity: a potential osteoclastogenesis inhibitor for experimental arthritis. J Clin Immunol. 2012 Aug;32(4):762-77.
- [2] Jun-Ting Liou, et al. A salicylate-based small molecule HS-Cm exhibits immunomodulatory effects and inhibits dipeptidyl peptidase-IV activity in human T cells. Eur J Pharmacol. 2014 Mar 5;726:124-32.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1308631-40-4 | 储存条件 |
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| 分子式 | C13H9ClFNO2 | 运输 | 蓝冰 | |
| 分子量 | 265.67 | 别名 | HS-Cm |
