CAS No.: 1253584-84-7
NMS-E973 Catalog No. CSN16765
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of < 10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Fogliatto G, Gianellini L, et al. NMS-E973, a novel synthetic inhibitor of Hsp90 with activity against multiple models of drug resistance to targeted agents, including intracranial metastases. Clin Cancer Res. 2013 Jul 1;19(13):3520-32.
- [2] Brasca MG, Mantegani S, et al. Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90). Bioorg Med Chem. 2013 Nov 15;21(22):7047-63.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1253584-84-7 | 储存条件 |
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| 分子式 | C22H22N4O7 | 运输 | 蓝冰 | |
| 分子量 | 454.43 | 别名 |
