CAS No.: 155683-00-4
Notoginsenoside Ft1/三七皂苷FT1 Catalog No. CSN15253
Synonyms: 三七皂苷FT1
Notoginsenoside Ft1, a natural saponin isolated and purified from the roots of Panax notoginseng, may accelerate diabetic wound healing by orchestrating multiple processes, including promoting fibroblast proliferation, enhancing angiogenesis, and attenuating inflammatory response, which provided a great potential application of it in clinics for patients with diabetic foot ulcers, arrest the proliferation and elicited the apoptosis of SH-SY5Y cells possibly via p38 MAPK and ERK1/2 pathways, which indicates the potential therapeutic effect of it on human neuroblastoma, activate both glucocorticoid and estrogen receptors to induce endothelium-dependent, nitric oxide-mediated relaxations in rat mesenteric arteries, and enhance platelet aggregation by activating a signalling network mediated through P2Y12 receptors.
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400-920-2911
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生物活性
- 描述
- 参考文献
- [1] Zhang E, Gao B, et al. Notoginsenoside Ft1 Promotes Fibroblast Proliferation via PI3K/Akt/mTOR Signaling Pathway and Benefits Wound Healing in Genetically Diabetic Mice. J Pharmacol Exp Ther. 2016 Feb;356(2):324-32.
- [2] Gao B, Shi HL, et al. p38 MAPK and ERK1/2 pathways are involved in the pro-apoptotic effect of notoginsenoside Ft1 on human neuroblastoma SH-SY5Y cells. Life Sci. 2014 Jul 17;108(2):63-70.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 155683-00-4 | 储存条件 |
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| 分子式 | C47H80O17 | 运输 | 蓝冰 | |
| 分子量 | 917.13 | 别名 | 三七皂苷FT1 |
