CAS No.: 1261491-89-7
Olumacostat glasaretil Catalog No. CSN20332
Synonyms: OG;DRM-01-B;DRM01
Olumacostat glasaretil is an acetyl-CoA carboxylase inhibitor, and inhibits acetyl-coenzyme A carboxylase, which is responsible for the first, rate-limiting step in de novo fatty acid synthesis. Olumacostat glasaretil has been used in the treatment of acne vulgaris.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03028363 Acne Vulgaris Phase 3 Completed - - NCT02431052 Acne Vulgaris Phase 2 Completed - - NCT03073486 Acne Vulgaris Phase 3 Completed - - - 更多
- 参考文献
- [1] Melnik BC. Olumacostat Glasaretil, a Promising Topical Sebum-Suppressing Agent that Affects All Major Pathogenic Factors of Acne Vulgaris. J Invest Dermatol. 2017 Jul;137(7):1405-1408.
- [2] Hunt DW, Winters GC, et al. Inhibition of Sebum Production with the Acetyl Coenzyme A Carboxylase Inhibitor Olumacostat Glasaretil. J Invest Dermatol. 2017 Jul;137(7):1415-1423.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1261491-89-7 | 储存条件 |
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| 分子式 | C26H43NO7 | 运输 | 蓝冰 | |
| 分子量 | 481.62 | 别名 | OG;DRM-01-B;DRM01 |
