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CAS No.: 7240-38-2

Oxacillin Sodium/苯唑西林钠 Catalog No. CSN11624

Synonyms: Methicillin;苯唑西林钠一水合物;苯唑西林钠盐一水合物

Oxacillin Sodium Monohydrate is a narrow-spectrum penicillin β-lactam antibiotic.

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技术信息

生物活性

描述Oxacillin sodium monohydrate is an antibiotic similar to flucloxacillin used in resistant staphylococci infections. oxacillin is an additional penicillin that can cause interstitial nephritis^[2]. The potential exists for oxacillin 50 mg/mL to cause tissue damage in humans if an extravasation occurs^[3]. Moreover, abnormalities in liver function were associated with a daily oxacillin sodium dose of greater than or equal to 12 gm as well as with heroin addiction and staphylococcal endocarditis^[4]. The geometric means of the serum bactericidal activity after 1, 6, and 11 h were, respectively, 22, 17, and 9 after treatment with oxacillin plus rifampin and 25, 3. 4, and 2. 3 after treatment with oxacillin plus placebo. It was suggested that the addition of rifampin to oxacillin or vancomycin might only be beneficial to severely ill patients^[5].
参考文献

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.2653 mL
- 11.3267 mL
- 22.6535 mL
- 5 mM
- 0.4531 mL
- 2.2653 mL
- 4.5307 mL
- 10 mM
- 0.2265 mL
- 1.1327 mL
- 2.2653 mL

技术信息

CAS号

7240-38-2

储存条件

粉末: Inert atmosphere,2-8°C

液体: -20°C:3-6 月 -80°C:12月

分子式

C19H20N3NaO6S

运输

蓝冰

分子量

441.43

别名

Methicillin;苯唑西林钠一水合物;苯唑西林钠盐一水合物;新青霉素Ⅱ钠一水合物

溶解度

DMSO	50.0 mg/mL (113.3 mM)

动物实验配方

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