CAS No.: 269718-83-4
Pardoprunox HCl Catalog No. CSN18173
Synonyms: SLV-308 hydrochloride;DU-126891 hydrochloride;SLV-308 HCl
Pardoprunox HCl is a partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist, D2 (pKi = 8.1) and D3 receptor (pKi = 8.6) partial agonist and 5-HT1A receptor (pKi = 8.5) full agonist.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Glennon JC, Van Scharrenburg G, et al. In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl] -2(3H)-benzoxazolone, monohydrochloride): a novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist. Synapse. 2006 Dec 15;60(8):599-608.
- [2] Jones CA, Johnston LC, et al. An in vivo pharmacological evaluation of pardoprunox (SLV308)--a novel combined dopamine D(2)/D(3) receptor partial agonist and 5-HT(1A) receptor agonist with efficacy in experimental models of Parkinson's disease. Eur Neuropsychopharmacol. 2010 Aug;20(8):582-93.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 269718-83-4 | 储存条件 |
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| 分子式 | C12H16ClN3O2 | 运输 | 蓝冰 | |||||||
| 分子量 | 269.73 | 别名 | SLV-308 hydrochloride;DU-126891 hydrochloride;SLV-308 HCl;DU 126891 HCl;Pardoprunox (hydrochloride);DU-126891;SLV-308;SME-308;Pardoprunox;Pardoprunox HCl | |||||||
| 溶解度 |
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动物实验配方 |
