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CAS No.: 1215197-37-7
Synonyms: PF-4991532
PF-04991532 is a potent, hepatoselective glucokinase activator with EC50s of 80 and 100 nM in human and rat, respectively.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01369602 | Type 2 Diabetes Mellitus ... more >> Healthy Collapse << | Phase 1 | Completed | - | United States, California ... more >> Pfizer Investigational Site Anaheim, California, United States, 92801 United States, Florida Pfizer Investigational Site DeLand, Florida, United States, 32720 Collapse << |
NCT01338870 | Diabetes Mellitus, Type 2 | Phase 2 | Completed | - | - |
NCT01388829 | Healthy | Phase 1 | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 Collapse << |
实验方案
技术信息
CAS号 | 1215197-37-7 | 储存条件 |
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分子式 | C18H19F3N4O3 | 运输 | 蓝冰 | |
分子量 | 396.36 | 别名 | PF-4991532 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01369602 | Type 2 Diabetes Mellitus ... more >> Healthy Collapse << | Phase 1 | Completed | - | United States, California ... more >> Pfizer Investigational Site Anaheim, California, United States, 92801 United States, Florida Pfizer Investigational Site DeLand, Florida, United States, 32720 Collapse << |
NCT01338870 | Diabetes Mellitus, Type 2 | Phase 2 | Completed | - | - |
NCT01388829 | Healthy | Phase 1 | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 Collapse << |
NCT01469065 | Diabetes Mellitus, Type 2 | Phase 1 | Completed | - | United States, California ... more >> Pfizer Investigational Site Chula Vista, California, United States, 91911 United States, Florida Pfizer Investigational Site Miami, Florida, United States, 33169 Japan Pfizer Investigational Site Hachioji-shi, Tokyo, Japan Collapse << |
NCT01336738 | Diabetes, Type 2 | Phase 2 | Completed | - | - |
NCT01338870 | - | - | Completed | - | - |
NCT01469481 | Healthy | Phase 1 | Completed | - | United States, Washington ... more >> Pfizer Investigational Site Tacoma, Washington, United States, 98418 Collapse << |
NCT01336738 | - | - | Completed | - | - |
NCT01351129 | Healthy | Phase 1 | Completed | - | Singapore ... more >> Pfizer Investigational Site Singapore, Singapore, 188770 Collapse << |
NCT01369277 | Diabetes Mellitus ... more >> Diabetes Mellitus, Type 2 Glucose Metabolism Disorders Collapse << | Phase 1 | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 Collapse << |
NCT01102673 | Diabetes Mellitus ... more >> Diabetes Mellitus, Type 2 Glucose Metabolism Disorders Collapse << | Phase 1 | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511 Collapse << |
NCT01370343 | Healthy Drug ... more >>Interaction Collapse << | Phase 1 | Completed | - | Belgium ... more >> Pfizer Investigational Site Bruxelles, Belgium, B-1070 Collapse << |
NCT01469065 | - | - | Completed | - | - |
NCT01129258 | Diabetes Mellitus ... more >> Diabetes Mellitus, Type 2 Glucose Metabolism Disorders Collapse << | Phase 1 | Completed | - | United States, California ... more >> Pfizer Investigational Site Chula Vista, California, United States, 91911 Pfizer Investigational Site Fountain Valley, California, United States, 92708 United States, Florida Pfizer Investigational Site Miami, Florida, United States, 33169 United States, Texas Pfizer Investigational Site San Antonio, Texas, United States, 78229 Collapse << |
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