CAS No.: 845714-00-3
PHA-767491 Catalog No. CSN16230
Synonyms: CAY10572
PHA-767491 is a potent, ATP-competitive dual Cdc7/Cdk9 inhibitor with IC50 values of 10/34 nM, and also an inhibitor of NRF2.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Liu HY, Tuckett AZ, et al. Repurposing of the CDK inhibitor PHA-767491 as a NRF2 inhibitor drug candidate for cancer therapy via redox modulation. Invest New Drugs. 2018.
- [2] Natoni A, Murillo LS, et al. Mechanisms of action of a dual Cdc7/Cdk9 kinase inhibitor against quiescent and proliferating CLL cells. Mol Cancer Ther. 2011 Sep;10(9):1624-34.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 845714-00-3 | 储存条件 |
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| 分子式 | C12H11N3O | 运输 | 蓝冰 | |||||||||
| 分子量 | 213.24 | 别名 | CAY10572 | |||||||||
| 溶解度 |
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动物实验配方 |
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