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CAS No.: 131-69-1

Phthalylsulfacetamide/酞磺醋胺 Catalog No. CSN11708

Synonyms: Enterocid;Enteramide;Ftalicetimida

Phthalylsulfacetamide is a sulfonamide with a high solubility and suited for systemic use for diseases of the eye.

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技术信息

生物活性

描述Phthalylsulfacetamide is a sulfonamide antibiotic used for topical application to the skin and the conjunctiva. After oral administration, phthalylsulfacetamide slowly decompose in the intestine, and release sulfacetamide, generating antibacterial effect. Xylan increased both liver and fecal folate, and this effect was nearly eliminated by phthalylsulfacetamide. With the addition of phthalylsulfacetamide, liver folate increased in rats fed wheat bran diets and decreased in rats fed folic acid diets. Phthalylsulfacetamide had no effect on fecal folate excretion from rats fed the wheat bran diets^[2].
参考文献

[1] CHRISTIAN AB. Phthalylsulfacetamide as a treatment for infectious calf scours. J Am Vet Med Assoc. 1952 Sep;121(906):185-6.
[2] Keagy PM, Oace SM. Rat bioassay of wheat bran folate and effects of intestinal bacteria. J Nutr. 1989 Dec;119(12):1932-9. doi: 10.1093/jn/119.12.1932. PMID: 2559958.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.7597 mL
- 13.7985 mL
- 27.5971 mL
- 5 mM
- 0.5519 mL
- 2.7597 mL
- 5.5194 mL
- 10 mM
- 0.2760 mL
- 1.3799 mL
- 2.7597 mL

技术信息

CAS号

131-69-1

储存条件

粉末: Sealed in dry,Room Temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C16H14N2O6S

运输

蓝冰

分子量

362.36

别名

Enterocid;Enteramide;Ftalicetimida;Kalacet;NSC-163977;TSC-80;酞磺醋胺;邻苯二甲酰磺胺乙酰胺

溶解度

DMSO	50.0 mg/mL (138.0 mM) warming
Water	insoluble

动物实验配方

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