CAS No.: 1349796-36-6
PI3K-IN-1 Catalog No. CSN15908
Synonyms: XL-147 derivative 1;Voxtalisib Analogue;SAR245409 Analogue
XL765 analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM, and also inhibits DNA-PK and mTOR.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Prasad G, Sottero T, et al. Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. Neuro Oncol. 2011 Apr;13(4):384-92.
- [2] Garcia-Echeverria C, Sellers WR. Drug discovery approaches targeting the PI3K/Akt pathway in cancer. Oncogene. 2008 Sep 18;27(41):5511-26.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1349796-36-6 | 储存条件 |
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| 分子式 | C31H29N5O6S | 运输 | 蓝冰 | |||||||||
| 分子量 | 599.66 | 别名 | XL-147 derivative 1;Voxtalisib Analogue;SAR245409 Analogue;XL147 analog 2;Voxtalisib-Analog;XL765-Analog;SAR245409-Analog | |||||||||
| 溶解度 |
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动物实验配方 |
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