CAS No.: 60477-34-1
Pifithrin-β Catalog No. CSN18356
Synonyms: PFT β;Cyclic Pifithrin-α;Cyclic Pifithrin-alpha
Pifithrin-β is a potent p53 inhibitor with IC50 of 23 μM in an antiproliferative assay in the human ovarian carcinoma cell line, IGROV-1.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Christodoulou MS, Colombo F, et al. Synthesis and biological evaluation of imidazolo[2,1-b] benzothiazole derivatives, as potential p53 inhibitors. Bioorg Med Chem. 2011 Mar 1;19(5):1649-57.
- [2] Fernandez-Cruz ML, Valdehita A, et al. Biological and chemical studies on aryl hydrocarbon receptor induction by the p53 inhibitor pifithrin-α and its condensation product pifithrin-β. Life Sci. 2011 Apr 25;88(17-18):774-83.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 60477-34-1 | 储存条件 |
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| 分子式 | C16H16N2S | 运输 | 蓝冰 | |
| 分子量 | 268.38 | 别名 | PFT β;Cyclic Pifithrin-α;Cyclic Pifithrin-alpha;Pifithrin-beta |
