CAS No.: 937039-45-7
Pimelic Diphenylamide 106 Catalog No. CSN16486
Synonyms: RGFA-8;TC-H 106;Histone Deacetylase Inhibitor VII
Pimelic diphenylamide 106 is an inhibitor of class I HDAC with IC50 for HDAC1, HDAC2, and HDAC3 of 150 nM, 760nM, and 370 nM, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Xu C, Soragni E, et al. Chemical probes identify a role for histone deacetylase 3 in Friedreich's ataxia gene silencing. Chem Biol. 2009 Sep 25;16(9):980-9.
- [2] Chou CJ, Herman D, et al. Pimelic diphenylamide 106 is a slow, tight-binding inhibitor of class I histone deacetylases. J Biol Chem. 2008 Dec 19;283(51):35402-9.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 937039-45-7 | 储存条件 |
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| 分子式 | C20H25N3O2 | 运输 | 蓝冰 | |||||
| 分子量 | 339.43 | 别名 | RGFA-8;TC-H 106;Histone Deacetylase Inhibitor VII | |||||
| 溶解度 |
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动物实验配方 |
