CAS No.: 54-91-1
Pipobroman/哌泊溴烷 Catalog No. CSN11732
Synonyms: PB;Vercyte;NSC25154
Pipobroman is an anti-cancer drug that probably acts as an alkylating agent.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01243944 Polycythemia Vera Phase 3 Completed - - NCT02038036 Polycythemia Vera Phase 3 Active, not recruiting April 8, 2020 - NCT01243944 - - Completed - - - 参考文献
- [1] Kiladjian JJ, Chevret S, et al. Treatment of polycythemia vera with hydroxyurea and pipobroman: final results of a randomized trial initiated in 1980. J Clin Oncol. 2011 Oct 10;29(29):3907-13.
- [2] Passamonti F, Lazzarino M. Treatment of polycythemia vera and essential thrombocythemia: the role of pipobroman. Leuk Lymphoma. 2003 Sep;44(9):1483-8.
- [3] Cassius C, Pages C, Roux J, Lhote R, Lavocat R, Réa D, Bagot M, Mourah S, Battistella M, Lebbé C, Dumaz N. Association of Vemurafenib and Pipobroman Enhances BRAF-CRAF Dimerization in Squamous Cell Carcinoma. J Invest Dermatol. 2016 Jun;136(6):1302-1305
- [4] Passamonti F, Malabarba L, Orlandi E, Pascutto C, Brusamolino E, Astori C, Baratè C, Canevari A, Corso A, Bernasconi P, Cazzola M, Lazzarino M. Pipobroman is safe and effective treatment for patients with essential thrombocythaemia at high risk of thrombosis. Br J Haematol. 2002 Mar;116(4):855-61
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 54-91-1 | 储存条件 |
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| 分子式 | C10H16Br2N2O2 | 运输 | 蓝冰 | |
| 分子量 | 356.05 | 别名 | PB;Vercyte;NSC25154;Trade names Vercite Vercyte;哌泊溴烷 |
