CAS No.: 66663-91-0
Polygalacin D/远志皂苷D Catalog No. CSN19927
Polygalacin D, a natural product isolated and purified from the roots of Polygala tenuifolia Willd, can inhibit the expression of lipopolysaccharide (LPS)-induced iNOS and COX-2 protein and mRNA without an appreciable cytotoxic effect on RAW 264.7 macrophages, suppress induction by LPS of pro-inflammatory cytokines such as prostaglandin E2 (PGE2), exhibit significant inhibition on the proliferation of five kinds of cultured human tumor cell lines, i.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Zhan Q, Zhang F, et al. Two new oleanane-type triterpenoids from Platycodi Radix and anti-proliferative activity in HSC-T6 cells. Molecules. 2012 Dec 13;17(12):14899-907.
- [2] Ahn KS, Noh EJ, et al. Inhibition of inducible nitric oxide synthase and cyclooxygenase II by Platycodon grandiflorum saponins via suppression of nuclear factor-kappaB activation in RAW 264.7 cells. Life Sci. 2005 Apr 1;76(20):2315-28.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 66663-91-0 | 储存条件 |
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| 分子式 | C57H92O27 | 运输 | 蓝冰 | |
| 分子量 | 1209.32 | 别名 |
