CAS No.: 51-15-0
Pralidoxime chloride/氯磷啶 Catalog No. CSN17059
Synonyms: 2-PAM chloride;2-PAM(Chloride);Pralidoxime (chloride)
Pralidoxime chloride is an AChE reactivator, used as an antidote to organophosphate pesticides and chemicals.
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纯度 & 质量文件
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靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00333944 Acute Organophosphorus Pestici... more >>de Poisoning Collapse << Not Applicable Completed - India ... more >> Giriraj Hospital and Intensive Care Unit. Baramati. Pune District., Maharashtra., India, 413 102. Collapse << NCT02160548 Organophosphate Poisoning Phase 3 Completed - Bangladesh ... more >> Sylhet M.A.G.Osmani Medical College Hospital Sylhet, Bangladesh, 3100 Collapse << NCT02040350 Deaths Phase 1 Completed - India ... more >> Sheri kashmir insititute of medical sciences Srinagar, Srinagar Kashmir, India, 190006 Collapse << - 更多
- 参考文献
- [1] Lucyk S, Vilensky D, et al. Reactivation of plasma butyrylcholinesterase by pralidoxime chloride in patients poisoned by WHO class II toxicity organophosphorus insecticides. Toxicol Sci. 2014 Apr;138(2):482.
- [2] Rios JC, Repetto G, et al. High concentrations of pralidoxime are needed for the adequate reactivation of human erythrocyte acetylcholinesterase inhibited by dimethoate in vitro. Toxicol In Vitro. 2005 Oct;19(7):893-7.
- [3] Konickx LA, Worek F, Jayamanne S, Thiermann H, Buckley NA, Eddleston M. Reactivation of plasma butyrylcholinesterase by pralidoxime chloride in patients poisoned by WHO class II toxicity organophosphorus insecticides. Toxicol Sci. 2013 Dec;136(2):274-83.
- [4] Brittain MK, McGarry KG, Moyer RA, Babin MC, Jett DA, Platoff GE Jr, Yeung DT. Efficacy of Recommended Prehospital Human Equivalent Doses of Atropine and Pralidoxime Against the Toxic Effects of Carbamate Poisoning in the Hartley Guinea Pig. Int J Toxicol. 2016 May;35(3):344-57.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 51-15-0 | 储存条件 |
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| 分子式 | C7H9ClN2O | 运输 | 蓝冰 | |||||
| 分子量 | 172.61 | 别名 | 2-PAM chloride;2-PAM(Chloride);Pralidoxime (chloride);2-PAM;Pralidoxime Chloride;Pralidoxime;Pralidoxine chloride;ComboPen;Protopam chloride;14C-labeled;pralidoxime methyl sulfate;pralidoxime nitrate (1:1) | |||||
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动物实验配方 |
