CAS No.: 1180676-32-7
PS-48 Catalog No. CSN17521
Synonyms: PS48
PS48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator with Kd value of 10.3 μM and binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Spate LD, Brown A, et al. PS48 can replace bovine serum albumin in pig embryo culture medium, and improve in vitro embryo development by phosphorylating AKT. Mol Reprod Dev. 2015 Apr;82(4):315-20.
- [2] Hindie V, Stroba A, et al. Structure and allosteric effects of low-molecular-weight activators on the protein kinase PDK1. Nat Chem Biol. 2009 Oct;5(10):758-64.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1180676-32-7 | 储存条件 |
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| 分子式 | C17H15ClO2 | 运输 | 蓝冰 | |||||||
| 分子量 | 286.75 | 别名 | PS48 | |||||||
| 溶解度 |
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动物实验配方 |
