CAS No.: 1315323-00-2
Pyr10 Catalog No. CSN17688
Pyr 10 is a TRPC3-selective inhibitor. IC50 of Ca2+ influx inhibition by Pyr10 in carbachol-stimulated YFP-TRPC3-transfected HEK293 cells for ROCE and thapsigargin-depleted native RBL-2H3 cells for SOCE is 0.72 uM and 13.08 uM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Schleifer H, Doleschal B, et al. Novel pyrazole compounds for pharmacological discrimination between receptor-operated and store-operated Ca(2+) entry pathways. Br J Pharmacol. 2012 Dec;167(8):1712-22.
- [2] Obermayer D, Glasnov TN, et al. Microwave-assisted and continuous flow multistep synthesis of 4-(pyrazol-1-yl)carboxanilides. J Org Chem. 2011 Aug 19;76(16):6657-69.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1315323-00-2 | 储存条件 |
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| 分子式 | C18H13F6N3O2S | 运输 | 蓝冰 | |||||||||||||||
| 分子量 | 449.37 | 别名 | ||||||||||||||||
| 溶解度 |
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动物实验配方 |
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