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CAS No.: 161735-79-1
Synonyms: (R)-AGN1135 mesylate;TVP1012 mesylate;TVP-1012
Rasagiline Mesylate is an irreversible and selective MAO-B inhibitor used in early Parkinson's disease.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01280123 | Parkinson's Disease | Phase 2 | Completed | - | - |
NCT01280123 | - | - | Completed | - | - |
NCT01155466 | Parkinson Disease | Phase 3 | Completed | - | - |
实验方案
技术信息
CAS号 | 161735-79-1 | 储存条件 |
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分子式 | C13H17NO3S | 运输 | 蓝冰 | |||||
分子量 | 267.34 | 别名 | (R)-AGN1135 mesylate;TVP1012 mesylate;TVP-1012;Rasagiline Mesylate;Azilect;Rasagiline mesilate;Agilect;TVP-1022;TVP-101;AGN-1135;N-2-propynyl-1-indanamine N-propargyl-1-aminoindan mesylate;rasagiline;rasagiline hydrochloride;甲磺酸雷沙吉兰 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT01280123 | Parkinson's Disease | Phase 2 | Completed | - | - |
NCT01280123 | - | - | Completed | - | - |
NCT01155466 | Parkinson Disease | Phase 3 | Completed | - | - |
NCT01155479 | Parkinson Disease | Phase 3 | Terminated(Termininated for bu... more >>siness reasons) Collapse << | - | - |
NCT02696512 | Brain Injury | Phase 1 Phase 2 | Unknown | April 2017 | United States, New Jersey ... more >> International Brain Research Foundation Recruiting Edison, New Jersey, United States, 08837 Contact: Philip Defina, PhD 732-494-7600 pdefina@ibrfinc.org Principal Investigator: Philip Defina, PhD Collapse << |
NCT01155466 | - | - | Completed | - | - |
NCT03329508 | Parkinson Disease | Phase 3 | Recruiting | December 30, 2019 | - |
NCT01155479 | - | - | Terminated(Termininated for bu... more >>siness reasons) Collapse << | - | - |
NCT01215227 | Parkinson Disease ... more >> Idiopathic Parkinson Disease Collapse << | Phase 3 | Terminated | - | - |
NCT01098396 | - | - | Unknown | - | - |
NCT00203125 | Parkinson's Disease | Phase 3 | Completed | - | - |
NCT01968460 | Parkinson's Disease | Phase 2 Phase 3 | Completed | - | - |
NCT02789020 | Parkinson's Disease | Phase 2 | Recruiting | December 2020 | United States, Florida ... more >> Laboratory for Rehabilitation Neuroscience Recruiting Gainesville, Florida, United States, 32611 Contact: Nieci Black 352-294-1771 nblack@ufl.edu Collapse << |
NCT00902941 | Parkinson´s Disease | Phase 4 | Completed | - | Germany ... more >> University of Dresden Medical School, Smell & Taste Centre, Dept. of Neurology Dresden, Germany, 01307 Collapse << |
NCT01215227 | - | - | Terminated | - | - |
NCT01532128 | Parkinson Disease | Phase 1 | Completed | - | France ... more >> BIOTRIAL Rennes, France, F-35000 Collapse << |
NCT02207387 | Parkinson's Disease | Not Applicable | Unknown | March 2017 | Canada, British Columbia ... more >> Pacific Parkinson's Research Centre Recruiting Vancouver, British Columbia, Canada, V6P 2Z9 Principal Investigator: Martin J McKeown, MD Collapse << |
NCT00203060 | Parkinson's Disease | Phase 3 | Completed | - | - |
NCT01048229 | Early-stage Parkinson's Diseas... more >>e Collapse << | Phase 4 | Terminated(recruitment) | - | - |
NCT00492336 | Schizophrenia | Phase 4 | Completed | - | United States, Maryland ... more >> Baltimore VA Medical Center Baltimore, Maryland, United States, 21201 Keypoint Mental health Center Catonsville, Maryland, United States, 21228 Maryland Psychiatric REsearch Center Catonsville, Maryland, United States, 21228 Mosaic Community Mental health Center Catonsville, Maryland, United States, 21228 Keypoint Mental health Center Dundalk, Maryland, United States, 21222 Collapse << |
NCT00104273 | Dementia Alzh... more >>eimer's Disease Collapse << | Phase 2 | Completed | - | - |
NCT00492336 | - | - | Completed | - | - |
NCT00256204 | Parkinson's Disease | Phase 3 | Completed | - | - |
NCT00256204 | - | - | Completed | - | - |
NCT00203034 | Parkinson's Disease | Phase 3 | Completed | - | United States, Illinois ... more >> Rush - Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, New York Columbia - Presbyterian Medical Center New York, New York, United States, 10032 University of Rochester Rochester, New York, United States, 14642 United States, Texas Baylor College of Medicine Houston, Texas, United States, 77030 Collapse << |
NCT02359552 | Alzheimer's Disease | Phase 2 | Active, not recruiting | February 15, 2019 | United States, Nevada ... more >> Cleveland Clinic Lou Ruvo Center for Brain Health Las Vegas, Nevada, United States, 89106 United States, Ohio Cleveland Clinic Main Campus Cleveland, Ohio, United States, 44195 Cleveland Clinic Lakewood Hospital Lakewood, Ohio, United States, 44107 Collapse << |
NCT02068625 | Retinal Detachment | Phase 4 | Active, not recruiting | December 31, 2018 | Switzerland ... more >> Department of Ophthalmology, Bern University Hospital Bern, Switzerland, 3010 Collapse << |
NCT01382342 | Parkinson's Disease | Phase 4 | Completed | - | United States, Rhode Island ... more >> Butler Hospital Providence, Rhode Island, United States, 02906 Collapse << |
NCT01765257 | Drug-naïve Patients With Parki... more >>nson's Disease Apathy Collapse << | Phase 4 | Unknown | March 2015 | France ... more >> CHU Clermont-Ferrand Not yet recruiting Clermont-Ferrand, France, 63003 Contact: Patrick LACARIN 04 73 75 11 95 placarin@chu-clermontferrand.fr Collapse << |
NCT01049984 | Parkinson's Disease | Phase 4 | Completed | - | - |
NCT00203138 | Parkinson's Disease | Phase 3 | Completed | - | - |
NCT01532128 | - | - | Completed | - | - |
NCT01055379 | Depressive Symptoms ... more >> Parkinson's Disease Collapse << | Phase 4 | Completed | - | Italy ... more >> IT010 Cagliari, Italy, 9134 IT007 Chieti, Italy, 66013 IT004 Genova, Italy, 16132 IT005 Lido di Camaiore, Italy, 55043 IT003 Messina, Italy, 98122 IT012 Milano, Italy, 20135 IT001 Naples, Italy, 80131 IT011 Roma, Italy, 161 IT008 Rome, Italy, 133 IT015 Torino, Italy, 10126 IT013 Venezia, Italy, 30126 IT009 Verona, Italy, 37134 Collapse << |
NCT02278588 | - | - | Unknown | December 2016 | United States, New York ... more >> University at Buffalo Buffalo, New York, United States, 14214 Collapse << |
NCT01187888 | Progressive Supranuclear Palsy | Phase 3 | Terminated(IMP used off label ... more >>by phys. in pat. with PSP. Thus no more eligible patients were available for the study(pre-treatm.with Rasagiline=exclusion criterion) Collapse << | - | Germany ... more >> Department of Neurology and Palliative Care Klinikum der Universität München (Hospital of the University of Munich) München, Germany, 81377 Collapse << |
NCT01385735 | Parkinson Disease | Phase 4 | Unknown | April 2013 | Germany ... more >> St. Josef Hospital Not yet recruiting Bochum, Nordrhein-Westfalen, Germany, 44791 Principal Investigator: Dirk Woitalla, MD Sub-Investigator: Irene Daum, Prof. Collapse << |
NCT01049984 | - | - | Completed | - | - |
NCT00955604 | - | - | Completed | - | - |
NCT01268891 | Parkinson's Disease | Phase 3 | Completed | - | - |
NCT00696215 | Parkinson's Disease | Phase 4 | Unknown | October 2008 | Turkey ... more >> Marmara University Recruiting Istanbul, Turkey Contact: NESE TUNCER Raif Cakmur Recruiting Izmir, Turkey Contact: RAIF CAKMUR, PROF.DR Collapse << |
NCT01007630 | Parkinson's Disease | Phase 4 | Unknown | January 2014 | United States, California ... more >> The Parkinson's Institute Sunnyvale, California, United States, 94085 Collapse << |
NCT00399477 | Parkinson's Disease | Phase 4 | Completed | - | - |
NCT01497652 | Parkinson's Disease | Phase 4 | Completed | - | United States, District of Col... more >>umbia Georgetown University Hospital Washington, District of Columbia, United States, 20007 Collapse << |
NCT01532141 | Parkinson Disease | Phase 1 | Completed | - | France ... more >> BIOTRIAL Rennes, France, F-35000 Collapse << |
NCT01479530 | Parkinson's Disease | Phase 3 | Completed | - | China ... more >> CN015 Beijing, China, 100034 CN008 Beijing, China, 100050 CN017 Beijing, China, 100050 CN001 Beijing, China, 100730 CN018 Beijing, China, 100730 CN011 Chengdu, China, 610041 CN003 Guangzhou, China, 510120 CN005 Guangzhou, China, 510180 CN004 Hangzhou, China, 310009 CN019 Qingyu Zhou, China, 510260 CN020 Qingyu Zhou, China, 510260 CN012 Shanghai, China, 200025 CN007 Shanghai, China, 200040 CN013 Shanghai, China, 200127 CN006 Suzhou, China, 215004 CN009 Wuhan, China, 430022 CN010 Xi'an, China, 710032 CN014 Zi'an, China, 710061 Collapse << |
NCT01879241 | Amyotrophic Lateral Sclerosis | Phase 2 | Completed | - | Germany ... more >> Department of Neurology, University of Ulm Ulm, Baden-Württemberg, Germany, 89081 Department of Neurology, Technische Universität München Muenchen, Bayern, Germany, D-81675 Department of Neurology, Universty of Regensburg Regensburg, Bayern, Germany, D-93053 Department of Neurology, University of Wuerzburg Wuerzburg, Bayern, Germany, 91054 Department of Neurology, Deutsche Klinik für Diagnostik Wiesbaden, Hessen, Germany, D-65191 Department of Neurology, University of Rostock Rostock, Mecklenburg-Vorpommern, Germany, D-18147 Department of Neurology, University of Goettingen Goettingen, Niedersachsen, Germany, D-37073 Department of Neurology, Medical School Hannover Hannover, Niedersachsen, Germany, 30625 Neurologische Universitätsklinik Bergmannsheil Bochum, Nordrhein-Westfalen, Germany, 44789 Department of Neurology, Universty of Muenster Muenster, Nordrhein-Westfalen, Germany, D-48149 Department of Neurology, Universty of Bonn Bonn, Nordrhrein-Westfalen, Germany, D-53105 Department of Neurology, University of Halle-Wittenberg Halle/Saale, Sachsen-Anhalt, Germany, 06097 Department of Neurology, TU Dresden Dresden, Sachsen, Germany, D-01307 Department of Neurology, University of Jena Jena, Thueringen, Germany, D-07747 Department of Neurology, Humboldt University Berlin, Germany, 13353 Collapse << |
NCT01479530 | - | - | Completed | - | - |
NCT01723228 | Parkinson's Disease | Phase 4 | Completed | - | - |
NCT01556165 | Parkinson's Disease | Phase 3 | Completed | - | China ... more >> CN015 Beijing, China, 100034 CN001 Beijing, China, 100730 CN011 Chengdu, China, 610041 CN003 Guangzhou, China, 510120 CN005 Guangzhou, China, 510180 CN017 Guangzhou, China, 510260 CN004 Hangzhou, China, 310009 CN012 Shanghai, China, 200025 CN007 Shanghai, China, 200040 CN013 Shanghai, China, 200127 CN006 Suzhou, China, 215004 CN009 Wuhan, China, 430022 CN016 Wuhan, China, 430030 CN010 Xi'an, China, 710032 CN014 Xi'an, China, 710061 Collapse << |
NCT01556165 | - | - | Completed | - | - |
NCT00755027 | Parkinson's Disease | Phase 4 | Completed | - | Spain ... more >> Fundacio de Gestio Sanitaria de l'Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 Collapse << |
NCT01232738 | Amyotrophic Lateral Sclerosis ... more >>(ALS) Collapse << | Phase 2 | Completed | - | United States, Arizona ... more >> Phoenix Neurological Institute Phoenix, Arizona, United States, 85018 United States, California California Pacific Medical Center San Francisco, California, United States, 94118 United States, Iowa University of Iowa Iowa City, Iowa, United States, 52242 United States, Kansas University Of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Minnesota University of Minnesota Minneapolis, Minnesota, United States, 55414 United States, Nebraska University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104 United States, Tennessee University of Tennessee Memphis, Tennessee, United States, 38104 United States, Texas The Methodist Hospital System Houston, Texas, United States, 77030 Canada, Quebec McGill University Montreal, Quebec, Canada, H3A 2B4 Collapse << |
NCT01723228 | - | - | Completed | - | - |
NCT01192503 | Restless Legs Syndrome | Phase 2 Phase 3 | Terminated(Slow enrollment) | - | United States, Florida ... more >> Advent Research Pinellas Park, Florida, United States, 33781 United States, Georgia Medical College of Georgia Movements Disorders Program Augusta, Georgia, United States, 30912 United States, Illinois Northwestern University PD and Movement Disorders Center Chicago, Illinois, United States, 60611 United States, New Jersey Atlantic Neuroscience Institute Overlook Hospital Summit, New Jersey, United States, 07902 United States, New York SUNY- Buffalo Jacobs Neurological Institute Buffalo, New York, United States, 14203 United States, Ohio Cleveland Clinic Sleep Disorders Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania University of Pennsylvania Sleep Center Philadelphia, Pennsylvania, United States, 19104 United States, Virginia Charlottesville Medical Research Charlottesville, Virginia, United States, 22911 Collapse << |
NCT01268891 | - | - | Completed | - | - |
NCT02384512 | - | - | Completed | - | - |
NCT01532141 | - | - | Completed | - | - |
NCT01232738 | - | - | Completed | - | - |
NCT01652313 | Parkinson's Disease | Phase 1 | Completed | - | China ... more >> CN001 Beijing, China Collapse << |
NCT01168596 | - | - | Completed | - | - |
NCT01786603 | Amyotrophic Lateral Sclerosis ... more >>(ALS) Collapse << | Phase 2 | Active, not recruiting | August 2017 | United States, Arizona ... more >> Phoenix Neurological Associates Phoenix, Arizona, United States, 85018 United States, California University of California - Irvine Irvine, California, United States, 92868 California Pacific Medical Center San Francisco, California, United States, 94115 United States, Kansas University of Kansas Medical Center Kansas City, Kansas, United States, 66160 United States, Missouri St. Louis University Saint Louis, Missouri, United States, 63104 United States, Nebraska University of Nebraska Omaha, Nebraska, United States, 68198 United States, New York Columbia University New York, New York, United States, 10032 United States, Oregon Oregon Health and Science University Portland, Oregon, United States, 97239 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19107 United States, Texas UT Southwestern Medical Center Dallas, Texas, United States, 75390 Collapse << |
NCT01736891 | Parkinson´s Disease | Phase 3 | Completed | - | China ... more >> CN002 Chengdu, China, 610041 CN005 Chenzhou, China, 423000 CN007 Chongqing, China, 404000 CN003 Guilin, China, 541001 CN004 Lanzhou, China, 730050 CN006 Luzhou, China, 646000 CN008 Nanjing, China, 210029 CN001 Xi'an, China, 710032 Collapse << |
NCT01178047 | Parkinson's Disease | Phase 4 | Terminated(payments stopped by... more >> grant provider) Collapse << | - | Switzerland ... more >> University Hospital, Neurology Zurich, ZH, Switzerland, CH-8091 Neurocentro, Lugano Lugano, Switzerland Collapse << |
NCT01442610 | Sleep Disturbances ... more >> Parkinsons's Disease Collapse << | Phase 4 | Completed | - | Germany ... more >> Dresden University of Technology, Dept. of Neurology Dresden, Germany, 01307 Collapse << |
NCT00203177 | Parkinson's Disease | Phase 3 | Completed | - | United States, California ... more >> Margolin Brain Institute Fresno, California, United States, 93720 United States, Georgia Emory University Atlanta, Georgia, United States, 30329 United States, Illinois Rush - Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, Nebraska Creighton University Omaha, Nebraska, United States, 68131 United States, New York Long Island Jewish Medical Center New Hyde Park, New York, United States, 11040 University of Rochester Rochester, New York, United States, 14642 United States, Pennsylvania Pennsylvania Hospital Philadelphia, Pennsylvania, United States, 19107 Canada, Quebec CHUM-Hotel-Dieu Montreal, Quebec, Canada, H2w1T8 Collapse << |
NCT00977665 | Multiple System Atrophy | Phase 2 | Completed | - | - |
NCT00936676 | - | - | Completed | - | - |
NCT01032486 | - | - | Completed | - | - |
NCT00977665 | - | - | Completed | - | - |
NCT03727139 | - | - | Recruiting | October 31, 2021 | Japan ... more >> Takeda Selected Site Recruiting Tokyo, Japan Collapse << |
NCT01168596 | Parkinson's Disease | Phase 4 | Completed | - | United States, Colorado ... more >> University of Colorado Anschutz outpatient Pavilion Aurora, Colorado, United States, 80045 United States, Florida Shands and University of Florida Medical Plaza Gainesville, Florida, United States, 32610 United States, Ohio Cleveland Clinic Center for Neurological Restoration Cleveland, Ohio, United States, 44195 Collapse << |
NCT00203164 | Parkinson's Disease | Phase 3 | Completed | - | United States, California ... more >> Margolin Brain Institute Fresno, California, United States, 93720 United States, Illinois Rush - Presbyterian St. Luke's Medical Center Chicago, Illinois, United States, 60612 United States, Nebraska Creighton University Omaha, Nebraska, United States, 68131 United States, New York Long Island Jewish Medical Center New Hyde Park, New York, United States, 11040 University of Rochester Rochester, New York, United States, 14642 United States, Pennsylvania Pennsylvania Hospital Philadelphia, Pennsylvania, United States, 19107 Collapse << |
NCT01879748 | Parkinson's Disease | Phase 1 | Completed | - | United States, California ... more >> Teva Investigational Site 10738 Glendale, California, United States Collapse << |
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