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CAS No.: 61379-65-5
Synonyms: DL 473;Cyclopentylrifampicin;MDL473
Rifapentine is an antibiotic compound, which inhibits DNA-dependent RNA polymerase activity, used to treat tuberculosis.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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NCT02099240 | Osteomyelitis | Early Phase 1 | Recruiting | September 2019 | United States, Kentucky ... more >> University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Julio A Ramirez, MD 502-852-1148 jarami01@louisville.edu Contact: David Seligson, MD 502-852-0923 d0seli01@louisville.edu Sub-Investigator: Forest Arnold, DO Sub-Investigator: Timothy Wiemkwn, PhD Sub-Investigator: Robert Kelley, PhD Sub-Investigator: James Summersgill, PhD Sub-Investigator: Ruth Carrico, PhD Sub-Investigator: Julie Harting, PharmD Sub-Investigator: Paula Peyrani, MD Principal Investigator: David Seligson, MD Sub-Investigator: Craig Roberts, MD Principal Investigator: Julio Ramirez, MD Collapse << |
NCT03474198 | Tuberculosis, Pulmonary | Phase 2 Phase 3 | Recruiting | March 12, 2022 | Philippines ... more >> De La Salle Health Sciences Institute Not yet recruiting Manila, Philippines Lung Center Philippines Recruiting Manila, Philippines Philippines Tuberculosis Society Incorporated (PTSI) Not yet recruiting Manila, Philippines Tropical Disease Foundation Not yet recruiting Manila, Philippines Singapore National University Hospital Not yet recruiting Singapore, Singapore Thailand King Chulalongkorn Memorial Hospital Not yet recruiting Bangkok, Thailand Collapse << |
NCT02689089 | Tuberculosis | Phase 4 | Recruiting | September 2019 | Canada, Ontario ... more >> The Ottawa Hospital - General Campus Recruiting Ottawa, Ontario, Canada, K1H 8L6 Contact: Gonzalo Alvarez, MD 613-737-8899 galvarez@ottawahospital.on.ca Principal Investigator: Gonzalo Alvarez, MD, FRCPC Collapse << |
实验方案
技术信息
CAS号 | 61379-65-5 | 储存条件 |
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分子式 | C47H64N4O12 | 运输 | 蓝冰 | |||||||
分子量 | 877.03 | 别名 | DL 473;Cyclopentylrifampicin;MDL473;R-773;利福喷丁 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02099240 | Osteomyelitis | Early Phase 1 | Recruiting | September 2019 | United States, Kentucky ... more >> University of Louisville Recruiting Louisville, Kentucky, United States, 40202 Contact: Julio A Ramirez, MD 502-852-1148 jarami01@louisville.edu Contact: David Seligson, MD 502-852-0923 d0seli01@louisville.edu Sub-Investigator: Forest Arnold, DO Sub-Investigator: Timothy Wiemkwn, PhD Sub-Investigator: Robert Kelley, PhD Sub-Investigator: James Summersgill, PhD Sub-Investigator: Ruth Carrico, PhD Sub-Investigator: Julie Harting, PharmD Sub-Investigator: Paula Peyrani, MD Principal Investigator: David Seligson, MD Sub-Investigator: Craig Roberts, MD Principal Investigator: Julio Ramirez, MD Collapse << |
NCT03474198 | Tuberculosis, Pulmonary | Phase 2 Phase 3 | Recruiting | March 12, 2022 | Philippines ... more >> De La Salle Health Sciences Institute Not yet recruiting Manila, Philippines Lung Center Philippines Recruiting Manila, Philippines Philippines Tuberculosis Society Incorporated (PTSI) Not yet recruiting Manila, Philippines Tropical Disease Foundation Not yet recruiting Manila, Philippines Singapore National University Hospital Not yet recruiting Singapore, Singapore Thailand King Chulalongkorn Memorial Hospital Not yet recruiting Bangkok, Thailand Collapse << |
NCT02689089 | Tuberculosis | Phase 4 | Recruiting | September 2019 | Canada, Ontario ... more >> The Ottawa Hospital - General Campus Recruiting Ottawa, Ontario, Canada, K1H 8L6 Contact: Gonzalo Alvarez, MD 613-737-8899 galvarez@ottawahospital.on.ca Principal Investigator: Gonzalo Alvarez, MD, FRCPC Collapse << |
NCT00057122 | HIV Infections ... more >> Tuberculosis Collapse << | Phase 3 | Completed | - | South Africa ... more >> Chris Hani Baragwanath Hospital Soweto, South Africa Collapse << |
NCT03089983 | Opioid Dependence ... more >> Addiction HIV/AIDS Tuberculosis Hepatitis Collapse << | Phase 4 | Recruiting | April 2021 | Malaysia ... more >> Kajang Prison Recruiting Kajang, Selangor, Malaysia Contact: Adeeba Kamarulzaman, MBBS Principal Investigator: Adeeba Kamarulzaman, MBBS Collapse << |
NCT02771249 | Healthy Volunteers | Phase 1 | Recruiting | December 31, 2019 | United States, Maryland ... more >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov Collapse << |
NCT00002192 | Mycobacterium Avium-Intracellu... more >>lare Infection HIV Infections Collapse << | Phase 2 | Completed | - | United States, Virginia ... more >> Hampton Roads Med Specialists Hampton, Virginia, United States, 23666 Collapse << |
NCT01582711 | Latent Tuberculosis Infection | Phase 3 | Completed | - | United States, California ... more >> University of California, San Francisco San Francisco, California, United States, 94110 United States, Colorado Denver Public Health Department Denver, Colorado, United States, 80204 United States, District of Columbia Washington DC Veterans Affairs Medical Center Washington, District of Columbia, United States, 20422 United States, New York Columbia University College of Physicians and Surgeons and New York City Department of Health New York, New York, United States, 10032 United States, North Carolina Duke University Durham, North Carolina, United States, 27713 United States, Tennessee Vanderbilt University Medical Center and Nashville Metro Public Health Department Nashville, Tennessee, United States, 37232-0146 United States, Texas University of North Texas Health Science Center at Fort Worth Fort Worth, Texas, United States, 76104-4802 Audie L. Murphy VA Hospital San Antonio, Texas, United States, 78229-4404 South Texas - Department of State Health Services San Antonio, Texas, United States, 78229-4404 China TB and Chest service of Hong Kong Hong Kong, China South Africa Wits Health Consortium Soweto, South Africa Spain Agencia de Salut Publica - Barcelona, Spain and UNTHSC Barcelona, Spain, 08023 Collapse << |
NCT00023335 | Pulmonary Tuberculosis | Phase 3 | Completed | - | - |
NCT02735590 | Tuberculosis | Phase 2 Phase 3 | Enrolling by invitation | May 30, 2019 | South Africa ... more >> Centre for the Aids Programme of Research in South Africa (CAPRISA) Durban, KwaZulu-Natal, South Africa, 4013 Aurum Institute Klerksdorp, North West Province, South Africa, 2571 Aurum Institute Rustenburg, North West, South Africa, 0300 Stellenbosch Immunology Research Group Cape Town, Western Cape, South Africa, 7505 South African Tuberculosis Vaccine Initiative (SATVI) Worcester, Western Cape, South Africa, 6850 Collapse << |
NCT01404312 | - | - | Completed | - | - |
NCT03435146 | Respiratory Tract Infections ... more >> HIV Infections Collapse << | Phase 1 Phase 2 | Recruiting | November 3, 2018 | South Africa ... more >> The Aurum Institute: Tembisa Clinical Research Centre Recruiting Tembisa, Gauteng, South Africa, 1736 Contact: Modulakgotla Sebe, BCh, MB 27-87-1351645 msebe@auruminstitute.org Collapse << |
NCT02651259 | Tuberculosis | Phase 1 Phase 2 | Active, not recruiting | March 31, 2019 | Haiti ... more >> Les Centres GHESKIO Clinical Research Site (GHESKIO-INLR) CRS Port-au-Prince, Haiti, HT-6110 Kenya Kenya Medical Research Institute / Walter Reed Project Clinical Research Center, Kericho CRS Kericho, Kenya, 20200 Malawi Malawi CRS Lilongwe, Central Malawi, Malawi Thailand Siriraj Hospital ,Mahidol University NICHD CRS Bangkok, Bangkoknoi, Thailand, 10700 Zimbabwe Harare Family Care CRS Harare, Zimbabwe Collapse << |
NCT03266991 | Compliance, Patient | Phase 4 | Recruiting | January 2020 | Denmark ... more >> Dept of Pulmonary Medicine Recruiting Aarhus, Denmark, 8000 Contact: Nina B Staerke, MD ninase@rm.dk Dept of Pulmonary Medicine Recruiting Esbjerg, Denmark, 6700 Contact: Torben Jensen, MD Collapse << |
NCT02208427 | Latent Tuberculosis Infection | Phase 3 | Unknown | December 2016 | Taiwan ... more >> National Taiwan University Hospital Taipei, Taiwan, 100 Collapse << |
NCT01404312 | Tuberculosis ... more >>HIV Infections Collapse << | Phase 3 | Completed | - | - |
NCT00023426 | Tuberculosis | Phase 2 | Completed | - | - |
NCT03510468 | Healthy Volunteers | Phase 1 | Recruiting | August 30, 2021 | United States, Maryland ... more >> National Institutes of Health Clinical Center Recruiting Bethesda, Maryland, United States, 20892 Contact: For more information at the NIH Clinical Center contact Office of Patient Recruitment (OPR) 800-411-1222 ext TTY8664111010 prpl@cc.nih.gov Collapse << |
NCT01162486 | Tuberculosis ... more >>Tuberculosis, Pulmonary Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> Johns Hopkins University Baltimore, Maryland, United States, 21287 Collapse << |
NCT02641106 | Tuberculosis ... more >>Latent Tuberculosis Infection Collapse << | Not Applicable | Recruiting | December 2019 | United States, California ... more >> San Diego County Health and Human Services Agency Recruiting San Diego, California, United States, 92110 Contact: Wilma J Wooten, M.D., M.P.H 619-515-6597 Wilma.Wooten@sdcounty.ca.gov Contact: Antonette Antonio, NP, RN 619-692-5718 Antonette.Antonio@sdcounty.ca.gov Collapse << |
NCT01574638 | Tuberculosis | Phase 1 | Completed | - | United States, California ... more >> UCSD Antiviral Research Center CRS San Diego, California, United States, 92103 United States, Maryland Johns Hopkins University CRS Baltimore, Maryland, United States, 21205 United States, North Carolina Chapel Hill CRS Chapel Hill, North Carolina, United States, 27599 United States, Tennessee Vanderbilt Therapeutics (VT) CRS Nashville, Tennessee, United States, 37204 Collapse << |
NCT01690403 | Tuberculosis | Phase 1 | Completed | - | United States, New York ... more >> Investigational Site Number 840001 Buffalo, New York, United States, 14202 Collapse << |
NCT00164450 | Tuberculosis | Not Applicable | Completed | - | - |
NCT00023452 | - | - | Completed | - | - |
NCT00023452 | Tuberculosis | Phase 3 | Completed | - | - |
NCT02563327 | Tuberculosis | Phase 3 | Recruiting | March 2020 | Uganda ... more >> Mulago Hospital Recruiting Kampala, Uganda Contact: Principal Investigator jlj@case.edu Collapse << |
NCT00023387 | Tuberculosis | Not Applicable | Completed | - | - |
NCT00460759 | Mycobacterium Tuberculosis | Phase 1 | Terminated | - | United States, Maryland ... more >> Johns Hopkins University Baltimore, Maryland, United States, 21287 Collapse << |
NCT02430259 | Silicosis Tub... more >>erculosis Collapse << | Phase 3 | Unknown | December 2018 | China, Zhejiang ... more >> Wenling No.1 People's Hospital, Zhejiang Recruiting Taizhou, Zhejiang, China, 317500 Contact: Xuefeng Liu, MD +86576-86206803 lhpxf@163.com Sub-Investigator: Xitian Huang, MD Collapse << |
NCT02980016 | Tuberculosis ... more >>HIV Collapse << | Phase 3 | Active, not recruiting | September 2019 | South Africa ... more >> The Aurum Institute NPC Johannesburg, Gauteng, South Africa, 2193 Collapse << |
NCT00728507 | Tuberculosis | Phase 2 | Terminated(Funding withdrawn) | - | Brazil ... more >> Centro de Referência Professor Hélio Fraga - ENSP - FIOCRUZ Curicica, Rio de Janeiro, Brazil, 22.780-192 Posto de Saude Albert Sabin Rio de Janeiro, RJ, Brazil, 20211-110 Hospital Universitario Clementio Fraga Filho Rio de Janeiro, Brazil Collapse << |
NCT02410772 | Tuberculosis | Phase 3 | Recruiting | December 2019 | - |
NCT00814671 | Tuberculosis | Phase 2 | Completed | - | South Africa ... more >> Universiy of Cape Town Lung Institute Cape Town, Western Cape, South Africa, 7937 Collapse << |
NCT02216331 | Tuberculosis | Phase 1 | Completed | - | United States, Nebraska ... more >> Celerion (MDS Pharma Services) Lincoln, Nebraska, United States, 68502 Collapse << |
NCT03730181 | Latent Tuberculosis | Phase 1 Phase 2 | Not yet recruiting | February 2022 | - |
NCT00809718 | Healthy | Phase 1 | Completed | - | United States, Texas ... more >> Audie L Murphy Veterans Administration Hospital San Antonio, Texas, United States, 78229 University of Texas Health Science Center San Antonio, Texas, United States, 78229 Collapse << |
NCT01043575 | Smear Positive, Pan-sensitive,... more >> Pulmonary Tuberculosis Collapse << | Phase 2 | Completed | - | United States, Colorado ... more >> Denver Public Health Denver, Colorado, United States United States, Texas University of North Texas Denton, Texas, United States TBTC site 40 / South Texas Harlingen, Texas, United States Audie L. Murphy VA Medical Center San Antonio, Texas, United States South Africa University of KwaZulu Natal Durban, South Africa Uganda Uganda / Case Western Reserve Research Collaboration Kampala, Uganda Collapse << |
NCT03474029 | Latent Tuberculosis | Phase 2 Phase 3 | Not yet recruiting | December 2020 | - |
NCT00728507 | - | - | Terminated(Funding withdrawn) | - | - |
NCT00694629 | Pulmonary Tuberculosis | Phase 2 | Completed | - | - |
NCT00814671 | - | - | Completed | - | - |
靶点 | Description | IC50 |
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