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CAS No.: 920113-03-7
Synonyms: P276-00;Riviciclib Hydrocloride;Riviciclib
P276-00 is a CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01903018 | Radiation Induced Mucositis in... more >> Head and Neck Cancer Collapse << | Phase 2 | Completed | - | India ... more >> Bharat Cancer Hospital & Research Institute Surat, Gujarat, India, 395010 Sri Venkateshwara Hospitals Bangalore, Karnataka, India, 560068 Mazumdar Shaw Cancer Center Bangalore, Karnataka, India, 560099 Tata Memorial Hospital Mumbai, Maharashtra, India, 400012 Curie Manavta Cancer Centre Nashik, Maharashtra, India, 422004 Ruby Hall Clinic Pune, Maharashtra, India, 411001 Meenakshi Mission Hosp. & Res. Centre Madurai, Tamil Nadu, India, 625107 Collapse << |
NCT00547404 | Multiple Myeloma | Phase 1 | Withdrawn(Not to expose the pa... more >>tients to subtherapeutic dose) Collapse << | July 2010 | - |
NCT00407498 | Neoplasm | Phase 1 | Completed | - | Canada, Ontario ... more >> Juravinsky Cancer Centre Hamilton, Ontario, Canada, L8V5C2 Kingston General Hospital Kingston, Ontario, Canada, K7L 2V7 India Nizam's Institute of Medicai Sciences Hyderabaad, Andhrapradesh, India, 500082 Collapse << |
实验方案
技术信息
CAS号 | 920113-03-7 | 储存条件 |
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分子式 | C21H21Cl2NO5 | 运输 | 蓝冰 | |
分子量 | 438.30 | 别名 | P276-00;Riviciclib Hydrocloride;Riviciclib;Riviciclib HCl |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01903018 | Radiation Induced Mucositis in... more >> Head and Neck Cancer Collapse << | Phase 2 | Completed | - | India ... more >> Bharat Cancer Hospital & Research Institute Surat, Gujarat, India, 395010 Sri Venkateshwara Hospitals Bangalore, Karnataka, India, 560068 Mazumdar Shaw Cancer Center Bangalore, Karnataka, India, 560099 Tata Memorial Hospital Mumbai, Maharashtra, India, 400012 Curie Manavta Cancer Centre Nashik, Maharashtra, India, 422004 Ruby Hall Clinic Pune, Maharashtra, India, 411001 Meenakshi Mission Hosp. & Res. Centre Madurai, Tamil Nadu, India, 625107 Collapse << |
NCT00547404 | Multiple Myeloma | Phase 1 | Withdrawn(Not to expose the pa... more >>tients to subtherapeutic dose) Collapse << | July 2010 | - |
NCT00407498 | Neoplasm | Phase 1 | Completed | - | Canada, Ontario ... more >> Juravinsky Cancer Centre Hamilton, Ontario, Canada, L8V5C2 Kingston General Hospital Kingston, Ontario, Canada, K7L 2V7 India Nizam's Institute of Medicai Sciences Hyderabaad, Andhrapradesh, India, 500082 Collapse << |
NCT00408018 | Neoplasm | Phase 1 | Terminated(The decision to ter... more >>minate this study after 202 mg/m2 cohort was taken as MTD achieved in other study at 185 mg/m2) Collapse << | - | India ... more >> Nizam's Institute of Medicai Sciences Hyderabaad, Andhra Pradesh, India, 500082 Global Hospital Hyderabad, Andhra Pradesh, India Tata Memorial Hospital Mumbai, Maharashtra, India, 400012 Collapse << |
NCT00824343 | Squamous Cell Carcinoma of Hea... more >>d and Neck Collapse << | Phase 2 | Completed | - | India ... more >> Bharath Hospital & Institute of Oncology, Mysore Mysore, Karnataka, India, 570017 Regional Cancer Centre Trivandrum, Kerala, India, 695011 Kashyap Nursing Home Mumbai, Maharashtra, India, 400014 Jaslok Hospital, Mumbai Mumbai, Maharashtra, India, 400026 Central India Cancer Research Institute, Nagpur, Maharashtra, India, 440010 Deenanath Mangeshkar Hospital & Research Centre Pune, Maharashtra, India, 411004 Bhagwan Mahaveer Cancer Hospital & Research Centre, Dept. Of Medical Oncology, Jaipur Jaipur, Rajasthan, India, 302 017 V. N. Cancer Centre, GKNM Hospital, Coimbatore, Tamilnadu, India, 641037 Dept. Of Surgical Oncology, CSM Medical University, Lucknow Lucknow, UttarPradesh, India, 226003 Collapse << |
NCT00835419 | Melanoma | Phase 2 | Completed | - | Australia, New South Wales ... more >> University of Newcastle, School of Medicine and Public Health Newcastle, New South Wales, Australia, 2300 Australia Mater Adult Hospital Raymond Tce South Brisbane, QLD 4101 Brisbane, Australia Peninsula Oncology Centre Frankston, Australia, 3199 John Fawkner Cancer Trial Centre Victoria, Australia, 3058 India Curie Manavata Cancer Center Nasik, Maharashtra, India, 422 004 Chhatrapati Shahuji Maharaj Medical University Lucknow, Uttar Pradesh, India, 22600 New Zealand Christchurch Oncology Research Unit, Oncology Service, Christchurch Hospital, Riccarton Avenue, Private Bag 4710, Christchurch, Christchurch, New Zealand Collapse << |
NCT01333137 | Breast Cancer | Phase 1 | Terminated | - | United States, California ... more >> Disney Cancer Center Burbank, California, United States 3855 Health Sciences Drive La Jolla, California, United States, 92093 UC Davis Cancer Center Sacramento, California, United States, 95817 United States, Missouri Washington University St. Louis, Missouri, United States Collapse << |
NCT00843050 | - | - | Terminated(The study was termi... more >>nated based on interim results and all subjects were off study at that time. No major safety or tolerability concerns) Collapse << | - | - |
NCT00882063 | Relapsed and/or Refractory Mul... more >>tiple Myeloma Collapse << | Phase 1 Phase 2 | Completed | - | India ... more >> Jaslok Hospital & Research Centre Mumbai, Maharashtra, India, 400 026 Shatabdi Superspeciality Hospital Nasik, Maharashtra, India, 422002 Netaji Subhash Chandra Bose Cancer Research Institute Kolkata, West Bengal, India, 700016 Rajiv Gandhi Cancer Institute And Research Centre Delhi, India, 110085 Institute Rotary Cancer Hospital,All India Institute Of Medical Sciences(AIIMS) New Delhi, India, 110029 Collapse << |
NCT00899054 | Squamous Cell Carcinoma of Hea... more >>d and Neck Collapse << | Phase 1 Phase 2 | Completed | - | India ... more >> Government Medical College Aurangabad, Maharashtra, India, 431001 Curie Manavata Cancer Center Nashik, Maharashtra, India, 422 004 Bhagwan Mahawir Cancer Hospital & Research Centre Jaipur, Rajasthan, India, 302017 V. N. Cancer Centre, GKNM Hospital Coimbatore, Tamil Nadu, India, 641037 Meenakshi Mission Hospital & Research Centre Madurai, Tamil Nadu, India, 625107 Christian Medical College Vellore, Tamil Nadu, India, 632 004 Collapse << |
NCT00843050 | Mantle Cell Lymphoma | Phase 2 | Terminated(The study was termi... more >>nated based on interim results and all subjects were off study at that time. No major safety or tolerability concerns) Collapse << | August 2012 | United States, Arizona ... more >> Division of Hematology/Oncology, Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona Phoenix, Arizona, United States, 85054 Division of Hematology/Oncology, Department of Internal Medicine, Mayo Clinic, Arizona Scottsdale, Arizona, United States, 85259 United States, Minnesota College of Medicine, Mayo Clinic Rochester, Minnesota, United States, 55905 United States, New Jersey Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 United States, Ohio Gabrail Cancer Center Research Canton, Ohio, United States, 44718 Gabrail Cancer Center Research Dover, Ohio, United States, 44622 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232-5505 United States, Texas Cancer Care Centers of South Texas New Braunfels, Texas, United States, 78130 Cancer Care Centers of South Texas San Antonio, Texas, United States, 78229 United States, Utah Huntsman Cancer Institute, 2000 Circle of Hope, Room 2145 Salt Lake City, Utah, United States, 84112 United States, Washington Seattle Cancer Care Alliance Seattle, Washington, United States, 98109 Department of Medicine, University of Washington Seattle, Washington, United States, 98195 United States, Wisconsin Dept of Hematology/Oncology, University of Wisconsin- Madison Madison, Wisconsin, United States, 53792-5156 India Institute Rotary Cancer Hospital, All India Institute of Medical Sciences New Delhi, Delhi, India, 10029 St. Johns Medical College & Hospital Bangalore, Karnataka, India, 34 Malabar Institute of Medical Sciences Calicut, Kerala, India, 16 Jaslok Hospital and Research Centre Mumbai, Maharashtra, India, 400 026 Tata Memorial Hospital Mumbai, Maharashtra, India, 400012 Cancer Care Clinic and Hospital Nagpur, Maharashtra, India, 440012 Meenakshi mission hospital and research centre Madurai, Tamil nadu, India, 625107 Collapse << |
NCT00898287 | Pancreatic Cancer | Phase 1 Phase 2 | Completed | - | India ... more >> Central India Cancer Research Institute Nagpur, Ajayonco@hotmail.com, India, 440 010 Global Hospital Hyderabaad, Andhra Pradesh, India, 500004 Curie Manavata Cancer Centre Nashik, Maharashtra, India, 422 004 Deenanath Mangeshkar Hospital & Research Centre Pune, Maharashtra, India, 411004 Sri RamaChandra Medical Centre Chennai, Tamil Nadu, India, 600 116 Lifeline Mutispecilaity Hospital Chennai, Tamil Nadu, India, 600096 Meenakshi Mission Hospital & Reasearch Centre Madurai, Tamil Nadu, India, 625107 Collapse << |
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