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CAS No.: 1050670-85-3

Ro-51 Catalog No. CSN19854

Ro 51 is a potent, dual P2X3 and P2X2/3 antagonist (IC50 values are 2 and 5 nM for rP2X3 and hP2X2/3 respectively).

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描述Ro 51 is a potent, dual P2X3 and P2X2/3 antagonist (IC50 values are 2 and 5 nM for rP2X3 and hP2X2/3 respectively).
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT03155620	Advanced Malignant Solid Neopl... more >>asm Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma Ann Arbor Stage IV Childhood Non-Hodgkin Lymphoma Childhood Langerhans Cell Histiocytosis Histiocytic Sarcoma Juvenile Xanthogranuloma Malignant Glioma Recurrent Central Nervous System Neoplasm Recurrent Childhood Ependymoma Recurrent Childhood Malignant Germ Cell Tumor Recurrent Childhood Medulloblastoma Recurrent Childhood Non-Hodgkin Lymphoma Recurrent Childhood Rhabdomyosarcoma Recurrent Childhood Soft Tissue Sarcoma Recurrent Ewing Sarcoma Recurrent Glioma Recurrent Hepatoblastoma Recurrent Langerhans Cell Histiocytosis Recurrent Malignant Solid Neoplasm Recurrent Neuroblastoma Recurrent Osteosarcoma Recurrent Peripheral Primitive Neuroectodermal Tumor Recurrent Rhabdoid Tumor Refractory Central Nervous System Neoplasm Refractory Childhood Malignant Germ Cell Tumor Refractory Ewing Sarcoma Refractory Glioma Refractory Hepatoblastoma Refractory Langerhans Cell Histiocytosis Refractory Malignant Solid Neoplasm Refractory Medulloblastoma Refractory Neuroblastoma Refractory Non-Hodgkin Lymphoma Refractory Osteosarcoma Refractory Peripheral Primitive Neuroectodermal Tumor Refractory Rhabdoid Tumor Refractory Rhabdomyosarcoma Rhabdoid Tumor Stage III Osteosarcoma AJCC v7 Stage III Soft Tissue Sarcoma AJCC v7 Stage IV Osteosarcoma AJCC v7 Stage IV Soft Tissue Sarcoma AJCC v7 Stage IVA Osteosarcoma AJCC v7 Stage IVB Osteosarcoma AJCC v7 Wilms Tumor Collapse <<	Phase 2	Recruiting	September 30, 2027	-
NCT03066804	Heart Failure With Preserved E... more >>jection Fraction Collapse <<	Phase 3	Recruiting	December 4, 2019	-
NCT01288911	Prostatic Neoplasms	Phase 2	Completed	-	-

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实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.1084 mL
- 10.5420 mL
- 21.0840 mL
- 5 mM
- 0.4217 mL
- 2.1084 mL
- 4.2168 mL
- 10 mM
- 0.2108 mL
- 1.0542 mL
- 2.1084 mL

技术信息

CAS号	1050670-85-3		储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C17H23IN4O4		运输	蓝冰
分子量	474.29		别名

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT03155620	Advanced Malignant Solid Neopl... more >>asm Ann Arbor Stage III Childhood Non-Hodgkin Lymphoma Ann Arbor Stage IV Childhood Non-Hodgkin Lymphoma Childhood Langerhans Cell Histiocytosis Histiocytic Sarcoma Juvenile Xanthogranuloma Malignant Glioma Recurrent Central Nervous System Neoplasm Recurrent Childhood Ependymoma Recurrent Childhood Malignant Germ Cell Tumor Recurrent Childhood Medulloblastoma Recurrent Childhood Non-Hodgkin Lymphoma Recurrent Childhood Rhabdomyosarcoma Recurrent Childhood Soft Tissue Sarcoma Recurrent Ewing Sarcoma Recurrent Glioma Recurrent Hepatoblastoma Recurrent Langerhans Cell Histiocytosis Recurrent Malignant Solid Neoplasm Recurrent Neuroblastoma Recurrent Osteosarcoma Recurrent Peripheral Primitive Neuroectodermal Tumor Recurrent Rhabdoid Tumor Refractory Central Nervous System Neoplasm Refractory Childhood Malignant Germ Cell Tumor Refractory Ewing Sarcoma Refractory Glioma Refractory Hepatoblastoma Refractory Langerhans Cell Histiocytosis Refractory Malignant Solid Neoplasm Refractory Medulloblastoma Refractory Neuroblastoma Refractory Non-Hodgkin Lymphoma Refractory Osteosarcoma Refractory Peripheral Primitive Neuroectodermal Tumor Refractory Rhabdoid Tumor Refractory Rhabdomyosarcoma Rhabdoid Tumor Stage III Osteosarcoma AJCC v7 Stage III Soft Tissue Sarcoma AJCC v7 Stage IV Osteosarcoma AJCC v7 Stage IV Soft Tissue Sarcoma AJCC v7 Stage IVA Osteosarcoma AJCC v7 Stage IVB Osteosarcoma AJCC v7 Wilms Tumor Collapse <<	Phase 2	Recruiting	September 30, 2027	-
NCT03066804	Heart Failure With Preserved E... more >>jection Fraction Collapse <<	Phase 3	Recruiting	December 4, 2019	-
NCT01288911	Prostatic Neoplasms	Phase 2	Completed	-	-
NCT02844816	Recurrent Bladder Urothelial C... more >>arcinoma Stage 0a Bladder Urothelial Carcinoma AJCC v6 and v7 Stage 0is Bladder Urothelial Carcinoma AJCC v6 and v7 Stage I Bladder Urothelial Carcinoma AJCC v6 and v7 Collapse <<	Phase 2	Recruiting	February 28, 2020	-
NCT02394535	Pancreatic Adenocarcinoma ... more >> Stage III Pancreatic Cancer AJCC v6 and v7 Collapse <<	Phase 1	Recruiting	November 30, 2019	United States, Texas ... more >> M D Anderson Cancer Center Recruiting Houston, Texas, United States, 77030 Contact: Sunil Krishnan 713-563-2300 skrishnan@mdanderson.org Principal Investigator: Sunil Krishnan MD Anderson Regional Care Center-Katy Not yet recruiting Houston, Texas, United States, 77094 Contact: Sunil Krishnan 713-563-2300 Principal Investigator: Sunil Krishnan MD Anderson Cancer Center - League City Not yet recruiting League City, Texas, United States, 77573 Contact: Sunil Krishnan 713-563-2300 Principal Investigator: Sunil Krishnan MD Anderson Regional Care Center-Sugar Land Not yet recruiting Sugar Land, Texas, United States, 77478 Contact: Sunil Krishnan 713-563-2300 Principal Investigator: Sunil Krishnan MD Anderson Regional Care Center-The Woodlands Not yet recruiting The Woodlands, Texas, United States, 77384 Contact: Sunil Krishnan 713-563-2300 Principal Investigator: Sunil Krishnan Collapse <<
NCT00858338	Gastric Cancer ... more >> Stomach Cancer Collapse <<	Phase 2	Completed	-	United States, New York ... more >> Bellevue Hospital New York, New York, United States, 10016 NYU Cancer Center New York, New York, United States, 10016 NYU Tisch Hospital New York, New York, United States, 10016 Collapse <<
NCT00019682	-	-	Completed	-	-
NCT00019682	Recurrent Melanoma ... more >> Stage IIIA Skin Melanoma Stage IIIB Skin Melanoma Stage IIIC Skin Melanoma Stage IV Skin Melanoma Collapse <<	Phase 3	Completed	-	United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, Arizona Mayo Clinic in Arizona Scottsdale, Arizona, United States, 85259 United States, California Kaiser Permanente Medical Center Riverside, California, United States, 92505 United States, Colorado University of Colorado Cancer Center - Anschutz Cancer Pavilion Aurora, Colorado, United States, 80045 United States, Florida Lakeland Regional Cancer Center Lakeland, Florida, United States, 33805 United States, Georgia Emory University/Winship Cancer Institute Atlanta, Georgia, United States, 30322 United States, Illinois Northwestern University Chicago, Illinois, United States, 60611 Rush University Medical Center Chicago, Illinois, United States, 60612 Advocate Lutheran General Hospital. Park Ridge, Illinois, United States, 60068 United States, Indiana IU Health Goshen Center for Cancer Care Goshen, Indiana, United States, 46526 United States, Kentucky The James Graham Brown Cancer Center at University of Louisville Louisville, Kentucky, United States, 40202 United States, Maryland National Institutes of Health Bethesda, Maryland, United States, 20892 United States, North Carolina Carolinas Medical Center Charlotte, North Carolina, United States, 28203 United States, Ohio The Christ Hospital Cincinnati, Ohio, United States, 45219 Ohio State University Comprehensive Cancer Center Columbus, Ohio, United States, 43210 United States, Pennsylvania Saint Luke's University Hospital-Bethlehem Campus Bethlehem, Pennsylvania, United States, 18015 Penn State Milton S Hershey Medical Center Hershey, Pennsylvania, United States, 17033-0850 United States, Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 United States, Wisconsin Aurora Saint Luke's Medical Center Milwaukee, Wisconsin, United States, 53215 Collapse <<
NCT01288911	-	-	Completed	-	-
NCT02513654	Bipolar Disorder	Phase 1	Completed	-	China ... more >> GSK Investigational Site Shanghai, China, 200030 Collapse <<
NCT02308761	Acute Myeloid Leukemia ... more >> Myelodysplastic Syndromes Collapse <<	Phase 1	Completed	-	United States, Massachusetts ... more >> Dana Farber Cancer Institute Boston, Massachusetts, United States, 02215 United States, New York Weill Cornell Medical College New York, New York, United States, 10065 Collapse <<

总药量计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 动物数量只每天给药次给药天

需要的总药量：mg

工作液计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 给药体积μL

您需要配制的工作液浓度为：mg/mL

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