CAS No.: 202825-46-5
Safinamide mesylate Catalog No. CSN12920
Synonyms: FCE 26743 mesylate;EMD 1195686 mesylate;PNU-151774E
Safinamide mesylate is mesylate salt of safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, and exhibits 5918-fold selectivity against MAO-A.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00627640 Idiopathic Parkinson's Disease Phase 3 Completed - - NCT00605683 Idiopathic Parkinson's Disease Phase 3 Completed - - NCT03753763 Multiple System Atrophy Phase 2 Not yet recruiting March 31, 2020 - - 参考文献
- [1] Binda C, Wang J, et al. Structures of human monoamine oxidase B complexes with selective noncovalent inhibitors: safinamide and coumarin analogs. J Med Chem. 2007 Nov 15;50(23):5848-52.
- [2] Caccia C, Maj R, et al. Safinamide: from molecular targets to a new anti-Parkinson drug. Neurology. 2006 Oct 10;67(7 Suppl 2):S18-23.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 202825-46-5 | 储存条件 |
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| 分子式 | C18H23FN2O5S | 运输 | 蓝冰 | |
| 分子量 | 398.45 | 别名 | FCE 26743 mesylate;EMD 1195686 mesylate;PNU-151774E;FCE-28073;Safinamide (mesylate);FCE 26743;NW-1015;Safinamide mesilate;EMD-1195686;Xadago |
