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CAS No.: 1652561-87-9
SAH-SOS1A is a KRAS-targeting stapled peptide with EC50 values of 106, 109, 154, 140, 155 and 175nM for K-Ras, K-Ras (G12D), K-Ras (G12V), K-Ras (G12C), K-Ras (G12S) and K-Ras (Q61H), respectively. It disrupts the SOS1/KRAS protein interaction and directly inhibit nucleotide association to wild-type and mutant KRAS proteins.
实验方案
技术信息
CAS号 | 1652561-87-9 | 储存条件 |
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分子式 | C100H159N27O28 | 运输 | 蓝冰 | |
分子量 | 2187.50 | 别名 |
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