CAS No.: 356559-13-2
SB-505124 HCl Catalog No. CSN13732
Synonyms: TGF-β RI Kinase Inhibitor III;SB-505124 HCl
SB-505124 HCl is a selective inhibitor of TGFβR for ALK4, ALK5 with IC50 of 129 nM and 47 nM, respectively, also inhibits ALK7, but does not inhibit ALK1, 2, 3, or 6.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Sutariya V, Miladore N, et al. Thermoreversible gel for delivery of activin receptor-like kinase 5 inhibitor SB-505124 for glaucoma filtration surgery. Pharm Dev Technol. 2013 Jul-Aug;18(4):957-62.
- [2] DaCosta Byfield S, et al. SB-505124 is a selective inhibitor of transforming growth factor-beta type I receptors ALK4, ALK5, and ALK7. Mol Pharmacol. 2004 Mar;65(3):744-52.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 356559-13-2 | 储存条件 |
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| 分子式 | C20H22ClN3O2 | 运输 | 蓝冰 | |
| 分子量 | 371.86 | 别名 | TGF-β RI Kinase Inhibitor III;SB-505124 HCl |
