CAS No.: 1094067-13-6
SCH-1473759 HCl Catalog No. CSN17462
SCH-1473759 HCl is a sub-nanomolar Aurora A/B inhibitor with IC50 of 4 nM and 13 nM, respectively.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Basso AD, Liu M, et al. SCH 1473759, a novel Aurora inhibitor, demonstrates enhanced anti-tumor activity in combination with taxanes and KSP inhibitors. Cancer Chemother Pharmacol. 2011 Oct;68(4):923-33.
- [2] Yu T, Tagat JR, et al. Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a] -Pyrazine Core. ACS Med Chem Lett. 2010 Jun 7;1(5):214-8.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1094067-13-6 | 储存条件 |
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| 分子式 | C20H27ClN8OS | 运输 | 蓝冰 | |
| 分子量 | 463.00 | 别名 |
