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CAS No.: 960365-65-5

Silvestrol aglycone Catalog No. CSN18642

Silvestrol aglycone, an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM).

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描述Silvestrol aglycone, an aglycone of potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7 and a 5'myc-UTR-LUC inhibtior (IC50= 0.8 nM).
参考文献

[1] Liu T, Nair SJ, et al. Synthetic silvestrol analogues as potent and selective protein synthesis inhibitors. J Med Chem. 2012 Oct 25;55(20):8859-78.
[2] Kim S, Hwang BY, et al. Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7. Anticancer Res. 2007 Jul-Aug;27(4B):2175-83.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.0899 mL
- 10.4495 mL
- 20.8991 mL
- 5 mM
- 0.4180 mL
- 2.0899 mL
- 4.1798 mL
- 10 mM
- 0.2090 mL
- 1.0450 mL
- 2.0899 mL

技术信息

CAS号	960365-65-5	储存条件	粉末液体 -20°C:3-6 月 -80°C:12月
分子式	C27H26O8	运输	蓝冰
分子量	478.49	别名

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