CAS No.: 923604-59-5
Simeprevir/西咪匹韦 Catalog No. CSN16060
Synonyms: TMC435;TMC435350;HSDB-8227
Simeprevir is an inhibitor of HCV NS3/4A protease with Ki of 0.36 nM and EC50 of 7.8 nM against viral replication.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01628692 - - Completed - - NCT01202825 Hepatitis C Phase 1 Completed - Belgium ... more >> Antwerp, Belgium Collapse << NCT03149289 - - Completed - - - 更多
- 参考文献
- [1] Lin TI, Lenz O, et al. In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitor. Antimicrob Agents Chemother. 2009 Apr;53(4):1377-85.
- [2] Raboisson P, de Kock H, et al. Structure-activity relationship study on a novel series of cyclopentane-containing macrocyclic inhibitors of the hepatitis C virus NS3/4A protease leading to the discovery of TMC435350. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4853-8.
- [3] Izquierdo L, Helle F, François C, Castelain S, Duverlie G, Brochot E. Simeprevir for the treatment of hepatitis C virus infection. Pharmgenomics Pers Med. 2014 Aug 14;7:241-9
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 923604-59-5 | 储存条件 |
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| 分子式 | C38H47N5O7S2 | 运输 | 蓝冰 | |||||||
| 分子量 | 749.94 | 别名 | TMC435;TMC435350;HSDB-8227;西咪匹韦 | |||||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT01628692 | - | - | Completed | - | - |
| NCT01202825 | Hepatitis C | Phase 1 | Completed | - | Belgium ... more >> Antwerp, Belgium Collapse << |
| NCT03149289 | - | - | Completed | - | - |
| NCT03226717 | - | - | Not yet recruiting | December 10, 2017 | Egypt ... more >> yasmin AbdElazim Mohamed Turkey Recruiting Assiut, Egypt Collapse << |
| NCT02799355 | - | - | Completed | - | India ... more >> Department of Gastroenterology, D.M.C. and Hospital Ludhiana, Punjab, India, 141001 Collapse << |
| NCT02057003 | - | - | Recruiting | December 2020 | Spain ... more >> Valme University Hospital Recruiting Seville, Spain, 41014 Contact: Karin Neukam, PhD 0034955015799 karin.neukam@gmail.com Contact: Juan A Pineda, MD 0034955015684 japineda@telefonica.net Collapse << |
| NCT02992457 | Hepatitis C | Phase 4 | Completed | - | Egypt ... more >> Sherief Abd-Elsalam Tanta, Egypt Tanta university hospital Tanta, Egypt Collapse << |
| NCT02932293 | Chronic Hepatitis C Infection | Phase 2 | Withdrawn(The collaborating ph... more >>armaceutical company will not wish to continue with the trial due to the internal issues in the company.) Collapse << | December 2017 | Hong Kong ... more >> Humanity and Health Medical Centre Hong Kong, Hong Kong, 00852 Collapse << |
| NCT02531269 | - | - | Completed | - | Switzerland ... more >> Local Institution Basel, Switzerland Collapse << |
| NCT02118597 | - | - | Terminated(Study terminated du... more >>e to the Sponsor's decision.) Collapse << | - | Hungary ... more >> Budapest, Hungary, 1097 Budapest, Hungary, 1125 Békéscsaba, Hungary, 5600 Debrecen, Hungary, 4032 Eger, Hungary, 3300 Kaposvár, Hungary, 7400 Szombathely, Hungary, 8800 Collapse << |
| NCT01724086 | Chronic Hepatitis C | Phase 2 | Completed | - | Belgium ... more >> Antwerpen, Belgium Brugge, Belgium Brussels, Belgium Edegem, Belgium Gent, Belgium Leuven, Belgium Liège, Belgium Germany Berlin, Germany Hamburg, Germany Mainz, Germany Collapse << |
| NCT02455167 | Hepatitis C | Phase 3 | Active, not recruiting | December 2018 | United States, Colorado ... more >> University of Colorado Denver (Leprino Building) Denver, Colorado, United States, 80045 Collapse << |
| NCT02214420 | Hepatitis C | Phase 4 | Completed | - | United States, California ... more >> Scripps Clinic La Jolla, California, United States, 92037 United States, New York Icahn School of Medicine at Mt. Sinai New York, New York, United States, 10029 United States, Utah Clinical Research Centers of America, LLC Murray, Utah, United States, 84123 Collapse << |
| NCT02118597 | - | - | Terminated(Study terminated du... more >>e to the Sponsor's decision.) Collapse << | - | - |
| NCT02214420 | - | - | Completed | - | - |
| NCT02771405 | Hepatitis C, Chronic ... more >> Hepatocellular Carcinoma Collapse << | Phase 3 | Recruiting | September 2019 | Egypt ... more >> Amr Maged Recruiting Cairo, Egypt, 11441 Contact: Amr Maged amrrasheed88@gmail.com Collapse << |
| NCT03155893 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Celerion Tempe, Arizona, United States, 85283 Collapse << |
| NCT03549832 | HCV Coinfection | Not Applicable | Recruiting | January 2019 | Egypt ... more >> Assiut University Hopsital Recruiting Assiut, Egypt, 71515 Contact: Mohamed A Mekky, MD Collapse << |
| NCT02485262 | - | - | Unknown | November 2016 | United States, California ... more >> Arrowhead Regional Medical Center Recruiting Colton, California, United States, 92347 Contact: Tina Mercado 909-883-2999 Contact: Zeid Kayali, MD 909 883-2999 Collapse << |
| NCT00996476 | Hepatitis C, Chronic | Phase 2 | Completed | - | Japan ... more >> Amagasaki, Japan Hiroshima N/A, Japan Kagoshima, Japan Kawasaki, Japan Kitakyushu, Japan Kurume, Japan Kyoto, Japan Matsumoto, Japan Musashino, Japan Nishinomiya, Japan Ohmura, Japan Osaka-Sayama, Japan Osaka, Japan Sakai, Japan Sapporo, Japan Suita, Japan Tokyo, Japan Touon, Japan Yokohama, Japan Collapse << |
| NCT00996476 | - | - | Completed | - | - |
| NCT01466790 | Hepatitis C | Phase 2 | Completed | - | - |
| NCT01852604 | Chronic Hepatitis C Virus | Phase 2 | Completed | - | - |
| NCT00980330 | Hepatitis C | Phase 2 | Completed | - | - |
| NCT00980330 | - | - | Completed | - | - |
| NCT03059303 | Healthy | Phase 1 | Terminated(Decision to discont... more >>inue development of investigational Hep C treatment regimen JNJ-4178 3 direct acting antivirals - AL-335, ODV & SMV.) Collapse << | - | United States, Arizona ... more >> Celerion Tempe, Arizona, United States, 85283 Collapse << |
| NCT01466790 | - | - | Completed | - | - |
| NCT01485991 | Hepatitis C | Phase 3 | Completed | - | - |
| NCT01485991 | - | - | Completed | - | - |
| NCT01269294 | Hepatitis C | Phase 1 | Completed | - | - |
| NCT02168361 | Chronic Hepatitis C | Phase 4 | Completed | - | United States, Georgia ... more >> Center for Hepatitis C Atlanta, Georgia, United States, 30309 Collapse << |
| NCT02018536 | Healthy | Phase 1 | Completed | - | United States, California ... more >> Cypress, California, United States Collapse << |
| NCT02168361 | - | - | Completed | - | - |
| NCT03277755 | Hepatic Impairment | Phase 1 | Withdrawn(Development program ... more >>of JNJ-4178 was discontinued.) Collapse << | December 22, 2017 | - |
| NCT01323257 | Hepatitis C Virus | Phase 1 | Completed | - | Belgium ... more >> Antwerpen, Belgium Collapse << |
| NCT01290679 | - | - | Completed | - | - |
| NCT00561353 | Hepatitis C, Chronic | Phase 2 | Completed | - | Belgium ... more >> Brugge, Belgium Brussels, Belgium Bruxelles, Belgium Edegem, Belgium Gent, Belgium France Clichy, France Lyon, France Marseille, France Paris Cedex 10, France Paris, France Pessac, France Vandoeuvre Les Nancy, France Germany Berlin, Germany Düsseldorf, Germany Freiburg, Germany Hamburg, Germany Hannover, Germany Kiel, Germany Munchen, Germany Netherlands Amsterdam Zuidoost, Netherlands Poland Bialystok, Poland Kielce, Poland Lodz, Poland Warszawa, Poland United Kingdom London, United Kingdom Plymouth, United Kingdom Collapse << |
| NCT01292239 | Hepatitis C, Chronic | Phase 3 | Completed | - | Japan ... more >> Amagasaki, Japan Chiba, Japan Chuo, Japan Hiroshima, Japan Ichikawa, Japan Ikeda, Japan Inashiki, Japan Iruma, Japan Kagoshima, Japan Kanazawa, Japan Kitakyushu, Japan Kumamoto, Japan Kurume, Japan Kyoto, Japan Matsumoto, Japan Musashino, Japan Nagoya, Japan Niigata, Japan Nishinomiya, Japan Ohmura, Japan Osaka-Sayama, Japan Osaka, Japan Sakai, Japan Sapporo, Japan Sendai, Japan Tokyo, Japan Touon, Japan Yokohama, Japan Collapse << |
| NCT01281839 | - | - | Completed | - | - |
| NCT01205139 | Hepatitis C Virus | Phase 1 | Completed | - | - |
| NCT01292239 | - | - | Completed | - | - |
| NCT01241773 | Hepatitis C Virus | Phase 1 | Completed | - | Germany ... more >> Berlin, Germany Collapse << |
| NCT02064842 | Healthy | Phase 1 | Completed | - | United Kingdom ... more >> Harrow, United Kingdom Collapse << |
| NCT00561353 | - | - | Completed | - | - |
| NCT01281839 | Hepatitis C | Phase 3 | Completed | - | - |
| NCT00752544 | HCV | Phase 1 | Completed | - | - |
| NCT01289782 | - | - | Completed | - | - |
| NCT01290679 | Hepatitis C | Phase 3 | Completed | - | - |
| NCT01846832 | Hepatitis C, Chronic ... more >> Infection Collapse << | Phase 3 | Completed | - | Austria ... more >> Linz, Austria Wien, Austria Belgium Brussels, Belgium Brussel, Belgium Edegem, Belgium France Clichy, France Limoges Cedex, France Orleans, France St Laurent Du Var, France Germany Berlin, Germany Düsseldorf, Germany Frankfurt, Germany Hamburg, Germany Würzburg, Germany Saudi Arabia Riyadh, Saudi Arabia Spain Barcelona, Spain Madrid, Spain Valencia, Spain Valme, Spain United Kingdom Glasgow, United Kingdom London, United Kingdom Collapse << |
| NCT01290731 | Hepatitis C, Chronic | Phase 3 | Completed | - | Japan ... more >> Hiroshima, Japan Ichikawa, Japan Kagoshima, Japan Matsumoto, Japan Musashino, Japan Ohmura, Japan Osaka, Japan Sapporo, Japan Suita, Japan Touon, Japan Collapse << |
| NCT01290731 | - | - | Completed | - | - |
| NCT01288209 | Hepatitis C, Chronic | Phase 3 | Completed | - | Japan ... more >> Amagasaki, Japan Ichikawa, Japan Kagoshima, Japan Kanazawa, Japan Kawasaki, Japan Kitakyushu, Japan Kumamoto, Japan Kurume, Japan Kyoto, Japan Matsumoto, Japan Musashino, Japan Nishinomiya, Japan Osaka-Sayama, Japan Osaka, Japan Sakai, Japan Sapporo, Japan Suita, Japan Tokyo, Japan Yokohama, Japan Collapse << |
| NCT01349465 | Hepatitis C | Phase 3 | Completed | - | - |
| NCT01289782 | Hepatitis C | Phase 3 | Completed | - | - |
| NCT01349465 | - | - | Completed | - | - |
| NCT01366638 | Hepatitis C, Chronic | Phase 3 | Completed | - | Japan ... more >> Amagasaki, Japan Ikeda, Japan Kawasaki, Japan Kumamoto, Japan Niigata, Japan Ohmura, Japan Osaka, Japan Sakai, Japan Sapporo, Japan Suita, Japan Tokyo, Japan Collapse << |
| NCT01366638 | - | - | Completed | - | - |
| NCT01479868 | Hepatitis C Virus Genotype-1 | Phase 3 | Completed | - | - |
| NCT01288209 | - | - | Completed | - | - |
| NCT00741169 | Hepatitis C H... more >>CV Tuberculosis Rifampin Pharmacokinetics Collapse << | Phase 1 | Completed | - | - |
| NCT00938899 | Hepatitis C | Phase 1 | Completed | - | - |
| NCT01124799 | Hepatitis C Virus | Phase 1 | Completed | - | - |
| NCT02885454 | Healthy | Phase 1 | Completed | - | United States, Kansas ... more >> Overland Park, Kansas, United States Collapse << |
| NCT01725529 | - | - | Completed | - | - |
| NCT01486004 | Hepatitis C Virus | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
| NCT00882908 | Hepatitis C | Phase 2 | Completed | - | - |
| NCT01134718 | Hepatitis C Virus | Phase 1 | Completed | - | - |
| NCT01725529 | Hepatitis C, Chronic | Phase 3 | Completed | - | China ... more >> Beijing, China Changchun, China Changsha, China Chengdu, China Chongqing, China Guangzhou, China Hangzhou, China Harbin, China Jinan, China Lanzhou, China Nanjing, China Shanghai, China Shenyang, China Tianjin, China Wuhan, China Zhengzhou, China Korea, Republic of Busan, Korea, Republic of Chuncheon, Gangwon-Do, Korea, Republic of Gyeongsangnam-Do, Korea, Republic of Incheon, Korea, Republic of Seoul, Korea, Republic of Collapse << |
| NCT01479868 | - | - | Completed | - | - |
| NCT01308606 | Hepatitis C | Phase 1 | Completed | - | - |
| NCT00866853 | Hepatitis C V... more >>iruses Collapse << | Phase 1 | Completed | - | - |
| NCT00882908 | - | - | Completed | - | - |
| NCT03099135 | Hepatitis C | Phase 3 | Terminated(Recruitment prematu... more >>rely stopped based on decision to stop HPC program (not due to safety or efficacy results) + On 31 Jan 2018 decision to stop the study) Collapse << | - | Canada, British Columbia ... more >> LAIR Centre Vancouver, British Columbia, Canada, V5Z 1H2 Vancouver Prostate Centre, Gordon and Leslie Diamond Health Care Centre Vancouver, British Columbia, Canada, V5Z 1M9 GI Research Institute (G.I.R.I.) Vancouver, British Columbia, Canada, V6Z 2K5 Vancouver ID Research and Care Centre Society Vancouver, British Columbia, Canada, V6Z2C7 PerCuro Clinical Research Ltd. Victoria, British Columbia, Canada, V8V 3P9 New Zealand Auckland District Health Board Auckland, New Zealand, 1142 Christchurch Clinical Studies Trust Christchurch, New Zealand, 8011 Poland Wojewodzki Szpital Specjalistyczny im. dr Wl. Bieganskiego Lodz, Poland, 91-347 Hepid Diagnostyka I Terapia Tomasiewicz, Kiciak - Lekarze Spółka Partnerska Lublin, Poland, 20-884 ID Clinic Mysłowice, Poland, 41-400 SP ZOZ Wojewodzki Szpital Zakazny Warszawa, Poland, 01-201 EMC Instytut Medyczny SA,Przychodnia przy Lowieckiej Wroclaw, Poland, 50-220 Singapore National University Hospital Singapore, Singapore, 119074 Singapore General Hospital Singapore, Singapore, 169856 Khootech Puat Hospital Singapore, Singapore, 768828 Collapse << |
| NCT00752648 | Hepatitis C H... more >>CV Collapse << | Phase 1 | Completed | - | - |
| NCT01288742 | Hepatitis C Virus | Phase 1 | Completed | - | - |
| NCT01938625 | Hepatitis C, Chronic | Phase 2 | Completed | - | Germany ... more >> Essen, Germany Hamburg, Germany Poland Warszawa, Poland Spain Barcelona, Spain Madrid, Spain Valencia, Spain Collapse << |
| NCT01022125 | Hepatitis C Virus | Phase 1 | Completed | - | - |
| NCT02569710 | Chronic Hepatitis C | Phase 2 | Completed | - | Mauritius ... more >> CAP Research Ltd Phoenix, Mauritius Moldova, Republic of Republican Clinical Hospital Chisinau, Moldova, Republic of New Zealand Auckland Clinical Studies Auckland, New Zealand, 1150 Christchurch Clinical Studies Trust Christchurch, New Zealand, 8011 Waikato Hospital Hamilton, New Zealand P3 Research Ltd - Hawkes Bay Havelock North, New Zealand P3 Research Ltd - Wellington Wellington, New Zealand Wellington Hospital Wellington, New Zealand United Kingdom King's College Hospital Brixton, United Kingdom NHS Greater Glasgow and Clyde Glasgow Royal Infirmary Glasgow, United Kingdom Pennine Acute Hospitals Trust Oldham, United Kingdom Collapse << |
| NCT01323244 | Hepatitis C | Phase 3 | Completed | - | - |
| NCT01689623 | Healthy Participants | Phase 1 | Completed | - | United States, Nebraska ... more >> Lincoln, Nebraska, United States Collapse << |
| NCT01938625 | - | - | Completed | - | - |
| NCT01224197 | Hepatitis C | Phase 1 | Completed | - | Hong Kong ... more >> Sha Tin, Hong Kong Collapse << |
| NCT01090700 | Hepatitis C Virus | Phase 1 | Completed | - | - |
| NCT02385071 | Healthy | Phase 1 | Completed | - | United Kingdom ... more >> Harrow, United Kingdom Collapse << |
| NCT01381835 | Hepatitis C Virus | Phase 1 | Completed | - | Czech Republic ... more >> Prague 7, Czech Republic Collapse << |
| NCT01571570 | Healthy Volunteers | Phase 1 | Completed | - | United Kingdom ... more >> Harrow, United Kingdom Collapse << |
| NCT02071355 | Healthy | Phase 1 | Completed | - | China ... more >> Beijing, China Collapse << |
| NCT01628692 | Hepatitis C Virus | Phase 2 | Completed | - | United States, California ... more >> San Francisco General Hospital San Francisco, California, United States, 94110 Kaiser Permanente Med Ctr San Francisco, California, United States, 94118 United States, Indiana Indiana University Indianapolis, Indiana, United States, 46202 United States, Maryland Johns Hopkins University Lutherville, Maryland, United States, 21093 United States, Tennessee Nashville Medical Research Institute Nashville, Tennessee, United States, 37205 United States, Texas Texas Clinical Research Institute, Llc Arlington, Texas, United States, 76012 United States, Virginia Metropolitan Research Fairfax, Virginia, United States, 22031 Argentina Local Institution Buenos Aires, Argentina, 1119 Local Institution Buenos Aires, Argentina, C1181ACH France Local Institution Creteil Cedex, France, 94010 Local Institution Limoges, France, 87042 Local Institution Marseille Cedex 08, France, 13285 Local Institution Paris Cedex 13, France, 75651 Local Institution Paris Cedex 14, France, 75679 Local Institution Pessac, France, 33600 Local Institution Vandoeuvre Les Nancy, France, 54511 Germany Local Institution Berlin, Germany, 10969 Local Institution Frankfurt, Germany, 60590 Local Institution Hamburg, Germany, 20099 Local Institution Koeln, Germany, 50937 Hungary Local Institution Budapest, Hungary, 1097 Local Institution Budapest, Hungary, 1126 Local Institution Gyula, Hungary, 5700 Spain Local Institution Barcelona, Spain, 08035 Local Institution Madrid, Spain, 28046 Local Institution Valencia, Spain, 46010 Collapse << |
| NCT00915564 | Hepatitis C | Phase 1 | Completed | - | Canada ... more >> Toronto, Canada Collapse << |
| NCT02993250 | Hepatitis C, Chronic | Phase 2 | Completed | - | Japan ... more >> Amagasaki-Shi, Japan Bunkyo-Ku, Japan Hiroshima-Shi, Japan Kagoshima-Shi, Japan Kurume-Shi, Japan Musashino-Shi, Japan Nagoya-Shi, Japan Omura-Shi, Japan Osaka-Shi, Japan Saitama, Japan Sakai-Shi, Japan Sapporo-Shi, Japan Suita-Shi, Japan Yokohama-Shi, Japan Collapse << |
| NCT02945020 | Healthy | Phase 1 | Completed | - | United States, Arizona ... more >> Tempe, Arizona, United States Collapse << |
| NCT01479881 | Hepatitis C Virus | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
| NCT02349048 | - | - | Completed | - | - |
| NCT00812331 | - | - | Completed | - | - |
| NCT02349048 | Hepatitis C Virus | Phase 2 | Completed | - | United States, California ... more >> Bakersfield, California, United States United States, Florida Jacksonville, Florida, United States United States, Maryland Lutherville, Maryland, United States United States, North Carolina Winston Salem, North Carolina, United States United States, Tennessee Knoxville, Tennessee, United States United States, Texas Arlington, Texas, United States San Antonio, Texas, United States Canada, Ontario Toronto, Ontario, Canada Collapse << |
| NCT02765490 | Hepatitis C, Chronic | Phase 2 | Completed | - | Belgium ... more >> Antwerpen, Belgium Bruxelles, Belgium Edegem, Belgium Gent, Belgium Kortrijik, Belgium Leuven, Belgium Canada, British Columbia Vancouver, British Columbia, Canada Victoria, British Columbia, Canada Canada, Ontario Toronto, Ontario, Canada Vaughan, Ontario, Canada Canada, Quebec Monteral, Quebec, Canada Montreal, Quebec, Canada Germany Berlin, Germany Essen, Germany Frankfurt, Germany Hamburg, Germany Leipzig, Germany Poland Lodz, Poland Lublin, Poland Mysłowice, Poland Warszawa, Poland Wroclaw, Poland Singapore Singapore, Singapore Spain Barcelona, Spain Madrid, Spain Málaga, Spain Seville, Spain Valencia, Spain Collapse << |
| NCT01799603 | Healthy | Phase 1 | Completed | - | Japan ... more >> Toshima, Japan Collapse << |
| NCT01567735 | Hepatitis C | Phase 3 | Completed | - | Belgium ... more >> Antwerpen, Belgium Brussel, Belgium Edegem, Belgium France Clichy, France Creteil, France Lyon, France Paris, France Villejuif Cedex, France Collapse << |
| NCT02824315 | Healthy | Phase 1 | Completed | - | United Kingdom ... more >> Surrey, United Kingdom Collapse << |
| NCT01891851 | Healthy | Phase 1 | Completed | - | Belgium ... more >> Aalst, Belgium Collapse << |
| NCT02165189 | Hepatitits C | Phase 2 | Completed | - | United States, Colorado ... more >> Aurora, Colorado, United States United States, Florida Gainesville, Florida, United States Miami, Florida, United States United States, Massachusetts Boston, Massachusetts, United States United States, Michigan Ann Arbor, Michigan, United States Detroit, Michigan, United States United States, New York New York, New York, United States United States, North Carolina Durham, North Carolina, United States United States, Pennsylvania Philadelphia, Pennsylvania, United States Pittsburgh, Pennsylvania, United States United States, Texas Dallas, Texas, United States Collapse << |
| NCT02421211 | Hepatitis C, Chronic | Phase 2 | Completed | - | Belgium ... more >> Antwerpen, Belgium Brussel, Belgium Gent, Belgium Leuven, Belgium Canada, Ontario Toronto, Ontario, Canada Collapse << |
| NCT02103699 | - | - | Completed | - | - |
| NCT01907724 | Hepatitis C, Chronic | Phase 1 | Completed | - | - |
| NCT01813513 | Chronic Hepatitis C Infection | Phase 1 | Completed | - | - |
| NCT02485080 | PT-NANBH | Phase 4 | Withdrawn(Withdrawn due to lac... more >>k of resources) Collapse << | - | United States, California ... more >> Stanford University Medical Center Palo Alto, California, United States, 94304 United States, Connecticut Yale University Medical Center New Haven, Connecticut, United States, 06520 Collapse << |
| NCT01046058 | Hepatitis C Virus | Phase 1 | Completed | - | United States, California ... more >> Anaheim, California, United States United States, Florida Orlando, Florida, United States United States, Texas San Antonio, Texas, United States Collapse << |
| NCT03069001 | HCV | Phase 4 | Completed | - | - |
| NCT02421211 | - | - | Completed | - | - |
| NCT02278419 | Hepatitis C | Phase 2 | Completed | - | Egypt ... more >> Cairo, Egypt Menoufiya, Egypt Collapse << |
| NCT00812331 | Hepatitis C | Phase 2 | Completed | - | Belgium ... more >> Brugge, Belgium Brussels, Belgium Bruxelles, Belgium Gent, Belgium Leuven, Belgium Germany Berlin, Germany Frankfurt N/A, Germany Freiburg, Germany Hannover, Germany Thailand Bangkok, Thailand Chiang Mai, Thailand Collapse << |
| NCT02114177 | Hepatitis C Virus Infection | Phase 3 | Completed | - | - |
| NCT02397395 | Renal Impairment ... more >> End-stage Renal Disease Collapse << | Phase 2 | Withdrawn(Trial has been cance... more >>lled due to availability of new therapeutic options for patient population) Collapse << | May 2016 | France ... more >> Paris, France Toulouse Cedex 9, France Villejuif, France Spain Barcelona, Spain Madrid, Spain Santander, Spain Collapse << |
| NCT02262728 | Hepatitis C, Chronic | Phase 2 | Completed | - | United States, Texas ... more >> San Antonio, Texas, United States Collapse << |
| NCT02262728 | - | - | Completed | - | - |
| NCT02253550 | Chronic Hepatitis C | Phase 2 | Completed | - | United States, California ... more >> Peter J. Ruane, MD, Inc. Los Angeles, California, United States, 90036 Collapse << |
| NCT02114151 | Hepatitis C Virus Infection | Phase 3 | Completed | - | - |
| NCT02114151 | - | - | Completed | - | - |
| NCT02404805 | HIV Hepatitis... more >> C Collapse << | Not Applicable | Completed | - | United States, Colorado ... more >> University of Colorado Anschutz Medical Campus Aurora, Colorado, United States, 80045 Collapse << |
| NCT02114177 | - | - | Completed | - | - |
| NCT01707342 | Healthy Male Participants | Phase 1 | Completed | - | Belgium ... more >> Merksem, Belgium Collapse << |
| NCT02702739 | Liver Cirrhosis | Phase 4 | Completed | - | Italy ... more >> AO San Camillo Forlanini Rome, Italy, 00142 Collapse << |
| NCT02268864 | Hepatitis C, Chronic | Phase 2 | Completed | - | Belgium ... more >> Antwerpen, Belgium Brussel, Belgium Gent, Belgium France Creteil, France Lyon, France Montpellier, France Nice N/A, France Paris Cedex 12, France Paris, France Vandoeuvre Les Nancy, France Germany Frankfurt, Germany Hamburg, Germany Hannover, Germany Kiel, Germany Tübingen, Germany Würzburg, Germany Hungary Budapest, Hungary Debrecen, Hungary Spain Badalona, Spain Barcelona, Spain Santander, Spain Valencia, Spain United Kingdom Birmingham, United Kingdom London, United Kingdom Collapse << |
| NCT02268864 | - | - | Completed | - | - |
| NCT02624063 | Hepatitis C, Chronic | Phase 4 | Completed | - | Brazil ... more >> Outpatient Clinic of Viral Hepatitis (NUPAIG) São Paulo, Brazil, 04025-001 Collapse << |
| NCT02206932 | Hepatitis C, Chronic ... more >> HIV CDC Category A1 Collapse << | Phase 4 | Withdrawn | - | United States, California ... more >> San Francisco General Hospital, University of California, San Francisco San Francisco, California, United States, 94110 Collapse << |
| NCT02250807 | - | - | Completed | - | - |
| NCT02250807 | Chronic Hepatitis C ... more >> Genotype 4 Chronic Hepatitis C Collapse << | Phase 3 | Completed | - | Spain ... more >> Badalona, Spain Barcelona, Spain Madrid, Spain Santander N/A, Spain Sevilla N/A, Spain Sevilla, Spain Valencia, Spain Collapse << |
| NCT02512562 | Chronic Hepatitis C | Phase 1 | Completed | - | France ... more >> Biotrial Rennes, France Collapse << |
