CAS No.: 150374-95-1
Sivelestat sodium/西维来司钠 Catalog No. CSN17901
Synonyms: ONO5046-Na;Sodium sivelestat;EI546 sodium
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase (IC50 = 44 nM and Ki=200 nM) and also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT00219375 Acute Lung Injury ... more >> Systemic Inflammatory Response Syndrome Collapse << Phase 4 Completed - Japan ... more >> Chubu Region Facility Chubu, Japan Chugoku Region Facility Chugoku, Japan Hokkaido Region Facility Hokkaido, Japan Hokuriku Regional Facility Hokuriku, Japan Kanto Regional Facility Kanto, Japan Kinki Region Facility Kinki, Japan Kyushu Region Facility Kyushu, Japan Shikoku Region Facility Shikoku, Japan Tohoku Region Facility Tohoku, Japan Collapse << NCT01170845 Esophageal Cancer Not Applicable Completed - Japan ... more >> Chikara Kunisaki Yokohama, Kanagawa, Japan, 232-0024 Collapse << - 参考文献
- [1] Imokawa S, Mori K, et al. [Acute respiratory failure due to pneumocystis pneumonia successfully treated with combined use of sivelestat sodium hydrate] . Nihon Kokyuki Gakkai Zasshi. 2008 Jun;46(6):461-5. Japanese.
- [2] Kawabata K, Suzuki M, et al. ONO-5046, a novel inhibitor of human neutrophil elastase. Biochem Biophys Res Commun. 1991 Jun 14;177(2):814-20.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 150374-95-1 | 储存条件 |
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| 分子式 | C20H21N2NaO7S | 运输 | 蓝冰 | |
| 分子量 | 456.44 | 别名 | ONO5046-Na;Sodium sivelestat;EI546 sodium;LY544349 sodium;ONO-5046 Sodium;西维来司钠 |
