CAS No.: 145572-44-7
Sophocarpine monohydrate/槐果碱水合物 Catalog No. CSN17136
Synonyms: Sophoridine hydrate;Sophoridin;L-Sophoridine
Sophocarpine, a natural product isolated and purified from the herb of Sophora alopecuroidos L., with anti-viral, anti-cachectic and anti-inflammatory effects, can alleviate liver fibrosis mainly by inhibiting the TLR4 pathway, it may be a potential chemotherapeutic agent for chronic liver diseases, ameliorate the ischemic injury induced by transient focal cerebral ischemia in rats and that this neuroprotective effect may be related to the anti-ASIC1 channel and anti-apoptotic action of sophocarpine, and also alleviate hepatocyte steatosis and the potential mechanism may be the activated signaling pathway of AMPK.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Qian H, Shi J, et al. Sophocarpine attenuates liver fibrosis by inhibiting the TLR4 signaling pathway in rats. World J Gastroenterol. 2014 Feb 21;20(7):1822-32.
- [2] Song CY, Shi J, et al. Sophocarpine alleviates hepatocyte steatosis through activating AMPK signaling pathway. Toxicol In Vitro. 2013 Apr;27(3):1065-71.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 145572-44-7 | 储存条件 |
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| 分子式 | C15H24N2O2 | 运输 | 蓝冰 | |
| 分子量 | 264.36 | 别名 | Sophoridine hydrate;Sophoridin;L-Sophoridine;5-Epidihydrosophocarpine;槐果碱水合物 |
