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CAS No.: 502487-67-4

SQ109 Catalog No. CSN18304

Synonyms: NSC 722041

SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM.

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描述SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM.
临床研究

NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
NCT01785186	Tuberculosis, Pulmonary	Phase 2	Completed	-	South Africa ... more >> TASK Applied Science Bellville, South Africa, 7530 University of Cape Town, Centre for Tuberculosis Research Innovation Cape Town, South Africa, 7700 Wits Health Consortium Johannesburg, South Africa, 2092 The Aurum Institute for Health Research Johannesburg, South Africa, 2193 Tanzania Ifakara Health Institute Bagamoyo, Tanzania, P.O.Box 74 NIMR - Mbeya Medical Research Programme Mbeya, Tanzania, P.O. Box 2410 Kilimanjaro Christian Medical Centre (KCMC) / Kilimanjaro Clinical Research Institute (KCRI) (with affiliated field sites such as Kibong'oto National Tuberculosis Hospital Same, Mererani, Chekereni and Mawenzi Regional Hospital) Moshi, Tanzania, 2236 Collapse <<
NCT00866190	TB Multi-drug Resistant	Phase 1	Completed	-	United States, Kansas ... more >> Quintiles Phase I Services Overland Park, Kansas, United States, 66211 Collapse <<
NCT01785186	-	-	Completed	-	-

更多
参考文献

[1] Veiga-Santos P, Li K, et al. SQ109, a new drug lead for Chagas disease. Antimicrob Agents Chemother. 2015 Apr;59(4):1950-61.
[2] Jia L, Tomaszewski JE, et al. Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol. 2005 Jan;144(1):80-7.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 3.0253 mL
- 15.1263 mL
- 30.2526 mL
- 5 mM
- 0.6051 mL
- 3.0253 mL
- 6.0505 mL
- 10 mM
- 0.3025 mL
- 1.5126 mL
- 3.0253 mL

技术信息

CAS号	502487-67-4		储存条件	粉末 Keep in dark place,Sealed in dry,2-8°C 液体 -20°C:3-6 月 -80°C:12月
分子式	C22H38N2		运输	蓝冰
分子量	330.55		别名	NSC 722041

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NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点

NCT01785186	Tuberculosis, Pulmonary	Phase 2	Completed	-	South Africa ... more >> TASK Applied Science Bellville, South Africa, 7530 University of Cape Town, Centre for Tuberculosis Research Innovation Cape Town, South Africa, 7700 Wits Health Consortium Johannesburg, South Africa, 2092 The Aurum Institute for Health Research Johannesburg, South Africa, 2193 Tanzania Ifakara Health Institute Bagamoyo, Tanzania, P.O.Box 74 NIMR - Mbeya Medical Research Programme Mbeya, Tanzania, P.O. Box 2410 Kilimanjaro Christian Medical Centre (KCMC) / Kilimanjaro Clinical Research Institute (KCRI) (with affiliated field sites such as Kibong'oto National Tuberculosis Hospital Same, Mererani, Chekereni and Mawenzi Regional Hospital) Moshi, Tanzania, 2236 Collapse <<
NCT00866190	TB Multi-drug Resistant	Phase 1	Completed	-	United States, Kansas ... more >> Quintiles Phase I Services Overland Park, Kansas, United States, 66211 Collapse <<
NCT01785186	-	-	Completed	-	-
NCT01252108	Helicobacter Pylori Infection	Phase 2	Withdrawn(lack of funding)	-	-
NCT01585636	Tuberculosis	Phase 1	Completed	-	United States, Kansas ... more >> Quintiles Phaes 1 Clinical Study Unit Lenexa, Kansas, United States, 66219 Collapse <<
NCT01874314	Tuberculosis	Phase 1	Withdrawn	December 2015	United States, Ohio ... more >> Case Western Reserve University - Case Medical Center - Infectious Disease & HIV Medicine Cleveland, Ohio, United States, 44106-1716 Collapse <<
NCT01218217	Tuberculosis, Pulmonary	Phase 2	Completed	-	South Africa ... more >> TASK Applied Sciences Cape Town, South Africa University of Cape Town Cape Town, South Africa Collapse <<
NCT01358162	Tuberculosis	Phase 1	Completed	-	United States, Kansas ... more >> Quintiles Phase I Services - Overland Park Overland Park, Kansas, United States, 66211 Collapse <<

总药量计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 动物数量只每天给药次给药天

需要的总药量：mg

工作液计算器 ✕

动物实验：给药剂量mg/kg 动物体重g 给药体积μL

您需要配制的工作液浓度为：mg/mL

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