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CAS No.: 2254693-15-5
SRX3207 is an orally active dual Syk/PI3K inhibitor with IC50 value of 30nM for Syk. It potently blocks phosphorylation of Syk at 348 site and Y525/526 site. SRX3207 reduced immunosuppressive macrophage polarization and increased infiltration and cytotoxicity of CD8+ T cells in LLC tumors and increased expression of Ifng and Gzmb in 3207 treated LLC tumors.
实验方案
技术信息
CAS号 | 2254693-15-5 | 储存条件 |
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分子式 | C29H29N7O3S | 运输 | 蓝冰 | |
分子量 | 555.65 | 别名 |
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