400-920-2911 sales@csnpharm.cn
您的位置 : 首页 / JAK/STAT Signaling / STAT / STAT5-IN-1/Stat5抑制剂
CAS No.: 285986-31-4
Synonyms: STAT5 Inhibitor;Signal Transducers and Activators of Transcription 5;MDK-6314
STAT5 inhibitor suppresses STAT5 via interaction of its SH2 domain with IC50 of 47 µM.
生物活性
靶点 | STAT5 IC50:47µM |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01927120 | Graft-Versus-Host-Disease | Phase 2 | Completed | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Collapse << |
NCT01927120 | - | - | Completed | - | - |
NCT01162551 | Cancer Leukem... more >>ia Lymphoma Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 Collapse << |
实验方案
技术信息
CAS号 | 285986-31-4 | 储存条件 |
|
|||||
分子式 | C16H11N3O3 | 运输 | 蓝冰 | |||||
分子量 | 293.28 | 别名 | STAT5 Inhibitor;Signal Transducers and Activators of Transcription 5;MDK-6314 | |||||
溶解度 |
|
动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01927120 | Graft-Versus-Host-Disease | Phase 2 | Completed | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612 Collapse << |
NCT01927120 | - | - | Completed | - | - |
NCT01162551 | Cancer Leukem... more >>ia Lymphoma Collapse << | Phase 2 | Completed | - | United States, Pennsylvania ... more >> The Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104 Collapse << |
NCT00671203 | Colon Ischemia ... more >> Aortic Aneurysm Collapse << | Phase 3 | Completed | - | United States, California ... more >> University of California at Davis Medical Center Davis, California, United States, 95817 Stanford University Vascular Surgery Palo Alto, California, United States, 94305 Collapse << |
NCT02888964 | Leukemia, Myeloid, Chronic-Pha... more >>se Collapse << | Phase 2 | Completed | - | France ... more >> CHR Annecy Annecy, France Institut Bergonié Bordeaux, France CH Versailles Le Chesnay, France CHU Lille Lille, France IPC Marseille, France CHU archet 1 Nice, France St Louis Paris, France CHU Poitiers Poitiers, France CHU Purpan Toulouse, France Collapse << |
NCT01150955 | Metabolic Syndrome ... more >> Obesity Collapse << | Not Applicable | Completed | - | Denmark ... more >> Aarhus University Hospital, Department of Endocrinology, MEA Aarhus, Denmark, 8000 Collapse << |
NCT02605746 | Glioblastoma ... more >>Brain Metastases Collapse << | Early Phase 1 | Unknown | September 2017 | United States, Arizona ... more >> Barrow Brain and Spine Recruiting Phoenix, Arizona, United States, 85013 Contact: Norissa Honea, RN, PhD 602-406-6267 norissa.honea@dignityhealth.org Principal Investigator: Nader Sanai, MD Collapse << |
NCT02532010 | - | - | Terminated(The study was put o... more >>n clinical hold by the sponsor since Feb 9th 2016, and was later decided not to re-open due to financial constraints.) Collapse << | - | - |
NCT02532010 | Acute Myeloid Leukemia (AML) | Phase 2 | Terminated(The study was put o... more >>n clinical hold by the sponsor since Feb 9th 2016, and was later decided not to re-open due to financial constraints.) Collapse << | - | United States, New York ... more >> Weill Cornell Medical College New York, New York, United States, 10021 Collapse << |
NCT01431664 | Leukemia | Phase 1 | Completed | - | United Kingdom ... more >> Royal Marsden Hospital Surrey, London, United Kingdom, SM2 5PT Birmingham Children's Hospital Birmingham,, United Kingdom, B4 6NH Leeds General Infirmary Leeds, United Kingdom, LS1 3EX Royal Manchester Children's Hospital Manchester, United Kingdom, M13 9WL Great North Children's Hospital, Royal Victoria Infirmary Newcastle upon Tyne, United Kingdom, NE1 4LP Collapse << |
NCT02713581 | - | - | Recruiting | January 3, 2020 | France ... more >> CHRU de Montpellier - Hôpital Saint-Eloi Not yet recruiting Montpellier cedex 5, France, 34295 Principal Investigator: Isabelle Quéré, MD, PhD Sub-Investigator: Jean-Philippe Galanaud, MD CHRU de Nîmes - Hôpital Universitaire Carémeau Recruiting Nîmes Cedex 09, France, 30029 Principal Investigator: Sylvie Bouvier, MD Sub-Investigator: Jean-Christophe Gris, MD, PhD Sub-Investigator: Géraldine Lavigne, MD Sub-Investigator: Eva Nouvellon, MD Sub-Investigator: Erick Mercier, MD Collapse << |
靶点 | Description | IC50 |
---|---|---|
STAT5 | IC50:47µM |
联系我们
官方电话:400-920-2911
二维码
微信公众号 CSN官网