CAS No.: 326914-10-7
SU11652 Catalog No. CSN20166
SU11652 is a sunitinib analog with anti-tyrosine-kinase activity, also is identified as a potential inhibitor for Leishmania major (Lm) nucleoside diphosphate kinases NDK and structural studies indicated that this molecule binds to the active site of LmNDK in a similar conformation to nucleotides, mimicking natural substrates.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Ellegaard AM, Groth-Pedersen L, et al. Sunitinib and SU11652 inhibit acid sphingomyelinase, destabilize lysosomes, and inhibit multidrug resistance. Mol Cancer Ther. 2013 Oct;12(10):2018-30.
- [2] Guo Y, Chen Y, et al. SU11652 Inhibits tyrosine kinase activity of FLT3 and growth of MV-4-11 cells. J Hematol Oncol. 2012 Dec 6;5:72.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 326914-10-7 | 储存条件 |
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| 分子式 | C22H27ClN4O2 | 运输 | 蓝冰 | |
| 分子量 | 414.93 | 别名 |
