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CAS No.: 309915-12-6
Synonyms: SCIO-469 hydrochloride;SCIO-469;Talmapimod
Talmapimod, also known as SCIO-469, is an orally bioavailable, small-molecule, p38 mitogen-activated protein kinase (MAPK) inhibitor with potential immunomodulating, anti-inflammatory, and antineoplastic activities. Talmapimod specifically binds to and inhibits the phosphorylation of p38 MAPK, which may result in the induction of tumor cell apoptosis, the inhibition of tumor cell proliferation, and the inhibition of tumor angiogenesis. This agent may also enhance proteasome inhibitor-induced apoptosis.
生物活性
实验方案
技术信息
CAS号 | 309915-12-6 | 储存条件 |
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分子式 | C27H31Cl2FN4O3 | 运输 | 蓝冰 | |
分子量 | 549.46 | 别名 | SCIO-469 hydrochloride;SCIO-469;Talmapimod;Talmapimod HCl |
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