CAS No.: 1025007-04-8
TC-6683 Catalog No. CSN20387
Synonyms: TC-6683
AZD1446 is a highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01044342 Cognition Phase 1 Completed - France ... more >> Research Site Rouffach, France Collapse << NCT01092299 Healthy Phase 1 Completed - Sweden ... more >> Research Site Lulea, Sweden Research Site Uppsala, Sweden Collapse << NCT01039701 Mild to Moderate Alzheimer's D... more >>isease Collapse << Phase 2 Completed - Czech Republic ... more >> Research Site Litomerice, Czech Republic Research Site Praha 10 - Strasnice, Czech Republic Research Site Praha 10, Czech Republic Research Site Praha 6, Czech Republic Hungary Research Site Debrecen, Hungary Research Site Esztergom, Hungary Research Site Miskolc, Hungary Research Site Nagykallo, Hungary Research Site Nyiregyhaza, Hungary Research Site Szeged, Hungary Slovakia Research Site Bratislava, Slovakia Research Site Roznava, Slovakia Research Site Zlate Moravce, Slovakia Collapse << - 更多
- 参考文献
- [1] Zimmerman CN, Eskow Jaunarajs KL, et al. Evaluation of AZD1446 as a Therapeutic in DYT1 Dystonia. Front Syst Neurosci. 2017 Jun 13;11:43.
- [2] Mazurov AA, Miao L, et al. Discovery of 3-(5-chloro-2-furoyl)-3,7-diazabicyclo[3.3.0] octane (TC-6683, AZD1446), a novel highly selective α4β2 nicotinic acetylcholine receptor agonist for the treatment of cognitive disorders. J Med Chem. 2012 Nov 8;55(21):9181-94.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1025007-04-8 | 储存条件 |
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| 分子式 | C11H13ClN2O2 | 运输 | 蓝冰 | |
| 分子量 | 240.69 | 别名 | TC-6683 |
