CAS No.: 1005775-56-3
TC ASK 10 Catalog No. CSN23144
Synonyms: ASK1 Inhibitor 10
ASK1 Inhibitor 10 is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1). It is selective for ASK1 over ASK2 as well as MEKK1, TAK-1, IKKβ, ERK1, JNK1, p38α, GSK3β, PKCθ, and B-RAF. It inhibits streptozotocin-induced increases in JNK and p38 phosphorylation in INS-1 pancreatic β cells in a concentration-dependent manner.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT03696446 Coronary Heart Disease Not Applicable Recruiting December 31, 2020 Canada, Ontario ... more >> University of Ottawa Heart Institute Recruiting Ottawa, Ontario, Canada, K1Y 4W7 Contact: Evyanne Wooding 613-696-7000 ext 17596 ewooding@ottawaheart.ca Collapse << NCT02267096 Smoking Lung ... more >>Cancer Collapse << Phase 3 Completed - United States, District of Col... more >>umbia Georgetown University Medical Center Washington, District of Columbia, United States, 20007 United States, Massachusetts Lahey Hospital and Medical Center Burlington, Massachusetts, United States, 01805 United States, New Jersey Hackensack University Medical Center Hackensack, New Jersey, United States, 07601 Collapse << NCT03107247 Skeletal Injury Phase 4 Enrolling by invitation March 31, 2021 United States, Massachusetts ... more >> Boston Children's Hospital Boston, Massachusetts, United States, 02115 Collapse <<
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1005775-56-3 | 储存条件 |
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| 分子式 | C21H23Cl2N5O | 运输 | 蓝冰 | |
| 分子量 | 432.35 | 别名 | ASK1 Inhibitor 10 |
