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CAS No.: 63074-08-8
Synonyms: Terazosin;Hytrin;Zayasel
Terazosin HCl is a selective antagonist for alpha-adrenergic receptor, used for treatment for hypertension and prostate enlargement (BPH) through lowering the blood pressure with elimination half-life of 12 hours.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
NCT03339258 | Stress Disorders, Post-Traumat... more >>ic Collapse << | Phase 2 | Recruiting | June 2021 | United States, California ... more >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Contact: Andrew Levihn-Coon, B.A. 415-221-4810 ext 23809 andrew.levihn-coon@va.gov Collapse << |
NCT01323998 | - | - | Completed | - | - |
实验方案
技术信息
CAS号 | 63074-08-8 | 储存条件 |
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分子式 | C19H26ClN5O4 | 运输 | 蓝冰 | |||||
分子量 | 423.89 | 别名 | Terazosin;Hytrin;Zayasel;Terazosine;Flumarc;Fosfomic;Blavin;Fosfomic HCl;Terazosin (hydrochloride);Terazocin HCl;Vasocard;Hyprin;A-45975;盐酸特拉唑嗪 | |||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
NCT03339258 | Stress Disorders, Post-Traumat... more >>ic Collapse << | Phase 2 | Recruiting | June 2021 | United States, California ... more >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Contact: Andrew Levihn-Coon, B.A. 415-221-4810 ext 23809 andrew.levihn-coon@va.gov Collapse << |
NCT01323998 | - | - | Completed | - | - |
NCT00000620 | - | - | Completed | - | - |
NCT00684489 | Hypertension | Not Applicable | Completed | - | - |
NCT01323998 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
NCT03653845 | Primary Aldosteronism ... more >> Hypertension Collapse << | Phase 3 | Recruiting | January 1, 2020 | China, Chongqing ... more >> The third hospital affiliated to the Third Military Medical University Recruiting Chongqing, Chongqing, China, 400042 Contact: Hongbo He, MD. 86-23-68757880 cqhehongbo@gmail.com Principal Investigator: Zhiming Zhu, MD. China The third hospital affiliated to the Third Military Medical University Recruiting Chongqing, China, 400042 Contact: Zhiming Zhu, MD, PhD 86-023-68705094 zhuzm@yahoo.com Principal Investigator: Zhiming Zhu, MD, PhD Collapse << |
NCT01386983 | - | - | Completed | - | - |
NCT01332435 | - | - | Completed | - | - |
NCT01218243 | Benign Prostatic Hyperplasia (... more >>BPH) Collapse << | Phase 2 | Completed | - | China ... more >> Guang'an Men Hospotal Affiliated to China Academy of Chinese Medical Sciences Beijing, China, 100053 Collapse << |
NCT01390870 | - | - | Completed | - | - |
NCT01332435 | - | - | Completed | - | - |
NCT02966717 | Renal Insufficiency, Chronic ... more >> Nephrotic Syndrome Collapse << | Phase 2 | Active, not recruiting | October 2021 | China, Guangdong ... more >> Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China, 510282 Collapse << |
NCT01390870 | - | - | Completed | - | - |
NCT01218243 | - | - | Completed | - | - |
NCT01386983 | - | - | Completed | - | - |
NCT01435954 | - | - | Completed | - | - |
NCT00438113 | Atrial Fibrillation | Phase 4 | Completed | - | Canada, Nova Scotia ... more >> QE II Health Sciences Centre Halifax, Nova Scotia, Canada, B3H 3A7 Collapse << |
NCT02244333 | - | - | Completed | - | - |
NCT00700583 | Nocturia | Not Applicable | Completed | - | Korea, Republic of ... more >> Department of Urology, Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Collapse << |
NCT02046395 | Type 2 Diabetes ... more >> Hypertension Collapse << | Phase 4 | Recruiting | December 2019 | United States, Louisiana ... more >> Tulane University Health Sciences Center Recruiting New Orleans, Louisiana, United States, 70112 Contact: Bonnie L Katalenich, MPH 504-988-0200 bkatalen@tulane.edu Principal Investigator: Tina Thethi, MD, MPH Collapse << |
NCT01508637 | Cardiovascular Effects | Not Applicable | Unknown | December 2015 | United States, Washington ... more >> University of Washington Medical Center Recruiting Seattle, Washington, United States, 98195 Collapse << |
NCT00687388 | Benign Prostatic Hyperplasia | Phase 4 | Withdrawn(in order to prepare ... more >>a new clinical trial to evaluate with pathological change) Collapse << | - | Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Samsung Medical Center Seoul, Korea, Republic of, 135-710 Asan Medical Center Seoul, Korea, Republic of, 138-736 Collapse << |
NCT00693199 | Lower Urinary Tract Symptoms ... more >> Hypertension Collapse << | Not Applicable | Completed | - | China, Anhui ... more >> Biomedicine Inistitute of Anhui Medical University Hefei, Anhui, China, 230032 Collapse << |
NCT01530243 | Disorder of Urinary Stent | Phase 2 Phase 3 | Completed | - | Iran, Islamic Republic of ... more >> Imam Khomeini Hospital Urmia, Azerbaijan-gharbi, Iran, Islamic Republic of Collapse << |
NCT00563485 | Prostatic Hyperplasia ... more >> Urinary Retention Collapse << | Not Applicable | Terminated | - | China ... more >> Prince of Wales Hospital Hong Kong, China Collapse << |
NCT01366664 | Ejaculation | Phase 1 | Completed | - | United States, Alabama ... more >> Anniston, Alabama, United States United States, Arizona Tempe, Arizona, United States United States, California Costa Mesa, California, United States United States, Florida Miramar, Florida, United States United States, Tennessee Knoxville, Tennessee, United States United States, Texas Dallas, Texas, United States Collapse << |
NCT03195673 | Carotid Artery Stenosis | Phase 2 | Recruiting | December 15, 2019 | China, Beijing ... more >> Beijing Anzhen Hospital Recruiting Beijing, Beijing, China, 100029 Contact: He Yin, MD The Luhe Teaching Hospital of the Capital Medical University Recruiting Beijing, Beijing, China, 101100 Contact: Xiaokun Geng, MD Collapse << |
NCT02244255 | Prostatic Hyperplasia | Phase 4 | Completed | - | - |
NCT00237510 | Antidepressant Induced Excessi... more >>ve Sweating Collapse << | Not Applicable | Completed | - | United States, Pennsylvania ... more >> Thomas Jefferson University Department of Psychiatry and Human Behavior Philadelphia, Pennsylvania, United States, 19107 Collapse << |
NCT00449683 | Hyperhidrosis | Phase 4 | Completed | - | United States, Pennsylvania ... more >> Thomas Jefferson University, Department of Psychiatry Philadelphia, Pennsylvania, United States, 19107 Collapse << |
NCT01530243 | - | - | Completed | - | - |
NCT00000620 | Atherosclerosis ... more >> Cardiovascular Diseases Hypercholesterolemia Hypertension Diabetes Mellitus, Type 2 Diabetes Mellitus Coronary Disease Collapse << | Phase 3 | Completed | - | United States, Minnesota ... more >> Minneapolis Medical Research Foundation Minneapolis, Minnesota, United States, 55404 United States, New York Columbia University New York, New York, United States, 10027 United States, North Carolina Wake Forest University Winston-Salem, North Carolina, United States, 27106 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Tennessee Veterans Affairs Memphis, Tennessee, United States, 38104 United States, Washington University of Washington Seattle, Washington, United States, 98195 Canada, Ontario McMaster University Hamilton, Ontario, Canada Collapse << |
NCT03339258 | Stress Disorders, Post-Traumat... more >>ic Collapse << | Phase 2 | Recruiting | June 2021 | United States, California ... more >> San Francisco VA Medical Center Recruiting San Francisco, California, United States, 94121 Contact: Andrew Levihn-Coon, B.A. 415-221-4810 ext 23809 andrew.levihn-coon@va.gov Collapse << |
NCT00000620 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
NCT01323998 | - | - | Completed | - | - |
NCT01332487 | - | - | Completed | - | - |
NCT01332435 | - | - | Completed | - | - |
NCT01332435 | - | - | Completed | - | - |
NCT00684489 | Hypertension | Not Applicable | Completed | - | - |
NCT03653845 | Primary Aldosteronism ... more >> Hypertension Collapse << | Phase 3 | Recruiting | January 1, 2020 | China, Chongqing ... more >> The third hospital affiliated to the Third Military Medical University Recruiting Chongqing, Chongqing, China, 400042 Contact: Hongbo He, MD. 86-23-68757880 cqhehongbo@gmail.com Principal Investigator: Zhiming Zhu, MD. China The third hospital affiliated to the Third Military Medical University Recruiting Chongqing, China, 400042 Contact: Zhiming Zhu, MD, PhD 86-023-68705094 zhuzm@yahoo.com Principal Investigator: Zhiming Zhu, MD, PhD Collapse << |
NCT01386983 | - | - | Completed | - | - |
NCT01386983 | - | - | Completed | - | - |
NCT01218243 | Benign Prostatic Hyperplasia (... more >>BPH) Collapse << | Phase 2 | Completed | - | China ... more >> Guang'an Men Hospotal Affiliated to China Academy of Chinese Medical Sciences Beijing, China, 100053 Collapse << |
NCT01323998 | - | - | Completed | - | - |
NCT01218243 | - | - | Completed | - | - |
NCT01390870 | - | - | Completed | - | - |
NCT01390870 | - | - | Completed | - | - |
NCT00438113 | Atrial Fibrillation | Phase 4 | Completed | - | Canada, Nova Scotia ... more >> QE II Health Sciences Centre Halifax, Nova Scotia, Canada, B3H 3A7 Collapse << |
NCT00687388 | Benign Prostatic Hyperplasia | Phase 4 | Withdrawn(in order to prepare ... more >>a new clinical trial to evaluate with pathological change) Collapse << | - | Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Samsung Medical Center Seoul, Korea, Republic of, 135-710 Asan Medical Center Seoul, Korea, Republic of, 138-736 Collapse << |
NCT02966717 | Renal Insufficiency, Chronic ... more >> Nephrotic Syndrome Collapse << | Phase 2 | Active, not recruiting | October 2021 | China, Guangdong ... more >> Zhujiang Hospital, Southern Medical University Guangzhou, Guangdong, China, 510282 Collapse << |
NCT01435954 | - | - | Completed | - | - |
NCT02244333 | - | - | Completed | - | - |
NCT00700583 | Nocturia | Not Applicable | Completed | - | Korea, Republic of ... more >> Department of Urology, Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Collapse << |
NCT01508637 | Cardiovascular Effects | Not Applicable | Unknown | December 2015 | United States, Washington ... more >> University of Washington Medical Center Recruiting Seattle, Washington, United States, 98195 Collapse << |
NCT02046395 | Type 2 Diabetes ... more >> Hypertension Collapse << | Phase 4 | Recruiting | December 2019 | United States, Louisiana ... more >> Tulane University Health Sciences Center Recruiting New Orleans, Louisiana, United States, 70112 Contact: Bonnie L Katalenich, MPH 504-988-0200 bkatalen@tulane.edu Principal Investigator: Tina Thethi, MD, MPH Collapse << |
NCT01530243 | Disorder of Urinary Stent | Phase 2 Phase 3 | Completed | - | Iran, Islamic Republic of ... more >> Imam Khomeini Hospital Urmia, Azerbaijan-gharbi, Iran, Islamic Republic of Collapse << |
NCT01530243 | - | - | Completed | - | - |
NCT00563485 | Prostatic Hyperplasia ... more >> Urinary Retention Collapse << | Not Applicable | Terminated | - | China ... more >> Prince of Wales Hospital Hong Kong, China Collapse << |
NCT03195673 | Carotid Artery Stenosis | Phase 2 | Recruiting | December 15, 2019 | China, Beijing ... more >> Beijing Anzhen Hospital Recruiting Beijing, Beijing, China, 100029 Contact: He Yin, MD The Luhe Teaching Hospital of the Capital Medical University Recruiting Beijing, Beijing, China, 101100 Contact: Xiaokun Geng, MD Collapse << |
NCT00693199 | Lower Urinary Tract Symptoms ... more >> Hypertension Collapse << | Not Applicable | Completed | - | China, Anhui ... more >> Biomedicine Inistitute of Anhui Medical University Hefei, Anhui, China, 230032 Collapse << |
NCT02244255 | Prostatic Hyperplasia | Phase 4 | Completed | - | - |
NCT00449683 | Hyperhidrosis | Phase 4 | Completed | - | United States, Pennsylvania ... more >> Thomas Jefferson University, Department of Psychiatry Philadelphia, Pennsylvania, United States, 19107 Collapse << |
NCT01366664 | Ejaculation | Phase 1 | Completed | - | United States, Alabama ... more >> Anniston, Alabama, United States United States, Arizona Tempe, Arizona, United States United States, California Costa Mesa, California, United States United States, Florida Miramar, Florida, United States United States, Tennessee Knoxville, Tennessee, United States United States, Texas Dallas, Texas, United States Collapse << |
NCT00237510 | Antidepressant Induced Excessi... more >>ve Sweating Collapse << | Not Applicable | Completed | - | United States, Pennsylvania ... more >> Thomas Jefferson University Department of Psychiatry and Human Behavior Philadelphia, Pennsylvania, United States, 19107 Collapse << |
靶点 | Description | IC50 |
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