|延胡索乙素盐酸盐|CsnPharm

CAS No.: 6024-85-7

Tetrahydropalmatine HCl/延胡索乙素盐酸盐 Catalog No. CSN22101

Synonyms: DL-Tetrahydropalmatine hydrochloride;Gindarine HCl;1-Tetrahydropalmitine HCl

Tetrahydropalmatine inhibits the LPSinduced production of COX-2 protein and mRNA in a dose-dependent manner.

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400-920-2911

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实验方案

技术信息

生物活性

描述Tetrahydropalmatine inhibits the LPSinduced production of COX-2 protein and mRNA in a dose-dependent manner. It suppresses activation of the NF-kB signaling pathway, which results in regulation of IL-8 expression and specifically blocks the ERK1=2 and p38 MAPK signaling pathways. L-THP results in p53 independent apoptosis via down-regulating XIAP protein by inhibiting MDM2 associated with proteasome-dependent pathway and increased sensitivity of EU-4 cells against doxorubicin. L-THP causes activation of caspase and resulted in apoptosis. l-THP possesses a blocking effect on dopamine D1 and D2 receptors and voltage-sensitive Ca2+ channels.

实验方案

计算器摩尔计算器总药量计算器工作液计算器
储存液制备
- 1 mg
- 5 mg
- 10 mg
- 1 mM
- 2.5517 mL
- 12.7587 mL
- 25.5175 mL
- 5 mM
- 0.5103 mL
- 2.5517 mL
- 5.1035 mL
- 10 mM
- 0.2552 mL
- 1.2759 mL
- 2.5517 mL

技术信息

CAS号

6024-85-7

储存条件

粉末: Keep in dark place,Inert atmosphere,Room temperature

液体: -20°C:3-6 月 -80°C:12月

分子式

C21H26ClNO4

运输

蓝冰

分子量

391.89

别名

DL-Tetrahydropalmatine hydrochloride;Gindarine HCl;1-Tetrahydropalmitine HCl;延胡索乙素盐酸盐

溶解度

DMSO	insoluble
Water	insoluble

动物实验配方

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Tetrahydropalmatine HCl/延胡索乙素盐酸盐 Catalog No. CSN22101

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