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CAS No.: 64461-82-1
Synonyms: DS 103-282;Tizanidine (hydrochloride);BRN-0618691
Tiamenidine HCl is a centrally-acting α1 and α2 adrenergic receptor antagonist with IC50 4.85 μM and 0.0091 μM, respectively, for the management of essential hypertension.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT02403687 | - | - | Completed | - | - |
NCT01753882 | Spinal Cord Injury | Phase 1 | Unknown | July 2017 | United States, Illinois ... more >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 Collapse << |
NCT02853240 | Cerebral Palsy | Not Applicable | Recruiting | April 2020 | France ... more >> Hôpital Femme Mère Enfant Recruiting Bron, France, 69500 Contact: Claire MIETTON, MD (0)4 72 12 95 04 ext +33 claire.mietton@chu-lyon.fr Contact: Tiphanie GINHOUX, CRA (0)4 72 35 72 31 ext +33 tiphanie.ginhoux@chu-lyon.fr Collapse << |
实验方案
技术信息
CAS号 | 64461-82-1 | 储存条件 |
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分子式 | C9H9Cl2N5S | 运输 | 蓝冰 | |||||||
分子量 | 290.17 | 别名 | DS 103-282;Tizanidine (hydrochloride);BRN-0618691;AB 021 ;AN 021;Tizanidine;Sirdalud;Ternelin;盐酸替扎尼定 | |||||||
溶解度 |
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动物实验配方 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT02403687 | - | - | Completed | - | - |
NCT01753882 | Spinal Cord Injury | Phase 1 | Unknown | July 2017 | United States, Illinois ... more >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 Collapse << |
NCT02853240 | Cerebral Palsy | Not Applicable | Recruiting | April 2020 | France ... more >> Hôpital Femme Mère Enfant Recruiting Bron, France, 69500 Contact: Claire MIETTON, MD (0)4 72 12 95 04 ext +33 claire.mietton@chu-lyon.fr Contact: Tiphanie GINHOUX, CRA (0)4 72 35 72 31 ext +33 tiphanie.ginhoux@chu-lyon.fr Collapse << |
NCT01244113 | Cerebral Palsy | Not Applicable | Completed | - | Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Collapse << |
NCT02907775 | Muscle Spasticity ... more >> Stroke Collapse << | Not Applicable | Recruiting | November 30, 2018 | United Kingdom ... more >> Sheffield Teaching Hospitals NHS FT Recruiting Sheffield, United Kingdom Contact: Alisha Patel alisha.patel@sth.nhs.uk Collapse << |
NCT01788969 | Spinal Cord Injury | Phase 1 | Unknown | December 2017 | United States, Illinois ... more >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 Collapse << |
NCT02887534 | Acute Muscle Pain | Phase 2 | Withdrawn | December 2017 | - |
NCT03068897 | Low Back Pain | Phase 4 | Completed | - | United States, New York ... more >> Montefiore Medical Center Bronx, New York, United States, 10467 Collapse << |
NCT01547234 | - | - | Completed | - | Israel ... more >> Multiple Sclerosis Center Carmel Medical Center Haifa, Israel Collapse << |
NCT00287157 | Traumatic Brain Injury | Phase 1 | Completed | - | Israel ... more >> Alyn Hospital Pediatric and Adolescent Rehabilitation Center Jerusalem, Israel, 01090 Collapse << |
NCT00430196 | Upper Limb Spasticity | Phase 4 | Completed | - | - |
NCT01068847 | Drug Dependence | Phase 1 | Completed | - | United States, Arkansas ... more >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 Collapse << |
NCT01979510 | Low Back Pain | Phase 3 | Withdrawn | May 2014 | - |
NCT00358293 | Muscle Spasticity | Phase 1 Phase 2 | Completed | - | Israel ... more >> Tel Aviv Sourasky Medical Center- Neurology Department Tel Aviv, Israel Collapse << |
NCT01844674 | Malignant Melanoma, Neoplasms | Phase 1 | Completed | - | United States, California ... more >> Diablo Valley Oncology and Hematology Pleasant Hill, California, United States, 94523 United States, Michigan Karmanos Cancer Center Detroit, Michigan, United States, 48201 United States, North Carolina Duke University Health Systems Durham, North Carolina, United States, 27710 Brazil Instituto Nacional do Cancer - INCA Rio de Janeiro, RJ, Brazil, 20560-120 Hospital de Caridade de Ijui; Oncologia Ijui, RS, Brazil, 98700-000 CITO - Centro Integrado de Terapia Onco-Hematológica - Hospital da Cidade de Passo Fundo Passo Fundo, RS, Brazil, 99010-260 Hospital Sao Lucas - PUCRS Porto Alegre, RS, Brazil, 90610-000 Canada, Quebec CSSS champlain - Charles-Le Moyne Greenfield Park, Quebec, Canada, J4V 2H1 Cyprus Bank of Cyprus Oncology Center Nicosia, Cyprus, 2006 Korea, Republic of Severance Hospital, Yonsei University Health System Seoul, Korea, Republic of, 03722 Samsung Medical Center Seoul, Korea, Republic of, 06351 Asan Medical Center. Seoul, Korea, Republic of, 138-736 Collapse << |
NCT00047580 | Multiple Sclerosis ... more >> Muscle Spasticity Spinal Cord Injury Stroke Collapse << | Phase 3 | Completed | - | United States, Arizona ... more >> Radiant Research Tucson, Arizona, United States, 85710 United States, California The Neurology Center Encinitas, California, United States, 92024 Northridge Neurological Center Northridge, California, United States, 91325 The Neurology Center Oceanside, California, United States, 92056 Neurology Medical Group of Diablo Valley Walnut Creek, California, United States, 94598 United States, Colorado Colorado Neurology Movement Disorders Center Englewood, Colorado, United States, 80110 United States, Connecticut Yale Center for MS Treatment and Research New Haven, Connecticut, United States, 06510 United States, Florida Neurology Clinic Research Institution Plantation, Florida, United States, 33324 Axiom Clinical Research Tampa, Florida, United States, 33609 United States, Georgia Comprehensive Neurology Specialists, PC Atlanta, Georgia, United States, 30338 Neurotrials Research, Inc. Atlanta, Georgia, United States, 30342 United States, Illinois Springfield Clinic Neuroscience Institute Springfield, Illinois, United States, 62702 United States, Minnesota The Minneapolis Clinic of Neurology, Ltd. Minneapolis, Minnesota, United States, 55422 United States, Oklahoma Neurological Associates of Tulsa, Inc. Tulsa, Oklahoma, United States, 74136-8327 United States, Oregon Medford Neurological and Spine Clinic Medford, Oregon, United States, 97504-8456 United States, Rhode Island Sargent Rehabilitation Center Warwick, Rhode Island, United States, 02818 Collapse << |
NCT01839279 | Spasticity | Phase 2 | Completed | - | United States, Texas ... more >> Covance- Dallas Dallas, Texas, United States, 75247 Collapse << |
NCT00464958 | Spasticity Mu... more >>ltiple Sclerosis Collapse << | Phase 1 Phase 2 | Terminated(Study was stopped a... more >>s the sponsor is no longer funding this project) Collapse << | - | Israel ... more >> Tel Aviv Sourasky Medical Center Tel Aviv, Israel, 64239 Collapse << |
NCT01405950 | Spasticity Due to Cerebral Pal... more >>sy Collapse << | Phase 1 | Terminated(Please see 'Further... more >> study details as provided by Acorda Therapeutics' for explanation of why study stopped.) Collapse << | - | United States, Kentucky ... more >> University of Louisville Department of Neurology dba Kentucky Neuroscience Research Health Care Outpatient Center (HCOC) Louisville, Kentucky, United States, 40202 Collapse << |
NCT01839279 | - | - | Completed | - | - |
NCT02508805 | Vertebrogenic Radiculopathy L5... more >>, S1 Collapse << | Phase 3 | Completed | - | Russian Federation ... more >> State Autonomous Institution Republican Clinical Centre of Neurology Kazan, Republic of Tatarstan, Russian Federation, 420021 Collapse << |
NCT02016443 | Unilateral Inguinal Hernia | Phase 4 | Completed | - | Turkey ... more >> Diskapi Yildirim Beyazit training and research hospital Ankara, Turkey Collapse << |
NCT02725359 | Thyroidectomy | Phase 4 | Completed | - | Turkey ... more >> Ataturk University Yakutiye, Erzurum, Turkey, 25100 Collapse << |
NCT01065987 | Healthy | Phase 1 | Completed | - | Canada ... more >> Anapharm Inc. Sainte-Foy (Quebec), Canada Collapse << |
NCT01405950 | - | - | Terminated(Please see 'Further... more >> study details as provided by Acorda Therapeutics' for explanation of why study stopped.) Collapse << | - | - |
NCT02934061 | Low Back Pain | Phase 3 | Completed | - | Romania ... more >> Opera Contract Research Organization SRL Timisoara, Timis, Romania, 300209 Collapse << |
NCT01146028 | Healthy | Phase 1 | Completed | - | Canada ... more >> Anapharm Inc. Sainte-Foy (Quebec), Canada Collapse << |
NCT02403687 | - | - | Completed | - | - |
NCT01753882 | Spinal Cord Injury | Phase 1 | Unknown | July 2017 | United States, Illinois ... more >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 Collapse << |
NCT01547234 | - | - | Completed | - | Israel ... more >> Multiple Sclerosis Center Carmel Medical Center Haifa, Israel Collapse << |
NCT02907775 | Muscle Spasticity ... more >> Stroke Collapse << | Not Applicable | Recruiting | November 30, 2018 | United Kingdom ... more >> Sheffield Teaching Hospitals NHS FT Recruiting Sheffield, United Kingdom Contact: Alisha Patel alisha.patel@sth.nhs.uk Collapse << |
NCT01068847 | Drug Dependence | Phase 1 | Completed | - | United States, Arkansas ... more >> University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 Collapse << |
NCT02887534 | Acute Muscle Pain | Phase 2 | Withdrawn | December 2017 | - |
NCT03068897 | Low Back Pain | Phase 4 | Completed | - | United States, New York ... more >> Montefiore Medical Center Bronx, New York, United States, 10467 Collapse << |
NCT01788969 | Spinal Cord Injury | Phase 1 | Unknown | December 2017 | United States, Illinois ... more >> Rehabilitation Institute of Chicago Chicago, Illinois, United States, 60611 Collapse << |
NCT02508805 | Vertebrogenic Radiculopathy L5... more >>, S1 Collapse << | Phase 3 | Completed | - | Russian Federation ... more >> State Autonomous Institution Republican Clinical Centre of Neurology Kazan, Republic of Tatarstan, Russian Federation, 420021 Collapse << |
NCT01244113 | Cerebral Palsy | Not Applicable | Completed | - | Korea, Republic of ... more >> Severance Hospital Seoul, Korea, Republic of, 120-752 Collapse << |
NCT00430196 | Upper Limb Spasticity | Phase 4 | Completed | - | - |
NCT00047580 | Multiple Sclerosis ... more >> Muscle Spasticity Spinal Cord Injury Stroke Collapse << | Phase 3 | Completed | - | United States, Arizona ... more >> Radiant Research Tucson, Arizona, United States, 85710 United States, California The Neurology Center Encinitas, California, United States, 92024 Northridge Neurological Center Northridge, California, United States, 91325 The Neurology Center Oceanside, California, United States, 92056 Neurology Medical Group of Diablo Valley Walnut Creek, California, United States, 94598 United States, Colorado Colorado Neurology Movement Disorders Center Englewood, Colorado, United States, 80110 United States, Connecticut Yale Center for MS Treatment and Research New Haven, Connecticut, United States, 06510 United States, Florida Neurology Clinic Research Institution Plantation, Florida, United States, 33324 Axiom Clinical Research Tampa, Florida, United States, 33609 United States, Georgia Comprehensive Neurology Specialists, PC Atlanta, Georgia, United States, 30338 Neurotrials Research, Inc. Atlanta, Georgia, United States, 30342 United States, Illinois Springfield Clinic Neuroscience Institute Springfield, Illinois, United States, 62702 United States, Minnesota The Minneapolis Clinic of Neurology, Ltd. Minneapolis, Minnesota, United States, 55422 United States, Oklahoma Neurological Associates of Tulsa, Inc. Tulsa, Oklahoma, United States, 74136-8327 United States, Oregon Medford Neurological and Spine Clinic Medford, Oregon, United States, 97504-8456 United States, Rhode Island Sargent Rehabilitation Center Warwick, Rhode Island, United States, 02818 Collapse << |
NCT02853240 | Cerebral Palsy | Not Applicable | Recruiting | April 2020 | France ... more >> Hôpital Femme Mère Enfant Recruiting Bron, France, 69500 Contact: Claire MIETTON, MD (0)4 72 12 95 04 ext +33 claire.mietton@chu-lyon.fr Contact: Tiphanie GINHOUX, CRA (0)4 72 35 72 31 ext +33 tiphanie.ginhoux@chu-lyon.fr Collapse << |
NCT01844674 | Malignant Melanoma, Neoplasms | Phase 1 | Completed | - | United States, California ... more >> Diablo Valley Oncology and Hematology Pleasant Hill, California, United States, 94523 United States, Michigan Karmanos Cancer Center Detroit, Michigan, United States, 48201 United States, North Carolina Duke University Health Systems Durham, North Carolina, United States, 27710 Brazil Instituto Nacional do Cancer - INCA Rio de Janeiro, RJ, Brazil, 20560-120 Hospital de Caridade de Ijui; Oncologia Ijui, RS, Brazil, 98700-000 CITO - Centro Integrado de Terapia Onco-Hematológica - Hospital da Cidade de Passo Fundo Passo Fundo, RS, Brazil, 99010-260 Hospital Sao Lucas - PUCRS Porto Alegre, RS, Brazil, 90610-000 Canada, Quebec CSSS champlain - Charles-Le Moyne Greenfield Park, Quebec, Canada, J4V 2H1 Cyprus Bank of Cyprus Oncology Center Nicosia, Cyprus, 2006 Korea, Republic of Severance Hospital, Yonsei University Health System Seoul, Korea, Republic of, 03722 Samsung Medical Center Seoul, Korea, Republic of, 06351 Asan Medical Center. Seoul, Korea, Republic of, 138-736 Collapse << |
NCT02934061 | Low Back Pain | Phase 3 | Completed | - | Romania ... more >> Opera Contract Research Organization SRL Timisoara, Timis, Romania, 300209 Collapse << |
NCT01979510 | Low Back Pain | Phase 3 | Withdrawn | May 2014 | - |
NCT00287157 | Traumatic Brain Injury | Phase 1 | Completed | - | Israel ... more >> Alyn Hospital Pediatric and Adolescent Rehabilitation Center Jerusalem, Israel, 01090 Collapse << |
NCT00464958 | Spasticity Mu... more >>ltiple Sclerosis Collapse << | Phase 1 Phase 2 | Terminated(Study was stopped a... more >>s the sponsor is no longer funding this project) Collapse << | - | Israel ... more >> Tel Aviv Sourasky Medical Center Tel Aviv, Israel, 64239 Collapse << |
NCT00358293 | Muscle Spasticity | Phase 1 Phase 2 | Completed | - | Israel ... more >> Tel Aviv Sourasky Medical Center- Neurology Department Tel Aviv, Israel Collapse << |
NCT01405950 | Spasticity Due to Cerebral Pal... more >>sy Collapse << | Phase 1 | Terminated(Please see 'Further... more >> study details as provided by Acorda Therapeutics' for explanation of why study stopped.) Collapse << | - | United States, Kentucky ... more >> University of Louisville Department of Neurology dba Kentucky Neuroscience Research Health Care Outpatient Center (HCOC) Louisville, Kentucky, United States, 40202 Collapse << |
NCT01839279 | - | - | Completed | - | - |
NCT01146028 | Healthy | Phase 1 | Completed | - | Canada ... more >> Anapharm Inc. Sainte-Foy (Quebec), Canada Collapse << |
NCT02725359 | Thyroidectomy | Phase 4 | Completed | - | Turkey ... more >> Ataturk University Yakutiye, Erzurum, Turkey, 25100 Collapse << |
NCT02016443 | Unilateral Inguinal Hernia | Phase 4 | Completed | - | Turkey ... more >> Diskapi Yildirim Beyazit training and research hospital Ankara, Turkey Collapse << |
NCT01839279 | Spasticity | Phase 2 | Completed | - | United States, Texas ... more >> Covance- Dallas Dallas, Texas, United States, 75247 Collapse << |
NCT01065987 | Healthy | Phase 1 | Completed | - | Canada ... more >> Anapharm Inc. Sainte-Foy (Quebec), Canada Collapse << |
NCT01405950 | - | - | Terminated(Please see 'Further... more >> study details as provided by Acorda Therapeutics' for explanation of why study stopped.) Collapse << | - | - |
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