生物活性

• 描述Trandolapril is an ACE inhibitor used to treat high blood pressure.
• 临床研究

• NCT号	适应症或疾病	临床期	招募状态	预计完成时间	地点
  NCT00391846	Heart Failure ... more >> Ventricular Dysfunction, Left Collapse <<	Phase 4	Completed	-	Sweden ... more >> Research Site Alvesta, Sweden Research Site Arvika, Sweden Research Site Bjuv, Sweden Research Site Borensberg, Sweden Research Site Bromma, Sweden Research Site Dalby, Sweden Research Site Eskilstuna, Sweden Research Site Gagnef, Sweden Research Site Goeteborg, Sweden Research Site Hisings Karra, Sweden Research Site Huddinge, Sweden Research Site Huskvarna, Sweden Research Site Joenkoeping, Sweden Research Site Kalmar, Sweden Research Site Kungalv, Sweden Research Site Lerum, Sweden Research Site Lessebo, Sweden Research Site Lidkoping, Sweden Research Site Lilla Edet, Sweden Research Site Linkoeping, Sweden Research Site Ludvika, Sweden Research Site Lyckeby, Sweden Research Site Malmo, Sweden Research Site Moheda, Sweden Research Site Motala, Sweden Research Site Orebro, Sweden Research Site Ostersund, Sweden Research Site Skanor, Sweden Research Site Soderakra, Sweden Research Site Stenungsund, Sweden Research Site Stocksund, Sweden Research Site Timra, Sweden Research Site Uddevalla, Sweden Research Site Ulricehamn, Sweden Research Site Umea, Sweden Research Site Uppsala, Sweden Research Site Vasteras, Sweden Research Site Vastervik, Sweden Research Site Vaxjo, Sweden Collapse <<
  NCT01715584	Hypertension	Phase 4	Recruiting	December 31, 2019	Canada, Ontario ... more >> London Health Sciences Centre - Victoria Campus Recruiting London, Ontario, Canada, N6A 5W9 Contact: Craig J Railton, MD, PhD    519 685 8500 ext 58525    Craig.Railton@lhsc.on.ca    Principal Investigator: Craig J Railton, MD, PhD          Sub-Investigator: Jonathan Fairbairn, BSc          Sub-Investigator: George Nicoloau, MD          Sub-Investigator: Robert Gros, PhD          Sub-Investigator: Jason Franklin, MD          Sub-Investigator: John Yoo, MD          Sub-Investigator: Kevin Fung, MD          Sub-Investigator: Anthony Nichols, MD          Sub-Investigator: Danielle McNeil, MD Collapse <<
  NCT01669434	Hypotension on Induction	Phase 4	Completed	-	United States, Nebraska ... more >> University of Nebraska Medical Center Omaha, Nebraska, United States, 68198 Collapse <<

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• 参考文献

• [1] Tan X, He W, Liu Y. Combination therapy with paricalcitol and trandolapril reduces renal fibrosis in obstructive nephropathy. Kidney Int. 2009 Dec;76(12):1248-57.

  [2] Zhu HJ, Langaee TY, et al. CES1P1 variant -816A>C is not associated with hepatic carboxylesterase 1 expression and activity or antihypertensive effect of trandolapril. Eur J Clin Pharmacol. 2016 Jun;72(6):681-7.