CAS No.: 1496551-77-9
Uprifosbuvir Catalog No. CSN19730
Synonyms: IDX21437;MK-3682
Uprifosbuvir is an uridine nucleotide analog HCV NS5B polymerase inhibitor.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02661126 Hepatitis C Phase 1 Completed - - NCT02613403 Hepatitis Hep... more >>atitis C Digestive System Diseases Flaviviridae Infections Hepatitis, Viral, Human Liver Diseases RNA Virus Infections Virus Diseases Collapse << Phase 2 Terminated - - NCT02613403 - - Terminated - - - 更多
- 参考文献
- [1] Ramirez S, Mikkelsen LS, et al. Robust HCV Genotype 3a Infectious Cell Culture System Permits Identification of Escape Variants With Resistance to Sofosbuvir. Gastroenterology. 2016 Nov;151(5):973-985.e2.
- [2] Lagrutta A, Regan CP, et al. Cardiac drug-drug interaction between HCV-NS5B pronucleotide inhibitors and amiodarone is determined by their specific diastereochemistry. Sci Rep. 2017 Mar 22;7:44820.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 1496551-77-9 | 储存条件 |
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| 分子式 | C22H29ClN3O9P | 运输 | 蓝冰 | |
| 分子量 | 545.91 | 别名 | IDX21437;MK-3682 |
