CAS No.: 137234-62-9
Voriconazole/伏立康唑 Catalog No. CSN12213
Synonyms: UK-109496;DRG 0301;VRC
Voriconazole is a second-generation triazole antifungal used to treat serious fungal infections by inhibiting the synthesis of ergosterol, the major sterol of the fungal cell membrane.
400-920-2911
sales@csnpharm.cn
tech@csnpharm.cn
纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02381080 B-Cell Chronic Lymphocytic Leu... more >>kemia Collapse << Phase 1 Completed - Canada ... more >> N/a N/a, Canada Russian Federation Moscow, Russian Federation Petrozavodsk, Russian Federation St. Petersburg, Russian Federation Spain Madrid, Spain Pamplona, Spain Collapse << NCT00003031 Infection Pul... more >>monary Complications Collapse << Phase 3 Completed - - NCT01787032 Healthy Phase 1 Completed - Germany ... more >> Boehringer Ingelheim Investigational Site Ingelheim, Germany Collapse << - 更多
- 参考文献
- [1] Diekema DJ, Messer SA, et al. Activities of caspofungin, itraconazole, posaconazole, ravuconazole, voriconazole, and amphotericin B against 448 recent clinical isolates of filamentous fungi. J Clin Microbiol. 2003 Aug;41(8):3623-6.
- [2] Espinel-Ingroff A. In vitro activity of the new triazole voriconazole(UK-109,496) against opportunistic filamentous and dimorphic fungi and common and emerging yeast pathogens. J Clin Microbiol. 1998 Jan;36(1):198-202.
- [3] Vlada B Urlacher,et al. Cytochrome P450 Monooxygenases in Biotechnology and Synthetic Biology. Trends Biotechnol.2019 Aug;37(8):882-897.
- [4] Mikus G, Scholz IM, Weiss J. Pharmacogenomics of the triazole antifungal agent voriconazole. Pharmacogenomics. 2011 Jun;12(6):861-72. doi: 10.2217/pgs.11.18.
- [5] Scholz I, Oberwittler H, Riedel KD, et al. Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype. Br J Clin Pharmacol. 2009 Dec;68(6):906-15. doi: 10.1111/j.1365-2125.2009.03534.x.
- [6] Raoul Herbrecht. Voriconazole: therapeutic review of a new azole antifungal. Expert Rev Anti Infect Ther. 2004 Aug;2(4):485-97.
- [7] Jiquan Shen,et al. Effects of Voriconazole on the Pharmacokinetics of Vonoprazan in Rats. Drug Des Devel Ther. 2020 Jun 4;14:2199-2206.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 137234-62-9 | 储存条件 |
|
|||||||||||
| 分子式 | C16H14F3N5O | 运输 | 蓝冰 | |||||||||||
| 分子量 | 349.31 | 别名 | UK-109496;DRG 0301;VRC;UK-109,496;Vfend;伏立康唑 | |||||||||||
| 溶解度 |
|
动物实验配方 |
|
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT02381080 | B-Cell Chronic Lymphocytic Leu... more >>kemia Collapse << | Phase 1 | Completed | - | Canada ... more >> N/a N/a, Canada Russian Federation Moscow, Russian Federation Petrozavodsk, Russian Federation St. Petersburg, Russian Federation Spain Madrid, Spain Pamplona, Spain Collapse << |
| NCT00003031 | Infection Pul... more >>monary Complications Collapse << | Phase 3 | Completed | - | - |
| NCT01787032 | Healthy | Phase 1 | Completed | - | Germany ... more >> Boehringer Ingelheim Investigational Site Ingelheim, Germany Collapse << |
| NCT00177788 | - | - | Completed | - | United States, Pennsylvania ... more >> University of Pittsburgh Medical Center Pittsburgh, Pennsylvania, United States, 15213 Collapse << |
| NCT00624143 | Pediatric Acute Leukemia Induc... more >>tion Collapse << | Phase 3 | Unknown | - | India ... more >> Institute Rotary Cancer Hospital, All India Institute of Medical Sciences Recruiting New Delhi, Delhi, India, 110029 Contact: SAMEER BAKHSHI, MD 91-11-26588153 sambakh@hotmail.com Collapse << |
| NCT01787032 | - | - | Completed | - | - |
| NCT00001646 | Acquired Immunodeficiency Synd... more >>rome Aspergillosis HIV Infections Immunologic Deficiency Syndromes Neutropenia Collapse << | Phase 3 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT03554239 | Infection | Not Applicable | Terminated | - | - |
| NCT00079222 | Cancer | Not Applicable | Completed | - | United States, California ... more >> Jonsson Comprehensive Cancer Center, UCLA Los Angeles, California, United States, 90095-1678 Collapse << |
| NCT01321372 | - | - | Completed | - | Canada, Ontario ... more >> Princess Margaret Hospital Toronto, Ontario, Canada, M5G 2M9 Collapse << |
| NCT00059878 | Infection Uns... more >>pecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Completed | - | United States, Arkansas ... more >> Arkansas Cancer Research Center at University of Arkansas for Medical Sciences Little Rock, Arkansas, United States, 72205 United States, Florida Shands Cancer Center at the University of Florida Health Science Center Gainesville, Florida, United States, 32610-100277 United States, Maryland Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support Bethesda, Maryland, United States, 20892-1182 Collapse << |
| NCT00740389 | HIV AIDS ... more >> Fungal Infection Collapse << | Phase 1 | Completed | - | - |
| NCT00001757 | Mycoses | Phase 3 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00557362 | Fungal Keratitis | Phase 1 Phase 2 | Completed | - | India ... more >> Aravind Eye Hospital Madurai, Tamil Nadu, India Aravind Eye Hospital Pondicherry, Tamil Nadu, India Collapse << |
| NCT00015665 | Mycoses | Phase 3 | Completed | - | United States, Maryland ... more >> National Institute of Allergy and Infectious Diseases (NIAID) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00557362 | - | - | Completed | - | - |
| NCT00001810 | Aspergillosis ... more >> Candidiasis Fungemia Mycoses Collapse << | Phase 3 | Completed | - | United States, Maryland ... more >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00005912 | Aspergillosis ... more >> Candidiasis Fungal Diseases Mycoses Collapse << | Phase 1 | Completed | - | United States, Maryland ... more >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT01344512 | Pediatrics Ce... more >>ftazidime Ciprofloxacin Voriconazole Collapse << | Not Applicable | Completed | - | France ... more >> CHU de Bordeaux, Hôpital Pellegrin Bordeaux, France, 33076 Hospices Civils de Lyon Bron, France, 69500 CHU Clermont Ferrand Clermont Ferrand, France, 63000 CHU de Dijon Dijon, France, 21079 CHU de Grenoble Grenoble, France, 38043 CHRU Lille Lille, France, 59037 AP-HM, Hôpital La Timone Marseille, France, 13005 CHU Montpellier Montpellier, France, 34925 APHP - Hôpital NEcker Paris, France, 75015 AP-HP - Hôpital Robert Debré Paris, France, 75019 CHU Poitiers Poitiers, France, 86000 CHU Rouen Rouen, France, 76031 CHU Toulouse Toulouse, France, 31059 CHU tours Tours, France, 37044 Collapse << |
| NCT00288197 | Invasive Fungal Infections | Phase 4 | Completed | - | China, Guangdong ... more >> Pfizer Investigational Site Guangzhou, Guangdong, China, 510080 China, Hubei Pfizer Investigational Site Wuhan, Hubei, China, 430022 Pfizer Investigational Site Wuhan, Hubei, China, 430030 China Pfizer Investigational Site Beijing, China, 100083 Pfizer Investigational Site Beijing, China, 100853 Pfizer Investigational Site Hangzhou, China, 310003 Pfizer Investigational Site Shanghai, China, 200040 Pfizer Investigational Site Shanghai, China, 200080 Pfizer Investigational Site Tianjin, China, 300020 Pfizer Investigational Site Tianjin, China, 300052 Collapse << |
| NCT00066599 | Kidney Cancer ... more >> Leukemia Lymphoma Multiple Myeloma and Plasma Cell Neoplasm Myelodysplastic Syndromes Myelodysplastic/Myeloproliferative Neoplasms Neuroblastoma Neutropenia Sarcoma Collapse << | Phase 2 | Completed | - | United States, California ... more >> Children's Hospital of Orange County Orange, California, United States, 92868 Children's Hospital and Health Center, San Diego San Diego, California, United States, 92123-4282 United States, Maryland Warren Grant Magnuson Clinical Center - NCI Clinical Studies Support Bethesda, Maryland, United States, 20892-1182 United States, North Carolina Duke Comprehensive Cancer Center Durham, North Carolina, United States, 27710 United States, Ohio Ireland Cancer Center Cleveland, Ohio, United States, 44106-5065 United States, Pennsylvania Children's Hospital of Philadelphia Philadelphia, Pennsylvania, United States, 19104-4318 United States, Texas Simmons Cancer Center at University of Texas Southwestern Medical Center - Dallas Dallas, Texas, United States, 75390 Collapse << |
| NCT00412893 | Aspergillosis ... more >> Invasive Fungal Infection Collapse << | Phase 3 | Completed | - | - |
| NCT02180165 | Aspergillosis | Phase 3 | Completed | - | - |
| NCT01621321 | Allergic Bronchopulmonary Aspe... more >>rgillosis Collapse << | Phase 2 Phase 3 | Completed | - | India ... more >> Postgraduate Institute of Medical Education and Research Chandigarh, India, 160012 Collapse << |
| NCT00001940 | Mycoses | Phase 3 | Completed | - | United States, Maryland ... more >> National Cancer Institute (NCI) Bethesda, Maryland, United States, 20892 Collapse << |
| NCT00418951 | Acute Myelogenous Leukemia ... more >> Myelodysplastic Syndrome Collapse << | Phase 2 | Completed | - | United States, Texas ... more >> The University of Texas M D Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT00423163 | Aspergillosis/Blood ... more >> Aspergillosis/Invasive Collapse << | Phase 4 | Withdrawn(An alternative joint... more >> industry effort will provide information on combination versus single agent therapy for treatment of aspergillosis) Collapse << | - | - |
| NCT00412893 | - | - | Completed | - | - |
| NCT00150319 | Kidney Failure | Phase 1 Phase 2 | Terminated(See Detailed Descri... more >>ption) Collapse << | - | United States, Louisiana ... more >> Pfizer Investigational Site New Orleans, Louisiana, United States, 70118 Pfizer Investigational Site New Orleans, Louisiana, United States, 70119 United States, Minnesota Pfizer Investigational Site Minneapolis, Minnesota, United States, 55404 United States, Tennessee Pfizer Investigational Site Knoxville, Tennessee, United States, 37920 United States, Texas Pfizer Investigational Site Austin, Texas, United States, 78727 Pfizer Investigational Site Austin, Texas, United States, 78758 Collapse << |
| NCT00455364 | Infection | Phase 4 | Terminated(Protocol never rece... more >>ived funding.) Collapse << | - | United States, Illinois ... more >> The University of Chicago Chicago, Illinois, United States, 60637 Collapse << |
| NCT00418951 | - | - | Completed | - | - |
| NCT01576315 | Cystic Fibrosis ... more >> Aspergillus Infections Collapse << | Phase 2 | Completed | - | France ... more >> CRCM Adulte et Pédiatrie - Hôpital Nord Amiens, France, 80054 CRCM adulte - Centre Robert Debré Angers, France, 49033 Pediatry - Centre Robert Debré Angers, France, 49033 Pediatric penumologic - Groupe hospitalier de Pellegrin Bordeaux, France, 33000 Pneumology pediatric - Hôpital Femme-Mère-Enfants Bron, France, 69500 CRCM - Pediatry - CHI Créteil Créteil, France, 94000 Service de Pneumologie-Immuno-Allergologie / Hôpital Calmette Lille, France, 59037 Hôpital Nord - Pneumology Marseille, France, 13015 Pneumologie Infantile - Hôpital des enfants Nancy, France, 54577 CRCM - Hôpital Sud Rennes, France, 35000 Pneumology - Hôpital Pontchaillou Rennes, France, 35000 CRCM Pédiatrique - Hôpital de Hautepierre Strasbourg, France, 67098 Pédiatrie - Pneumologie, Allergologie - Hôpital des enfants Toulouse, France, 31059 Pneumology - CH Bretagne-Atlantique Vannes, France, 56017 United Kingdom Manchester Adult Cystic Fibrosis Centre - University Hospital of South Manchester Manchester, United Kingdom, M23 9LT Collapse << |
| NCT00940017 | Aspergillosis ... more >> Candidemia Collapse << | Phase 4 | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site Hartford, Connecticut, United States, 06102 Collapse << |
| NCT00673348 | - | - | Unknown | April 2010 | Korea, Republic of ... more >> St. Mary's Hospital Not yet recruiting Seoul, Korea, Republic of, 150-713 Contact: Dong-Gun Lee, M.D., Ph.D. 82-2-3779-1114 ext 1099 symonlee@catholic.ac.kr Principal Investigator: Dong-Gun Lee, M.D., Ph.D. St. Mary's Hospital Recruiting Seoul, Korea, Republic of, 150-713 Contact: Hae-Young Youn, Pharm D 82-2-3779-1114 ext 1216 baram@catholic.ac.kr Collapse << |
| NCT00940017 | - | - | Completed | - | - |
| NCT01207128 | Aspergillosis | Phase 2 | Withdrawn(None enrolled) | - | United States, Arkansas ... more >> UAMS Little Rock, Arkansas, United States, 72205 University of Arkansas Little Rock, Arkansas, United States, 72205 Collapse << |
| NCT00647907 | Candidiasis C... more >>ryptococcosis Aspergillosis Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Pfizer Investigational Site Kaohsiung, Taiwan Pfizer Investigational Site Taichung, Taiwan, 40705 Pfizer Investigational Site Taipei, Taiwan, 100 Pfizer Investigational Site Taipei, Taiwan, 114 Collapse << |
| NCT00548262 | Candidemia In... more >>vasive Candidiasis Collapse << | Phase 4 | Completed | - | Brazil ... more >> Pfizer Investigational Site Brasilia, DF, Brazil, 70710-905 Pfizer Investigational Site Curitiba, PR, Brazil, 80060-900 Pfizer Investigational Site Rio de Janeiro, RJ, Brazil, 21941-913 Pfizer Investigational Site Porto Alegre, RS, Brazil, 90020-090 Pfizer Investigational Site Porto Alegre, RS, Brazil, 90110-270 Pfizer Investigational Site Sao Jose do Rio Preto, SP, Brazil, 15090-000 Chile Pfizer Investigational Site Independencia, Santiago, RM, Chile, 8380456 Colombia Pfizer Investigational Site Bogota DC, Cundinamarca, Colombia, 0000 Pfizer Investigational Site Cali, Valle Del Cauca, Colombia, 0000 Mexico Pfizer Investigational Site Leon, Guanajuato, Mexico, 37320 Pfizer Investigational Site Guadalajara, Jalisco, Mexico, 44280 Pfizer Investigational Site San Luis Potosi, Mexico, 78240 Panama Pfizer Investigational Site Panama, Panama Collapse << |
| NCT03230058 | Infection, Fungal | Phase 2 Phase 3 | Recruiting | September 30, 2018 | India ... more >> GMRV Campus LV Prasad Eye Insitute Recruiting Visakhapatnam, Andhra Pradesh, India Contact: Merle Fernandes, MS merle@lvpei.org Contact: Antonio Di Zazzo, MD antoniodizazzo@gmail.com Collapse << |
| NCT00833482 | Human Immunodeficiency Virus T... more >>ype 1 (HIV-1) HIV Infections Collapse << | Phase 1 | Completed | - | United States, California ... more >> West Coast Clinical Trials, Llc Cypress, California, United States, 90630 Netherlands Local Institution Nijmegen, Netherlands, 6425 GA Collapse << |
| NCT00289991 | Antifungal Prophylaxis of Inva... more >>sive Fungal Infections Collapse << | Phase 3 | Completed | - | - |
| NCT00159822 | Aspergillosis | Phase 2 Phase 3 | Completed | - | France ... more >> Pfizer Investigational Site Nantes, Cedex, France, 44093 Pfizer Investigational Site Angers Cedex, France, 49033 Pfizer Investigational Site Bobigny, France, 93000 Pfizer Investigational Site Brest Cedex, France, 29609 Pfizer Investigational Site Bris Sous Forges, France, 94640 Pfizer Investigational Site Caen Cedex, France, 14033 Pfizer Investigational Site Dinan Cedex, France, 22101 Pfizer Investigational Site Grenoble Cedex 09, France, 38043 Pfizer Investigational Site Lille Cedex, France, 59037 Pfizer Investigational Site Lyon Cedex, France, 69394 Pfizer Investigational Site Montpellier Cedex 5, France, 34295 Pfizer Investigational Site Paris Cedex 18, France, 75877 Pfizer Investigational Site Paris Cedex 20, France, 75970 Pfizer Investigational Site Paris, France, 75010 Pfizer Investigational Site Poitiers Cedex, France, 86021 Pfizer Investigational Site Reims Cedex, France, 51092 Pfizer Investigational Site Rouen Cedex, France, 76031 Pfizer Investigational Site Suresnes, France, 92150 Collapse << |
| NCT00159822 | - | - | Completed | - | - |
| NCT00143312 | Prophylaxis Of Invasive Fungal... more >> Infections Collapse << | Phase 4 | Completed | - | Belgium ... more >> Pfizer Investigational Site Leuven, Belgium, 3000 France Pfizer Investigational Site Marseille, Cedex 09, France, 13273 Pfizer Investigational Site Creteil, France, 94010 Pfizer Investigational Site Nantes, France, 44035 cedex Pfizer Investigational Site Pessac, France, 33600 Pfizer Investigational Site Strasbourg, France, 67098 Germany Pfizer Investigational Site Koeln, Germany, 50937 Pfizer Investigational Site Mainz, Germany, 55101 Pfizer Investigational Site Wuerzburg, Germany, 97070 Portugal Pfizer Investigational Site Lisboa, Portugal, 1099-023 Spain Pfizer Investigational Site Barcelona, Spain, 08025 Pfizer Investigational Site Barcelona, Spain, 08036 Pfizer Investigational Site Madrid, Spain, 28006 Sweden Pfizer Investigational Site Stockholm, Sweden, 141 86 Switzerland Pfizer Investigational Site CH-4031 Basel, Switzerland United Kingdom Pfizer Investigational Site London, United Kingdom, W12 0NN Pfizer Investigational Site Manchester, United Kingdom, M20 4BX Collapse << |
| NCT00548262 | - | - | Completed | - | - |
| NCT00289991 | - | - | Completed | - | - |
| NCT00136968 | Fungal Infection | Phase 1 | Completed | - | - |
| NCT03515382 | Healthy | Phase 1 | Completed | - | United Kingdom ... more >> Quotient Sciences Limited Ruddington, United Kingdom Collapse << |
| NCT00833482 | - | - | Completed | - | - |
| NCT00143312 | - | - | Completed | - | - |
| NCT00150345 | Possible Fungal Infection | Phase 3 | Completed | - | Germany ... more >> Pfizer Investigational Site Augsburg, Germany, 86156 Pfizer Investigational Site Berlin, Germany, 10117 Pfizer Investigational Site Berlin, Germany, 12200 Pfizer Investigational Site Berlin, Germany, 13353 Pfizer Investigational Site Bielefeld, Germany, 33611 Pfizer Investigational Site Bremen, Germany, 28177 Pfizer Investigational Site Chemnitz, Germany, 09113 Pfizer Investigational Site Dresden, Germany, 01307 Pfizer Investigational Site Erlangen, Germany, 91054 Pfizer Investigational Site Essen, Germany, 45239 Pfizer Investigational Site Frankfurt (Oder), Germany, 15236 Pfizer Investigational Site Freiburg, Germany, 79106 Pfizer Investigational Site Goettingen, Germany, 37075 Pfizer Investigational Site Hannover, Germany, 30623 Pfizer Investigational Site Homburg/Saar, Germany, 66421 Pfizer Investigational Site Kiel, Germany, 24116 Pfizer Investigational Site Koeln, Germany, 50937 Pfizer Investigational Site Leipzig, Germany, 04103 Pfizer Investigational Site Ludwigshafen, Germany, 67063 Pfizer Investigational Site Luebeck, Germany, 23538 Pfizer Investigational Site Mainz, Germany, 55101 Pfizer Investigational Site Muenchen, Germany, 81675 Pfizer Investigational Site Muenchen, Germany, 81737 Pfizer Investigational Site Potsdam, Germany, 14467 Pfizer Investigational Site Stuttgart, Germany, 70376 Pfizer Investigational Site Trier, Germany, 54290 Pfizer Investigational Site Wiesbaden, Germany, 65191 Pfizer Investigational Site Wuerzburg, Germany, 97070 Collapse << |
| NCT01418846 | - | - | Completed | - | Belgium ... more >> Ghent University Hospital - Cystic Fibrosis Clinic Ghent, East Flanders, Belgium, 9000 University Hospitals Leuven Leuven, Vlaams-Brabant, Belgium, 3000 University Hospital Brussels - Cystic Fibrosis Clinic Brussels, Belgium, 1090 Collapse << |
| NCT00238355 | - | - | Terminated(competing study at ... more >>site) Collapse << | - | - |
| NCT00150345 | - | - | Completed | - | - |
| NCT01657201 | Systemic Mycotic Infection | Phase 1 | Completed | - | Korea, Republic of ... more >> Clinical Research Institute, Seoul National University Hospital Seoul, Korea, Republic of Collapse << |
| NCT00942773 | Healthy | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul National University Hospital Clinical Trial Center Seoul, Korea, Republic of, 110-744 Collapse << |
| NCT02074462 | - | - | Completed | - | Netherlands ... more >> University Medical Center Groningen Groningen, Netherlands, 9700 RB Collapse << |
| NCT00174473 | Neutropenia | Phase 1 Phase 2 | Completed | - | - |
| NCT00745992 | - | - | Unknown | July 2011 | Taiwan ... more >> National Taiwan University Hospital Not yet recruiting Taipei, Taiwan, 100 Contact: Shu-Wen Lin, PharmD, MS 886-2-2312-3456 ext 88408 shuwenlin@ntu.edu.tw Contact: Fe-Lin L. Wu, Ph.D. 886-2-2312-3456 ext 88389 flwu@ntu.edu.tw Principal Investigator: Shu-Wen Lin, PharmD, MS Sub-Investigator: Fe-Lin L. Wu, Ph.D. Collapse << |
| NCT00075803 | Lymphoma Infe... more >>ction Leukemia Collapse << | Phase 3 | Completed | - | - |
| NCT00620074 | - | - | Terminated(See Detailed Descri... more >>ption) Collapse << | - | - |
| NCT00075803 | - | - | Completed | - | - |
| NCT00997035 | - | - | Completed | - | - |
| NCT00997035 | Corneal Ulcer ... more >> Eye Infections, Fungal Collapse << | Phase 3 | Completed | - | United States, California ... more >> Proctor Foundation, UCSF San Francisco, California, United States, 94143 India Aravind Eye Hospital Coimbatore, Tamil Nadu, India Aravind Eye Hospitals Madurai, Tamil Nadu, India Aravind Eye Hospital Pondicherry, Tamil Nadu, India Aravind Eye Hospital Tirunelveli, Tamil Nadu, India Nepal Bharatpur Eye Hospital Bharatpur, Chitwan, Nepal Lumbini Eye Institute Bhairahawa, Lumbini, Nepal Collapse << |
| NCT01418833 | - | - | Completed | - | Belgium ... more >> University Hospitals Leuven Leuven, Vlaams-Brabant, Belgium, 3000 Collapse << |
| NCT00620074 | Aspergillosis | Phase 4 | Terminated(See Detailed Descri... more >>ption) Collapse << | - | United States, Georgia ... more >> Pfizer Investigational Site Atlanta, Georgia, United States, 30322 United States, Michigan Pfizer Investigational Site Detroit, Michigan, United States, 48202 United States, Texas Pfizer Investigational Site Fort Worth, Texas, United States, 76104 Pfizer Investigational Site Fort Worth, Texas, United States, 76107 Collapse << |
| NCT01104376 | Efavirenz, Metabolism and Phar... more >>macokinetics Changes Collapse << | Not Applicable | Completed | - | United States, Indiana ... more >> Indiana University Indianapolis, Indiana, United States, 46202 Collapse << |
| NCT00836875 | - | - | Terminated(This protocol termi... more >>nated prematurely on July 8, 2013 due to slow enrollment, not because of any safety issues or concerns.) Collapse << | - | - |
| NCT00238355 | Infection Uns... more >>pecified Adult Solid Tumor, Protocol Specific Collapse << | Phase 2 | Terminated(competing study at ... more >>site) Collapse << | - | United States, Oregon ... more >> OHSU Knight Cancer Institute Portland, Oregon, United States, 97239-3098 Collapse << |
| NCT02631954 | Aspergillus Infections ... more >> Candida Infections Fungal Infections Collapse << | Phase 1 | Completed | - | Korea, Republic of ... more >> Inha University Hospital Jung-gu, Incheon, Korea, Republic of, 22332 Collapse << |
| NCT02912156 | Fungus Infection | Phase 4 | Completed | - | - |
| NCT01080651 | Invasive Aspergillosis | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul National University Hospital Clinical Trial Center Seoul, Korea, Republic of Collapse << |
| NCT00836875 | Invasive Aspergillosis | Phase 3 | Terminated(This protocol termi... more >>nated prematurely on July 8, 2013 due to slow enrollment, not because of any safety issues or concerns.) Collapse << | - | United States, California ... more >> Childrens Hospital Los Angeles Los Angeles, California, United States, 90027 Children's Hospital & Research Center Oakland (CHRCO) Oakland, California, United States, 94609 United States, Pennsylvania Children's Hospital of Pittsburgh of UPMC Pittsburgh, Pennsylvania, United States, 15224 United States, Texas The University of Texas MD Anderson Cancer Center Houston, Texas, United States, 77030 United States, Virginia Children's Pavilion, Virginia Commonwealth University Health System Richmond, Virginia, United States, 23219 Virginia Commonwealth University Health System, Hospital Pharmacy Richmond, Virginia, United States, 23298-0042 Pediatric Hematology and Oncology, Virginia Commonwealth University Health System Richmond, Virginia, United States, 23298 Virginia Commonwealth University/MCV Clinical Pathology Richmond, Virginia, United States, 23298 Virginia Commonwealth University Richmond, Virginia, United States, 23298 Canada, Alberta Alberta Children's Hospital, Pediatric Oncology Office Calgary, Alberta, Canada, T3B 6A8 Alberta Children's Hospital Calgary, Alberta, Canada, T3B 6A8 Czechia Fakultni nemocnice Brno Brno, Czechia, 625 00 Fakultni nemocnice Brno Brno, Czechia, 62500 Netherlands UMC St. Radboud Nijmegen, Netherlands, 6500 HB Poland Klinika Transplantacji Szpiku, Onkologii i Hematologii Dzieciecej Wroclaw, Poland, 50-345 Singapore National University Hospital Singapore, Singapore, 119074 KK Women's and Children's Hospital Singapore, Singapore, 229899 Spain Hospital General Universitari Vall D'Hebron Barcelona, Spain, 08035 Hospital Universitari Vall d'Hebron. Servicio de Farmacia Barcelona, Spain, 08035 Hospital Universitario Vall d'Hebron Barcelona, Spain, 08035 HOSPITAL UNIVERSITARIO 12 DE OCTUBRE Servicio de Farmacia Madrid, Spain, 28041 Hospital Universitario 12 de Octubre Madrid, Spain, 28041 Thailand Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University Bangkok noi, Bangkok, Thailand, 10700 Department of Pediatrics, Faculty of Medicine, Chulalongkorn University Patumwan, Bangkok, Thailand, 10330 Department of Pediatrics, Phramongkutklao hospital Rajathevee, Bangkok, Thailand, 10400 Collapse << |
| NCT01073618 | - | - | Completed | - | - |
| NCT00904995 | Leukemia Fung... more >>al Infection Collapse << | Phase 3 | Completed | - | United States, Texas ... more >> UT MD Anderson Cancer Center Houston, Texas, United States, 77030 Collapse << |
| NCT01104376 | - | - | Completed | - | - |
| NCT00904995 | - | - | Completed | - | - |
| NCT00152594 | Leukemia, Myelocytic, Acute | Phase 3 | Terminated | - | Germany ... more >> Johann Wolfgang Goethe-Universität Frankfurt am Main Frankfurt am Main, Germany, 60590 Universitätsklinikum Mannheim, Universität Heidelberg Heidelberg, Germany, 68305 Klinikum der Universität Köln Köln, Germany, 50931 Collapse << |
| NCT00739934 | Candidiasis C... more >>andidemia Collapse << | Phase 2 | Completed | - | United States, Arizona ... more >> Pfizer Investigational Site Tucson, Arizona, United States, 85719 Pfizer Investigational Site Tucson, Arizona, United States, 85724 United States, California Pfizer Investigational Site Orange, California, United States, 92868 United States, Florida Pfizer Investigational Site Jacksonville, Florida, United States, 32207 United States, Georgia Pfizer Investigational Site Atlanta, Georgia, United States, 30322-1062 Pfizer Investigational Site Atlanta, Georgia, United States, 30322 Pfizer Investigational Site Atlanta, Georgia, United States, 30342-1600 United States, Louisiana Pfizer Investigational Site New Orleans, Louisiana, United States, 70118 United States, Maryland Pfizer Investigational Site Baltimore, Maryland, United States, 21215 United States, North Carolina Pfizer Investigational Site Durham, North Carolina, United States, 27710 United States, Ohio Pfizer Investigational Site Cleveland, Ohio, United States, 44106 United States, Oregon Pfizer Investigational Site Portland, Oregon, United States, 97239 United States, Tennessee Pfizer Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas Pfizer Investigational Site Houston, Texas, United States, 77030 Collapse << |
| NCT01073631 | - | - | Completed | - | - |
| NCT01073618 | - | - | Completed | - | - |
| NCT00531479 | - | - | Completed | - | - |
| NCT01782131 | Fungal Infections | Phase 3 | Recruiting | September 16, 2019 | - |
| NCT00531479 | Aspergillosis | Phase 3 | Completed | - | - |
| NCT01073631 | - | - | Completed | - | - |
| NCT00890708 | Mycoses | Not Applicable | Completed | - | Korea, Republic of ... more >> Seoul National University Hospital Seoul, Korea, Republic of, 110-744 Collapse << |
| NCT02906176 | Healthy Volunteers | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul National University Hospital Clinical Trial Center Seoul, Korea, Republic of Collapse << |
| NCT01416025 | - | - | Completed | - | - |
| NCT01148160 | - | - | Terminated | - | Korea, Republic of ... more >> Asan Medical Center, University of Ulsan College of Medicine Seoul, Korea, Republic of, 138-736 Collapse << |
| NCT01383993 | - | - | Completed | - | - |
| NCT01137292 | - | - | Completed | - | - |
| NCT00739934 | - | - | Completed | - | - |
| NCT01137292 | - | - | Completed | - | - |
| NCT00556998 | Pharmacokinetics | Phase 2 | Completed | - | United States, Illinois ... more >> Pfizer Investigational Site Chicago, Illinois, United States, 60637 United States, Louisiana Pfizer Investigational Site New Orleans, Louisiana, United States, 70118 United States, North Carolina Pfizer Investigational Site Durham, North Carolina, United States, 27705 United States, Ohio Pfizer Investigational Site Cleveland, Ohio, United States, 44106 United States, Oregon Pfizer Investigational Site Portland, Oregon, United States, 97239 United States, Tennessee Pfizer Investigational Site Nashville, Tennessee, United States, 37232-2195 Pfizer Investigational Site Nashville, Tennessee, United States, 37232 United States, Texas Pfizer Investigational Site Fort Worth, Texas, United States, 76104-2796 Pfizer Investigational Site Houston, Texas, United States, 77030 Collapse << |
| NCT00556998 | - | - | Completed | - | - |
| NCT03672292 | Invasive Pulmonary Aspergillos... more >>is Collapse << | Phase 2 | Not yet recruiting | October 2020 | - |
| NCT01416025 | Fungal Infection | Phase 4 | Completed | - | United States, Maryland ... more >> Johns Hopkins Baltimore, Maryland, United States, 21205 Collapse << |
| NCT01812473 | - | - | Completed | - | Belgium ... more >> University Hospitals Leuven Leuven, Vlaams-Brabant, Belgium, 3000 Collapse << |
| NCT01812473 | - | - | Completed | - | - |
| NCT02227797 | Fungal Infection | Phase 1 | Active, not recruiting | March 1, 2019 | United States, Minnesota ... more >> University of Minnesota Medical Center, Fairview Minneapolis, Minnesota, United States, 55455 Collapse << |
| NCT01092832 | - | - | Terminated(This protocol termi... more >>nated prematurely on July 8, 2013 due to slow enrollment, not because of any safety issues or concerns.) Collapse << | - | - |
| NCT01480219 | - | - | Completed | - | - |
| NCT01383993 | Aspergillosis, Aspergilloma | Phase 2 | Completed | - | Japan ... more >> Japanese Red Cross Nagoya Daiichi Hospital Nagoya, Aichi, Japan National hospital Organization Nagoya Medical Center Nagoya, Aichi, Japan Sapporo Hokuyu Hosipital Sapporo, Hokkaido, Japan Kanagawa Children's Medical Center Yokohama, Kanagawa, Japan Osaka Medical Center and Research Institute for Maternal and Child Health Izumi, Osaka, Japan Dokkyo Medical University Hospital Shimotsuga-gun, Tochigi, Japan Collapse << |
| NCT01188759 | Aspergillosis ... more >> Invasive Pulmonary Aspergillosis Neuroaspergillosis Collapse << | Phase 3 | Withdrawn | August 2014 | - |
| NCT00893555 | Invasive Fungal Infection ... more >> Hematological Malignancy Collapse << | Phase 3 | Completed | - | Netherlands ... more >> University Medical Center Groningen Groningen, Netherlands, 9713GZ Collapse << |
| NCT01092832 | Candidiasis | Phase 3 | Terminated(This protocol termi... more >>nated prematurely on July 8, 2013 due to slow enrollment, not because of any safety issues or concerns.) Collapse << | - | China, Hubei ... more >> Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology Wuhan, Hubei, China, 430030 China Beijing Children's Hospital, Capital University of Medical Sciences Beijing, China, 100045 Czech Republic Fakultni nemocnice Brno - Klinika detske onkologie Brno, Czech Republic, 625 00 Hong Kong Department of Paediatrics and Adolescent Medicine Hong Kong, Hong Kong, 0 Queen Mary Hospital Hong Kong, Hong Kong The Chinese University of Hong Kong, Prince of Wales Hospital Shatin, N.T., Hong Kong Hungary Semmelweis Egyetem, II. sz. Szemeszeti Klinika Budapest, Hungary, 1085 Semmelweis Egyetem, II. sz. Gyermekgyogyaszati Klinika Budapest, Hungary, 1094 Fovarosi Onkormanyzat Egyesitett Szent Istvan és Szent Laszlo Korhaz-Rendelointezet Budapest, Hungary, 1097 Mexico Instituto Nacional de Pediatria Colonia Insurgentes Cuicuilco, Delegacion Coyoacan, DF, Mexico, 04530 Philippines Medical Research Laboratory Philippine General Hospital University of the Philippines Ermita,, Manila, Philippines, 1000 Rm. 112 ICHHD, National Institutes of Health-University of the Philippines Manila Manila, Philippines, 1000 Poland Oddzial Pediatryczny I- Hematologiczno-Onkologiczny Olsztyn, Poland, 10-561 Slovakia Detska fakultna nemocnica s poliklinikou Bratislava Bratislava, Slovakia, 833 40 Collapse << |
| NCT01539330 | Healthy | Phase 4 | Completed | - | Austria ... more >> Medical University of Vienna, Department of Clinical Pharmacology Vienna, Austria, 1090 Collapse << |
| NCT00792246 | Graft Versus Host Disease ... more >> Stem Cell Transplantation Collapse << | Phase 1 | Completed | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT02689713 | Pain Thermal ... more >>Injury Burns Hyperalgesia Collapse << | Phase 2 | Recruiting | June 2020 | United States, Texas ... more >> San Antonio Military Medical Center Recruiting San Antonio, Texas, United States, 78234 Contact: Christopher White, MD christopher.e.white34.mil@mail.mil Collapse << |
| NCT00300677 | Infections, Fungal | Phase 4 | Completed | - | United States, Massachusetts ... more >> Pfizer Investigational Site Belmont, Massachusetts, United States, 02478-1041 Collapse << |
| NCT00300677 | - | - | Completed | - | - |
| NCT01185405 | Invasive Fungal Infection | Not Applicable | Withdrawn | December 2013 | Korea, Republic of ... more >> Asan Medical Center Seoul, Korea, Republic of, 138-736 Collapse << |
| NCT02396225 | Invasive Aspergillosis | Not Applicable | Terminated(results obtained at... more >> interrim analysis after 12 patients would not be changed by recruiting another twelwe participants) Collapse << | - | Denmark ... more >> Aarhus University Hospital Aarhus C, Denmark, 8000 Collapse << |
| NCT00855101 | Healthy Volunteers | Phase 1 | Completed | - | Belgium ... more >> Pfizer Investigational Site Bruxelles, Belgium, 1070 Collapse << |
| NCT01480219 | - | - | Completed | - | - |
| NCT03760276 | Fungal Infection | Phase 1 | Completed | - | Korea, Republic of ... more >> Seoul National University Hospital Clinical Trial Center Seoul, Korea, Republic of, 03080 Collapse << |
| NCT03731169 | Aspergillosis Invasive ... more >> Fungal Infection Collapse << | Phase 4 | Recruiting | June 2019 | Canada, Ontario ... more >> Toronto General Hospital Recruiting Toronto, Ontario, Canada, M5G 2C4 Princess Margaret Cancer Care Centre Recruiting Toronto, Ontario, Canada, M5G 2M9 Collapse << |
| NCT02283905 | Blastomycosis | Phase 4 | Suspended(Manufacturer of amph... more >>otericin-B deoxycholate cannot supply at this time.) Collapse << | December 2018 | Canada, Manitoba ... more >> St. Boniface General Hospital Winnipeg, Manitoba, Canada, R2H 2A6 Collapse << |
| NCT01101386 | - | - | Completed | - | United States, Colorado ... more >> University of Colorado Hospital Aurora, Colorado, United States, 80045 Collapse << |
| NCT03067350 | - | - | Recruiting | October 2018 | France ... more >> University Hospital, Grenoble Alpes Recruiting Grenoble, France, 38043 Collapse << |
| NCT01030653 | Healthy | Phase 4 | Completed | - | United States, New Jersey ... more >> TKL Research Inc Paramus, New Jersey, United States, 07652 Collapse << |
| NCT01030653 | - | - | Completed | - | - |
| NCT02904434 | - | - | Recruiting | June 2020 | United States, Pennsylvania ... more >> Children's Hospital of Philadelphia Recruiting Philadelphia, Pennsylvania, United States, 19104 Contact: Athena Zuppa, MD 267-426-7359 zuppa@email.chop.edu Contact: Nicole Zane, PharmD, PhD 215.590.8797 zanen@email.chop.edu Collapse << |
| NCT01660334 | - | - | Completed | - | - |
| NCT01151085 | - | - | Completed | - | - |
| NCT02100761 | - | - | Unknown | June 2015 | China, Shandong ... more >> Qilu Hospital Not yet recruiting Jinan, Shandong, China, 250012 Contact: Shifang Ding, Ph.D. 18560081003 ext +86 dingshifang@sdu.edu.cn Principal Investigator: Shifang Ding, Ph.D. Collapse << |
| NCT01976078 | - | - | Completed | - | United States, California ... more >> Children's Hospital Los Angeles Los Angeles, California, United States, 90027 Collapse << |
| NCT01151085 | - | - | Completed | - | - |
| NCT01887457 | Immunocompromised Patient ... more >> Aspergillosis Fusarium Collapse << | Phase 2 | Suspended(Transfer of manageme... more >>nt of study) Collapse << | December 2016 | United Kingdom ... more >> The Christie NHS Foundation Trust Manchester, United Kingdom, M20 4BX Collapse << |
| NCT02234739 | Invasive Pulmonary Aspergillos... more >>is COPD Collapse << | Phase 4 | Unknown | December 2016 | China, Zhejiang ... more >> Hangzhou Red Cross Hospital Not yet recruiting Hangzhou, Zhejiang, China, 310003 Contact: Chuang Cai, doctor 86-0571-56109772 tinattm@163.com Sub-Investigator: Enguo Chen, doctor Sub-Investigator: Limin Wang, master Sub-Investigator: Qun Nv, bachelor Sub-Investigator: Rongzhuan Zhao, bachelor Sub-Investigator: YongChen Li, bachelor Sub-Investigator: Xiaoping Huang, bachelor Sub-Investigator: Bin Wang, bachelor Sub-Investigator: jianping Yan, bachelor Sub-Investigator: jianpu Xu, bachelor Collapse << |
| NCT03260634 | - | - | Active, not recruiting | January 1, 2018 | Thailand ... more >> Chulalongkorn university Bangkok, Thailand, 10330 Collapse << |
| NCT01660334 | - | - | Completed | - | - |
| NCT02110316 | Voriconazole ... more >>Bioavailability Critically Ill Collapse << | Phase 4 | Withdrawn(no eligible patients... more >>; study stopped without inclusion) Collapse << | - | Netherlands ... more >> University Medical Center Groningen Groningen, Netherlands, 9700 RB Collapse << |
