CAS No.: 91940-87-3
Zatebradine HCl Catalog No. CSN18579
Synonyms: UL-FS-49;UL-FS-49CL;UL-FS-49 HCl
Zatebradine HCl is a potent HCN channels antagonist, which decreased the heartbeat in a reversible manner with 92% inhibition of the hHCN1-mediated current at 10 μM.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Matt L, Michalakis S, et al. HCN2 channels in local inhibitory interneurons constrain LTP in the hippocampal direct perforant path. Cell Mol Life Sci. 2011 Jan;68(1):125-37.
- [2] Gill CH, Randall A, et al. Characterization of the human HCN1 channel and its inhibition by capsazepine. Br J Pharmacol. 2004 Oct;143(3):411-21.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 91940-87-3 | 储存条件 |
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| 分子式 | C26H37ClN2O5 | 运输 | 蓝冰 | |
| 分子量 | 493.04 | 别名 | UL-FS-49;UL-FS-49CL;UL-FS-49 HCl;Zatebradine (hydrochloride);Zatebradine HCl;Zatebradine Hydrochloride |
