CAS No.: 138982-67-9
Ziprasidone HCl monohydrate/佐帕司通 Catalog No. CSN12812
Synonyms: CP 88059 hydrochloride monohydrate;CP-88059;Ziprasidone (hydrochloride hydrate)
Ziprasidone HCl H2O is a full antagonist of D2 receptors and of 5-HT2A receptors and is a partial agonist of 5-HT1A receptors, of 5-HT2C receptors and 5-HT1D receptors, used as an atypical antipsychoticfor the treatment of schizophrenia as well as acute mania and mixed states associated with bipolar disorder.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT01185743 Schizophrenia ... more >> Diabetes Collapse << Phase 4 Completed - Austria ... more >> Medical University of Vienna Vienna, Austria, 1090 Collapse << NCT00538629 - - Completed - - NCT01598324 - - Terminated(Clinical trial from... more >> which subjects were recruited closed to enrollment) Collapse << - United States, Massachusetts ... more >> McLean Hospital - McLean Imaging Center Belmont, Massachusetts, United States, 02478 Collapse << - 更多
- 参考文献
- [1] Ravikiran A, Arthanareeswari M, et al. Nonisothermal kinetics analysis of the dehydration of ziprasidone hydrochloride monohydrate by thermogravimetry. Indian J Pharm Sci. 2013 May;75(3):361-4.
- [2] Rollema H, Lu Y, Schmidt AW, Sprouse JS, Zorn SH. 5-HT(1A) receptor activation contributes to ziprasidone-induced dopamine release in the rat prefrontal cortex. Biol Psychiatry. 2000 Aug 1;48(3):229-37
- [3] Seeger TF, Seymour PA, Schmidt AW, Zorn SH, Schulz DW, Lebel LA, McLean S, Guanowsky V, Howard HR, Lowe JA 3rd, et al. Ziprasidone (CP-88,059): a new antipsychotic with combined dopamine and serotonin receptor antagonist activity. J Pharmacol Exp Ther. 1995 Oct;275(1):101-13
- [4] Patel NC, Keck PE Jr. Ziprasidone: efficacy and safety in patients with bipolar disorder. Expert Rev Neurother. 2006 Aug;6(8):1129-38
- [5] Gunasekara NS, Spencer CM, Keating GM. Ziprasidone: a review of its use in schizophrenia and schizoaffective disorder. Drugs. 2002;62(8):1217-51
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 138982-67-9 | 储存条件 |
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| 分子式 | C21H24Cl2N4O2S | 运输 | 蓝冰 | |||||
| 分子量 | 467.41 | 别名 | CP 88059 hydrochloride monohydrate;CP-88059;Ziprasidone (hydrochloride hydrate);CP-88,059;Ziprasidone HCl hydrate;CP-88,059-01;CP88059 hydrochloride;Ziprasidone HCl,;盐酸齐拉西酮水合物 | |||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
|---|
| NCT01185743 | Schizophrenia ... more >> Diabetes Collapse << | Phase 4 | Completed | - | Austria ... more >> Medical University of Vienna Vienna, Austria, 1090 Collapse << |
| NCT00538629 | - | - | Completed | - | - |
| NCT01598324 | - | - | Terminated(Clinical trial from... more >> which subjects were recruited closed to enrollment) Collapse << | - | United States, Massachusetts ... more >> McLean Hospital - McLean Imaging Center Belmont, Massachusetts, United States, 02478 Collapse << |
| NCT03011645 | Cardiovascular Diseases | Phase 1 | Enrolling by invitation | November 2022 | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00288366 | Schizophrenia ... more >> Schizoaffective Disorder Bipolar Disorder Collapse << | Not Applicable | Completed | - | United States, Tennessee ... more >> Psychiatric Hospital at Vanderbilt Nashville, Tennessee, United States, 37212 Collapse << |
| NCT00197951 | Depression An... more >>ger Anxiety Alcoholism Collapse << | Phase 3 | Completed | - | Spain ... more >> Unidad de Conductas Adictivas//Servicio de Psiquiatría//Hospital de la Santa Creu i Sant Pau Barcelona, Spain, 08025 Collapse << |
| NCT00159770 | Schizophrenia ... more >> Schizoaffective Disorder Psychotic Disorders Collapse << | Phase 3 | Completed | - | - |
| NCT01844700 | - | - | Terminated(very slow recruitme... more >>nt, no sufficient results) Collapse << | - | - |
| NCT00538629 | - | - | Completed | - | - |
| NCT01893229 | Bipolar Disorder | Phase 4 | Unknown | December 2015 | China, Guangdong ... more >> Guangzhou Psychiatric Hospital Enrolling by invitation Guangzhou, Guangdong, China, 510370 Guangzhou Psychiatric Hospital Recruiting Guangzhou, Guangdong, China, 510370 Contact: Guiyun Xu, M.D xuguiyun2908@hotmail.com Principal Investigator: Guiyun Xu, M.D Collapse << |
| NCT01844700 | High Risk MC4R Genotype ... more >> Low Risk MC4R Genotype One Week or Less Antipsychotic Lifetime Exposure Collapse << | Phase 4 | Terminated(very slow recruitme... more >>nt, no sufficient results) Collapse << | - | United States, New York ... more >> Zucker Hillside Hospital, Psychiatry Research Glen Oaks, New York, United States, 11004 Collapse << |
| NCT00297960 | Healthy Male Volunteers | Phase 4 | Completed | - | Austria ... more >> Department of Clinical Pharmacology, Medical University Vienna Vienna, Austria, 1090 Collapse << |
| NCT01211522 | Delirium Impa... more >>ired Cognition Long Term Psychologic Disorders Collapse << | Phase 3 | Active, not recruiting | July 15, 2025 | United States, Colorado ... more >> Denver Health/University of Colorado Health Sciences Center Denver, Colorado, United States, 80204-4507 United States, Connecticut Yale University Medical Center New Haven, Connecticut, United States, 06520-8057 United States, Indiana Indiana University Indianapolis, Indiana, United States, 46202-2915 United States, Iowa University of Iowa Iowa City, Iowa, United States, 52242 United States, Maryland University of Maryland Medical Center Baltimore, Maryland, United States, 21201 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114-2696 Brigham and Women's Hospital Boston, Massachusetts, United States, 02115 United States, Michigan University of Michigan Health System Ann Arbor, Michigan, United States, 48109-5360 United States, New York Albert Einstein Medical College-Montefiore Medical Center Bronx, New York, United States, 10461 United States, North Carolina University of North Carolina - Chapel Hill Chapel Hill, North Carolina, United States, 27599-7248 Moses Cone Health System Greensboro, North Carolina, United States, 27410 United States, Ohio The Ohio State Medical Center Columbus, Ohio, United States, 43210-1228 United States, Pennsylvania University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-6205 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37232-8300 United States, Texas Baylor Health Care System Dallas, Texas, United States, 75206 United States, Washington University of Washington Seattle, Washington, United States, 98195-9472 Collapse << |
| NCT00148564 | Schizophrenia | Phase 4 | Completed | - | Germany ... more >> Charité Universitaetsmedizin Berlin; Campus Charité Mitte; Dept. for Psychiatry and Psychotherapy Berlin, Germany, 10117 Collapse << |
| NCT02534363 | Schizophrenia ... more >> Psychotic Disorders Collapse << | Phase 4 | Completed | - | Spain ... more >> University Hospital Marqués de Valdecilla Santander, Cantabria, Spain, 39008 Collapse << |
| NCT00141271 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT00136994 | Schizophrenia | Phase 3 | Completed | - | Italy ... more >> Pfizer Investigational Site Savigliano, Cuneo, Italy, 12038 Pfizer Investigational Site Campi Bisenzio, Firenze, Italy, 50013 Pfizer Investigational Site Sora, Frosinone, Italy, 3039 Pfizer Investigational Site Parma, PR, Italy, 43100 Pfizer Investigational Site S. Arsenio, Salerno, Italy, 84037 Pfizer Investigational Site Bologna, Italy, 40100 Pfizer Investigational Site Cagliari, Italy, 09100 Pfizer Investigational Site Caserta, Italy, 81100 Pfizer Investigational Site Chiari (bs), Italy, 25032 Pfizer Investigational Site Cremona, Italy, 26100 Pfizer Investigational Site Fidenza(pr), Italy, 43036 Pfizer Investigational Site Foggia, Italy, 71100 Pfizer Investigational Site Genova-sestri, Italy, 16154 Pfizer Investigational Site Genova, Italy, 16132 Pfizer Investigational Site Lecce, Italy, 73100 Pfizer Investigational Site Milano, Italy, 20142 Pfizer Investigational Site Modena, Italy, 41100 Pfizer Investigational Site Moncalieri(to), Italy, 10024 Pfizer Investigational Site Napoli, Italy, 80136 Pfizer Investigational Site Noto, Italy, 96017 Pfizer Investigational Site Orbassano (to), Italy, 10043 Pfizer Investigational Site Padova, Italy, 35128 Pfizer Investigational Site Palermo, Italy, 90145 Pfizer Investigational Site Perugia, Italy, 06100 Pfizer Investigational Site Pordenone, Italy, 33170 Pfizer Investigational Site Roma, Italy, 00149 Pfizer Investigational Site Sassari, Italy, 07100 Pfizer Investigational Site Senigallia (an), Italy, 60019 Pfizer Investigational Site Torino, Italy, 10126 Pfizer Investigational Site Torino, Italy, 10154 Pfizer Investigational Site Torrette Di Ancona (an), Italy, 60020 Pfizer Investigational Site Udine, Italy, 33100 Pfizer Investigational Site Verona, Italy, 37063 Pfizer Investigational Site Viareggio, Italy, 55049 Collapse << |
| NCT00239109 | Schizophrenia | Phase 4 | Completed | - | Spain ... more >> Pfizer Investigational Site Bilbao, Vizcaya, Spain Pfizer Investigational Site Badajoz, Spain Pfizer Investigational Site Barcelona, Spain Pfizer Investigational Site Madrid, Spain Pfizer Investigational Site Salamanca, Spain Pfizer Investigational Site Sevilla, Spain Pfizer Investigational Site Zamora, Spain Collapse << |
| NCT00141271 | - | - | Completed | - | - |
| NCT00224315 | Schizophrenia, Schizoaffective... more >> Disorder Collapse << | Phase 4 | Completed | - | Germany ... more >> Central Institute of Mental Health, Department of Psychiatry, Mannheim, BW, Germany, 68159 Collapse << |
| NCT00137020 | Schizophrenia ... more >> Psychotic Disorders Collapse << | Phase 4 | Completed | - | Egypt ... more >> Pfizer Investigational Site Alexandria, Egypt Pfizer Investigational Site Assiut, Egypt Pfizer Investigational Site Cairo, Egypt Pfizer Investigational Site Tanta, Egypt Greece Pfizer Investigational Site Larissa, Mezourlo, Greece, 41110 Pfizer Investigational Site Athens, Greece, 11528 Pfizer Investigational Site Athens, Greece, 12462 Pfizer Investigational Site Athens, Greece, 15126 Jordan Pfizer Investigational Site Jordan, Jordan Kuwait Pfizer Investigational Site Kuwait, Kuwait, 13041 Lebanon Pfizer Investigational Site Beirut, Lebanon Saudi Arabia Pfizer Investigational Site Khobar, Saudi Arabia, 31451 South Africa Pfizer Investigational Site Garankuwa, Gauteng, South Africa, 0208 Pfizer Investigational Site Krugersdorp, Gauteng, South Africa, 1739 Pfizer Investigational Site Noordheuwel, Krugersdorp, Gauteng, South Africa, 1739 Pfizer Investigational Site Bellair, Durban, Kwa-Zulu Natal, South Africa, 4094 Pfizer Investigational Site Pinetown, Durban, Kwa-Zulu Natal, South Africa, 3600 Pfizer Investigational Site Observatory, Cape Town, Western Cape, South Africa, 7925 Turkey Pfizer Investigational Site Ankara, Turkey Pfizer Investigational Site Bursa, Turkey Pfizer Investigational Site Erzurum, Turkey Pfizer Investigational Site Istanbul, Turkey Pfizer Investigational Site Izmir, Turkey, 35340 Pfizer Investigational Site Izmir, Turkey Pfizer Investigational Site Manisa, Turkey Pfizer Investigational Site Sisli, Turkey United Arab Emirates Pfizer Investigational Site Dubai, United Arab Emirates Collapse << |
| NCT00174447 | Schizophrenia | Phase 3 | Completed | - | France ... more >> Pfizer Investigational Site Avignon, France, 84000 Pfizer Investigational Site Dole Saint Ylie, France, 39108 Pfizer Investigational Site Lievin, France, 62800 Pfizer Investigational Site Lyon Cedex, France, 69373 Pfizer Investigational Site Montfavet, France, 84143 Pfizer Investigational Site Orvault, France, 44700 Pfizer Investigational Site Rennes, France, 35000 Pfizer Investigational Site Saint Egreve Cedex, France, 38521 Pfizer Investigational Site Saint Remy, France, 70160 Pfizer Investigational Site Strasbourg, France, 67100 Pfizer Investigational Site Toulon Cedex, France, 83056 Pfizer Investigational Site Toulouse, France, 31000 Pfizer Investigational Site Toulouse, France, 31200 Pfizer Investigational Site Versailles, France, 78000 Collapse << |
| NCT00645372 | Schizophrenia | Phase 3 | Completed | - | China ... more >> Pfizer Investigational Site Beijing, China, 100083 Pfizer Investigational Site Beijing, China, 100088 Pfizer Investigational Site Guangzhou, China, 510370 Pfizer Investigational Site Nanjing, China, 210029 Pfizer Investigational Site Shanghai, China, 200030 Collapse << |
| NCT00229385 | Schizophrenia ... more >> Obsessive Compulsive Disorder Collapse << | Not Applicable | Completed | - | Israel ... more >> Chaim Sheba Medical Center Ramat-Gan, Israel, 52621 Collapse << |
| NCT00174447 | - | - | Completed | - | - |
| NCT00159757 | Schizophrenia | Phase 4 | Terminated(See Detailed Descri... more >>ption for Termination Reason) Collapse << | - | Hungary ... more >> Pfizer Investigational Site Budapest, Hungary Pfizer Investigational Site Debrecen, Hungary Pfizer Investigational Site Esztergom, Hungary Pfizer Investigational Site Kecskemet, Hungary Pfizer Investigational Site Kistarcsa, Hungary Pfizer Investigational Site Pecs, Hungary Pfizer Investigational Site Szekesfehervar, Hungary Pfizer Investigational Site Tatabanya, Hungary Collapse << |
| NCT00181922 | Bipolar Disorder ... more >> Mania Collapse << | Phase 4 | Completed | - | United States, Massachusetts ... more >> Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Massachusetts General Hospital Cambridge, Massachusetts, United States, 02138 Collapse << |
| NCT00143351 | Schizophrenia | Phase 3 | Completed | - | Italy ... more >> Pfizer Investigational Site Vicenza, Bassano Del Grappa, Italy, 36061 Pfizer Investigational Site Citta' Di Castello, Perugia, Italy, 06012 Pfizer Investigational Site Bari, Italy, 70100 Pfizer Investigational Site Brescia, Italy, 25100 Pfizer Investigational Site Catania, Italy, 95123 Pfizer Investigational Site Guardiagrele (ch), Italy, 66016 Pfizer Investigational Site Messina, Italy, 98100 Pfizer Investigational Site Parma, Italy, 43100 Pfizer Investigational Site Roma, Italy, 00100 Pfizer Investigational Site Roma, Italy, 00135 Pfizer Investigational Site Roma, Italy, 00137 Pfizer Investigational Site Sassari, Italy, 07100 Pfizer Investigational Site Terni, Italy Pfizer Investigational Site Torino, Italy, 10126 Pfizer Investigational Site Trieste, Italy, 34126 Pfizer Investigational Site Verona, Italy, 37100 Collapse << |
| NCT00265330 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT01260116 | - | - | Unknown | March 2012 | - |
| NCT03211897 | - | - | Completed | - | United States, Minnesota ... more >> Hennepin County Medical Center Minneapolis, Minnesota, United States, 55415 Collapse << |
| NCT02526030 | Schizophrenia ... more >> Psychotic Disorders Collapse << | Phase 4 | Completed | - | Spain ... more >> University Hospital Marqués de Valdecilla Santander, Cantabria, Spain, 39008 Collapse << |
| NCT00199940 | Schizophrenia ... more >> Affective Disorders Psychotic Disorder Psychotic Mood Disorder Collapse << | Phase 4 | Completed | - | - |
| NCT00338949 | Schizophrenia ... more >> Metabolic Syndrome X Insulin Resistance Collapse << | Phase 4 | Completed | - | United States, California ... more >> VA San Diego Healthcare System San Diego, California, United States, 92161 Collapse << |
| NCT00257166 | - | - | Completed | - | - |
| NCT00205725 | Schizophrenia ... more >> Type 2 Diabetes Mellitus Collapse << | Not Applicable | Completed | - | United States, Missouri ... more >> Washington University School of Medicine, Psychiatry Dept. St. Louis, Missouri, United States, 63110 Collapse << |
| NCT00634348 | Schizophrenia | Phase 4 | Completed | - | - |
| NCT02305823 | Schizophrenia ... more >> Psychotic Disorders Collapse << | Phase 4 | Completed | - | Spain ... more >> University Hospital Marques de Valdecilla Santander, Cantabria, Spain, 39008 Collapse << |
| NCT00248261 | - | - | Terminated(High rate of early ... more >>drop-outs) Collapse << | - | Germany ... more >> UKE, Dept. of Psychiatry and Psychotherapy Hamburg, Germany, 2ß246 Collapse << |
| NCT01157559 | First Episode Psychosis | Phase 4 | Completed | - | Korea, Republic of ... more >> Department of Psychiatry, Chonbuk national University Hospital Jeonju, Korea, Republic of Heo psychiatric Hospital Jeonju, Korea, Republic of Jeonju Jesus Hospital Jeonju, Korea, Republic of Collapse << |
| NCT00257166 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT00418171 | Schizophrenia | Phase 4 | Completed | - | United States, California ... more >> Pfizer Investigational Site San Bernardino, California, United States United States, Hawaii Pfizer Investigational Site Aiea, Hawaii, United States United States, Illinois Pfizer Investigational Site Schaumburg, Illinois, United States United States, Oregon Pfizer Investigational Site Grants Pass, Oregon, United States United States, West Virginia Pfizer Investigational Site Whitehall, West Virginia, United States Collapse << |
| NCT00786318 | Psychosis Agi... more >>tation Delirium Collapse << | Phase 4 | Withdrawn(Sponsor terminated) | July 2011 | United States, District of Col... more >>umbia The George Washington University Medical Center, Dept of Emergency Medicine Washington, D.C., District of Columbia, United States, 20037 Collapse << |
| NCT00340379 | Affective Disorders | Phase 2 Phase 3 | Completed | - | United States, California ... more >> University of Southern California Los Angeles, California, United States, 90033 Egypt Alexandria University Alexandria, Egypt India National Institute of Mental Health and Neuroscience Bangalore, India, 560029 Collapse << |
| NCT00265330 | - | - | Completed | - | - |
| NCT00340379 | - | - | Completed | - | - |
| NCT00351000 | Schizophrenia | Phase 4 | Completed | - | United States, Massachusetts ... more >> Freedom Trail Clinic Boston, Massachusetts, United States, 02114 Collapse << |
| NCT00645515 | Schizophrenia | Phase 3 | Terminated(This study was term... more >>inated on November 20, 2003 because of poor recruitment. This study was not terminated due to safety/efficacy.) Collapse << | - | Spain ... more >> Pfizer Investigational Site Bilbao, Vizcaya, Spain, 48010 Pfizer Investigational Site Getxo, Vizcaya, Spain, 48990 Pfizer Investigational Site Madrid, Spain, 28007 Collapse << |
| NCT00649844 | Schizophrenia | Phase 3 | Completed | - | Italy ... more >> Pfizer Investigational Site Citta' Di Castello, Perugia, Italy, 06012 Pfizer Investigational Site Bassano Del Grappa, Vicenza, Italy, 36061 Pfizer Investigational Site Bari, Italy, 70124 Pfizer Investigational Site Brescia, Italy, 25100 Pfizer Investigational Site Cagliari, Italy, 09045 Pfizer Investigational Site Cagliari, Italy, 09124 Pfizer Investigational Site Catania, Italy, 95123 Pfizer Investigational Site Firenze, Italy, 50134 Pfizer Investigational Site Guardiagrele (ch), Italy, 66016 Pfizer Investigational Site Messina, Italy, 98100 Pfizer Investigational Site Montichiari (brescia), Italy, 25018 Pfizer Investigational Site Napoli, Italy, 80131 Pfizer Investigational Site Parma, Italy, 43100 Pfizer Investigational Site Reggio Calabria, Italy, 89100 Pfizer Investigational Site Roma, Italy, 00135 Pfizer Investigational Site Roma, Italy, 00137 Pfizer Investigational Site Sassari, Italy, 07100 Pfizer Investigational Site Siena, Italy, 53100 Pfizer Investigational Site Torino, Italy, 10126 Pfizer Investigational Site Trieste, Italy, 34126 Pfizer Investigational Site Verona, Italy, 37126 Collapse << |
| NCT00282464 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT00351000 | - | - | Completed | - | - |
| NCT00282464 | - | - | Completed | - | - |
| NCT02075047 | Bipolar Disorder | Phase 3 | Recruiting | October 4, 2020 | - |
| NCT00145444 | Schizophrenia ... more >> Psychotic Disorders Collapse << | Phase 3 | Completed | - | Belgium ... more >> Pfizer Investigational Site Antwerpen, Belgium, B-2060 Pfizer Investigational Site Duffel, Belgium, B-2570 Pfizer Investigational Site Kortenberg, Belgium, B-3070 Netherlands Pfizer Investigational Site Ermelo, Netherlands, NL-3851 PB Pfizer Investigational Site Groningen, Netherlands, NL-9713 GZ Pfizer Investigational Site Nijmegen, Netherlands, NL-6525 GC Pfizer Investigational Site Utrecht, Netherlands, 3584 CX Collapse << |
| NCT00312494 | - | - | Completed | - | - |
| NCT00257192 | Schizophrenia | Phase 3 | Terminated(Please see Detailed... more >> Description for termination reason.) Collapse << | - | - |
| NCT00329108 | - | - | Terminated(Please see Brief Su... more >>mmary for Termination Reason.) Collapse << | - | - |
| NCT00257192 | - | - | Terminated(Please see Detailed... more >> Description for termination reason.) Collapse << | - | - |
| NCT00208208 | Posttraumatic Stress Disorder ... more >> Post-Traumatic Stress Disorder PTSD Collapse << | Phase 4 | Completed | - | United States, Nebraska ... more >> Creighton University Psychiatry and Research Center Omaha, Nebraska, United States, 68131 Collapse << |
| NCT00312494 | Bipolar Disorder | Phase 3 | Completed | - | - |
| NCT00329108 | Acute Mania B... more >>ipolar Disorder, Manic Collapse << | Phase 4 | Terminated(Please see Brief Su... more >>mmary for Termination Reason.) Collapse << | - | Germany ... more >> Pfizer Investigational Site Aachen, Germany, 52074 Pfizer Investigational Site Augsburg, Germany, 86156 Pfizer Investigational Site Freiburg, Germany, 79104 Greece Pfizer Investigational Site Athens, Greece, 124 62 Italy Pfizer Investigational Site S. Arsenio, Salerno, Italy, 84037 Pfizer Investigational Site Bari, Italy, 70100 Pfizer Investigational Site Guardiagrele (CH), Italy, 66016 Pfizer Investigational Site Lido di Camaiore (LU), Italy, 55043 Pfizer Investigational Site Partinico (Pa), Italy, 90047 Pfizer Investigational Site Perugia, Italy, 06127 Pfizer Investigational Site Siena, Italy, 53100 Pfizer Investigational Site Torino, Italy, 10126 Pfizer Investigational Site Trieste, Italy, 34126 Spain Pfizer Investigational Site Terrassa, Barcelona, Spain, 08227 Pfizer Investigational Site Alava, Vitoria, Spain, 01004 Pfizer Investigational Site Granada, Spain, 18014 Pfizer Investigational Site Malaga, Spain, 29009 Turkey Pfizer Investigational Site Ankara, Turkey, 06100 Pfizer Investigational Site Istanbul, Turkey, 34440 Collapse << |
| NCT01117220 | Bipolar Disorder | Phase 3 | Withdrawn | April 2011 | - |
| NCT00821444 | Healthy | Phase 1 | Completed | - | United States, Connecticut ... more >> Pfizer Investigational Site New Haven, Connecticut, United States, 06511-5473 Collapse << |
| NCT01172652 | Bipolar Disorder ... more >> Panic Disorder Generalized Anxiety Disorder Collapse << | Phase 4 | Completed | - | United States, California ... more >> VA Palo Alto Health Care System & Stanford School of Medicine Palo Alto, California, United States, 94304 United States, Florida University of South Florida Institute for Research in Psychiatry Tampa, Florida, United States, 33613 United States, Ohio Lindner Center of Hope University of Cincinnati Medical Center Mason, Ohio, United States, 45040 Collapse << |
| NCT00635700 | - | - | Completed | - | - |
| NCT00635921 | Borderline Personality Disorde... more >>r Collapse << | Phase 2 | Completed | - | Spain ... more >> Department of Psychiatry, Sta. Creu and St. Pau Hospital Barcelona., Spain, 08025 Collapse << |
| NCT00265382 | Schizophrenia | Phase 3 | Terminated(Please see Detailed... more >> Description for termination reason.) Collapse << | - | - |
| NCT00421954 | - | - | Completed | - | - |
| NCT00421954 | Schizophreniform Disorder ... more >> Schizoaffective Disorder Psychosis Depressive Disorder, Major Bipolar Disorder Collapse << | Phase 3 | Completed | - | United States, New York ... more >> NYSPI New York, New York, United States, 10032 Collapse << |
| NCT00676429 | Conduct Disorder ... more >> Oppositional Defiant Disorder Collapse << | Phase 2 | Completed | - | Germany ... more >> University Hospital Freiburg, Dep. for Child & Adolescent Psychiatry Freiburg, Germany, D-79104 Collapse << |
| NCT00818298 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Not Applicable | Completed | - | Canada, Ontario ... more >> Centre for Addiction and Mental Health - PET Centre Toronto, Ontario, Canada, M5T 1R8 Collapse << |
| NCT00723606 | - | - | Completed | - | - |
| NCT00633399 | - | - | Completed | - | - |
| NCT00650429 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 4 | Completed | - | Mexico ... more >> Pfizer Investigational Site Monterrey, Nuevo Leon, Mexico, 64800 Pfizer Investigational Site DF, Mexico, 14420 Pfizer Investigational Site Mexico City, Mexico, 14050 Pfizer Investigational Site Mexico D F, Mexico, 14269 Collapse << |
| NCT00265382 | - | - | Terminated(Please see Detailed... more >> Description for termination reason.) Collapse << | - | - |
| NCT00644800 | Schizophrenia ... more >> Mania Delusional Disorder Acute Exacerbation of Psychosis Collapse << | Phase 4 | Completed | - | Brazil ... more >> Pfizer Investigational Site Salvador, Bahia, Brazil, 41180-000 Pfizer Investigational Site Fortaleza, Ceara, Brazil, 60175-270 Pfizer Investigational Site Belo Horizonte, MG, Brazil, 30150-270 Pfizer Investigational Site Curitiba, PR, Brazil Pfizer Investigational Site Rio de Janeiro, RJ, Brazil Pfizer Investigational Site Sao Goncalo, RJ, Brazil Pfizer Investigational Site Jardim Santa Monica Sn, Salvador - Ba, Brazil, 40340-720 Pfizer Investigational Site Sao Paulo, SP, Brazil Collapse << |
| NCT00633399 | Major Depressive Disorder | Phase 2 | Completed | - | United States, Alabama ... more >> University of Alabama at Birmingham Birmingham, Alabama, United States, 35294 United States, Massachusetts Massachusetts General Hospital- Depression Clinical and Research Program Boston, Massachusetts, United States, 02114 Collapse << |
| NCT01124877 | Bipolar Disorder | Phase 3 | Withdrawn | October 2011 | - |
| NCT00635700 | Psychosis Prodrome | Phase 2 | Completed | - | United States, California ... more >> University of California at San Diego La Jolla, California, United States, 92093 University of California at Los Angeles Los Angeles, California, United States, 90095 University of California, San Francisco San Francisco, California, United States, 94143 United States, Connecticut Yale University School of Medicine New Haven, Connecticut, United States, 06519 United States, Georgia Emory University Atlanta, Georgia, United States, 30322 United States, Massachusetts Beth Israel Deaconess Hospital Boston, Massachusetts, United States, 02215 University of Massachusetts Worcester, Massachusetts, United States, 01604 United States, Michigan Wayne State University School of Medicine Detroit, Michigan, United States, 48201 United States, New York North Shore, Long Island Jewish Health System Glen Oaks, New York, United States, 11004 United States, North Carolina University of North Carolina Chapel Hill, North Carolina, United States, 27599 Canada, Alberta University of Calgary Calgary, Alberta, Canada, T2N2T9 Collapse << |
| NCT00645229 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 3 | Terminated(Please see Detailed... more >> Description for termination reason.) Collapse << | - | Portugal ... more >> Pfizer Investigational Site Lisboa, Portugal, 1600-219 Collapse << |
| NCT00723606 | Schizophrenia | Phase 3 | Completed | - | China, Hebei ... more >> Pfizer Investigational Site Baoding, Hebei, China, 071000 China, Hubei Pfizer Investigational Site Wuhan, Hubei, China, 430060 China, Yunnan Pfizer Investigational Site Kunming, Yunnan, China, 650032 China Pfizer Investigational Site Beijing, China, 100083 Pfizer Investigational Site Beijing, China, 100088 Pfizer Investigational Site Chang Sha, China, 410011 Pfizer Investigational Site Guangzhou, China, 510370 Pfizer Investigational Site Nanjing, China, 210029 Pfizer Investigational Site Xi'an, China Collapse << |
| NCT00406315 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 4 | Completed | - | - |
| NCT00280566 | - | - | Completed | - | - |
| NCT00406315 | - | - | Completed | - | - |
| NCT00139737 | - | - | Completed | - | - |
| NCT00139737 | Schizophrenia | Phase 3 | Completed | - | - |
| NCT00280566 | Bipolar Mania ... more >> Bipolar Disorder Collapse << | Phase 3 | Completed | - | - |
| NCT00490542 | Bipolar Disorder ... more >> Bipolar Depression Depression Collapse << | Phase 2 | Completed | - | United States, Illinois ... more >> Northwestern University Chicago, Illinois, United States, 60201 United States, Massachusetts Tufts University Boston, Massachusetts, United States, 02111 Cambridge Health Alliance Cambridge, Massachusetts, United States, 02139 United States, North Carolina Duke University Durham, North Carolina, United States, 27704 Collapse << |
| NCT00490542 | - | - | Completed | - | - |
| NCT00458211 | - | - | Completed | - | - |
| NCT00454883 | - | - | Completed | - | - |
| NCT00645320 | Pyschotic Disorders | Phase 4 | Completed | - | Brazil ... more >> Pfizer Investigational Site Salvador, Bahia, Brazil, 41180-000 Pfizer Investigational Site Fortaleza, Ceara, Brazil, 60175-270 Pfizer Investigational Site Belo Horizonte, MG, Brazil, 30150-270 Pfizer Investigational Site Curitiba, PR, Brazil Pfizer Investigational Site Rio de Janeiro, RJ, Brazil Pfizer Investigational Site Jardim Santa Monica Sn, Salvador - Ba, Brazil, 40340-720 Pfizer Investigational Site Sao Paulo, SP, Brazil Pfizer Investigational Site Rio de Janeiro Rj, Brazil, 22640-100 Collapse << |
| NCT00483548 | Bipolar Disorder ... more >> Depression, Bipolar Collapse << | Phase 3 | Completed | - | - |
| NCT00215150 | Social Anxiety Disorder | Phase 2 | Completed | - | United States, North Carolina ... more >> Duke University Medical Center Durham, North Carolina, United States, 27701 Duke University Medical Center Durham, North Carolina, United States, 27710 Collapse << |
| NCT00215150 | - | - | Completed | - | - |
| NCT00472641 | - | - | Completed | - | - |
| NCT00225498 | Schizophrenia | Not Applicable | Completed | - | United States, New York ... more >> The Zucker Hillside Hospital Glen Oaks, New York, United States, 11004 Collapse << |
| NCT00208559 | Autism | Phase 2 | Completed | - | United States, Pennsylvania ... more >> Drexel University College of Medicine at Friends Hospital Philadelphia, Pennsylvania, United States, 19124 Collapse << |
| NCT00483548 | - | - | Completed | - | - |
| NCT00225498 | - | - | Completed | - | - |
| NCT00910988 | Hyperglycemia ... more >> Hyperlipidemia Collapse << | Not Applicable | Completed | - | United States, Missouri ... more >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 Collapse << |
| NCT00910988 | - | - | Completed | - | - |
| NCT00374543 | Generalized Anxiety Disorder ... more >> Bipolar Disorder Collapse << | Phase 4 | Terminated(Recruitment goal co... more >>uld not be achieved) Collapse << | - | United States, Massachusetts ... more >> Center for Anxiety and Traumatic Stress Disorders at Massachusetts General Hospital Boston, Massachusetts, United States, 02114 Collapse << |
| NCT01168674 | Depression Bi... more >>polar Disorder Collapse << | Phase 4 | Completed | - | - |
| NCT00472641 | Bipolar Disorder | Phase 4 | Completed | - | United States, California ... more >> Stanford University School of Medicine Stanford, California, United States, 94305 Collapse << |
| NCT01168674 | - | - | Completed | - | - |
| NCT00458211 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 4 | Completed | - | United States, New York ... more >> Bronx Psychiatric Center Bronx, New York, United States, 10461 Buffalo Psychiatric Center Buffalo, New York, United States, 14213 Collapse << |
| NCT00650611 | Schizophrenia ... more >> Bipolar Disorder Schizoaffective Disorder Collapse << | Phase 2 | Completed | - | United States, California ... more >> Pfizer Investigational Site San Diego, California, United States, 92111 United States, Florida Pfizer Investigational Site Altamonte Springs, Florida, United States, 32701 United States, Illinois Pfizer Investigational Site Libertyville, Illinois, United States, 60048 United States, Kentucky Pfizer Investigational Site Lexington, Kentucky, United States, 40509 United States, Massachusetts Pfizer Investigational Site Belmont, Massachusetts, United States, 02478 Pfizer Investigational Site Brighton, Massachusetts, United States, 02135 United States, Nevada Pfizer Investigational Site Las Vegas, Nevada, United States, 89103 Pfizer Investigational Site Las Vegas, Nevada, United States, 89117 Pfizer Investigational Site Las Vegas, Nevada, United States, 89128 United States, New Jersey Pfizer Investigational Site Turnersville, New Jersey, United States, 08012 United States, Ohio Pfizer Investigational Site Cincinnati, Ohio, United States, 45224 Pfizer Investigational Site Cincinnati, Ohio, United States, 45229 Pfizer Investigational Site Cincinnati, Ohio, United States, 45267-0559 Pfizer Investigational Site Cleveland, Ohio, United States, 44106 United States, Pennsylvania Pfizer Investigational Site Philadelphia, Pennsylvania, United States, 19104-3309 United States, Washington Pfizer Investigational Site Kirkland, Washington, United States, 98033 Pfizer Investigational Site Kirkland, Washington, United States, 98034 Collapse << |
| NCT00748566 | Schizophrenia and Disorders Wi... more >>th Psychotic Features Collapse << | Phase 4 | Terminated(See Detailed Descri... more >>ption) Collapse << | - | Canada, Alberta ... more >> Pfizer Investigational Site Calgary, Alberta, Canada, T2N 2T9 Pfizer Investigational Site Calgary, Alberta, Canada, T2N 4Z6 Pfizer Investigational Site Medicine Hat, Alberta, Canada, T1A 4C2 Pfizer Investigational Site Medicine Hat, Alberta, Canada, T1B 4E7 Pfizer Investigational Site Red Deer, Alberta, Canada, T4N 1T6 Canada, British Columbia Pfizer Investigational Site Penticton, British Columbia, Canada, V2A 4M4 Pfizer Investigational Site Victoria, British Columbia, Canada, V8R 4Z3 Canada, Manitoba Pfizer Investigational Site Winnipeg, Manitoba, Canada, R3A 1R9 Pfizer Investigational Site Winnipeg, Manitoba, Canada, R3E 3N4 Pfizer Investigational Site Winnipeg, Manitoba, Canada, R3K 2E2 Pfizer Investigational Site Winnipeg, Manitoba, Canada, R3P 0N5 Canada, New Brunswick Pfizer Investigational Site Bathurst, New Brunswick, Canada, E2A 2Z6 Canada, Newfoundland and Labrador Pfizer Investigational Site St. John's, Newfoundland and Labrador, Canada, A1E 4J8 Canada, Nova Scotia Pfizer Investigational Site Halifax, Nova Scotia, Canada, B3H 2E2 Pfizer Investigational Site Sydney, Nova Scotia, Canada, B1P 1C6 Pfizer Investigational Site Sydney, Nova Scotia, Canada, B1P 1E1 Canada, Ontario Pfizer Investigational Site Burlington, Ontario, Canada, L7R 4E2 Pfizer Investigational Site Chatham, Ontario, Canada, N7L 1B7 Pfizer Investigational Site Kingston, Ontario, Canada, K7L 4X3 Pfizer Investigational Site London, Ontario, Canada, N6A 4G5 Pfizer Investigational Site Markham, Ontario, Canada, L6B 1A1 Pfizer Investigational Site Mississauga, Ontario, Canada, L5M 4N4 Pfizer Investigational Site Ottawa, Ontario, Canada, K1H 8K7 Pfizer Investigational Site Sudbury, Ontario, Canada, P3E 1X3 Pfizer Investigational Site Toronto, Ontario, Canada, M5T 1R8 Pfizer Investigational Site Toronto, Ontario, Canada, M6J 1H4 Pfizer Investigational Site Windsor, Ontario, Canada, N9C 3Z4 Canada, Quebec Pfizer Investigational Site Montreal, Quebec, Canada, H1N 3M5 Pfizer Investigational Site Montreal, Quebec, Canada, H1N 3V2 Pfizer Investigational Site Montreal, Quebec, Canada, H3A 1A1 Pfizer Investigational Site Verdun, Quebec, Canada, H4H 1R3 Canada, Saskatchewan Pfizer Investigational Site Saskatoon, Saskatchewan, Canada, S7K 3H3 Collapse << |
| NCT00374543 | - | - | Terminated(Recruitment goal co... more >>uld not be achieved) Collapse << | - | - |
| NCT01053429 | - | - | Completed | - | - |
| NCT00649064 | Schizoaffective Disorder ... more >> Schizophrenia Collapse << | Phase 4 | Completed | - | Taiwan ... more >> Pfizer Investigational Site Changhua, Taiwan Pfizer Investigational Site Tainan, Taiwan Pfizer Investigational Site Taipei, Taiwan Collapse << |
| NCT00538642 | Schizophrenia ... more >> Schizoaffective Disorder Bipolar Disorder Collapse << | Not Applicable | Completed | - | United States, Texas ... more >> The University of Texas Health Science Center At San Antonio San Antonio, Texas, United States, 78229 Collapse << |
| NCT01006551 | Schizophrenia | Phase 2 | Completed | - | United States, Massachusetts ... more >> Harvard University Medford, Massachusetts, United States, 02155 United States, North Carolina University of North Carolina, Chapel Hill Chapel Hill, North Carolina, United States, 27599 United States, Ohio Case Western Reserve University Cleveland, Ohio, United States, 44106 United States, Washington University of Washington Seattle, Washington, United States, 98125 Collapse << |
| NCT01053429 | - | - | Completed | - | - |
| NCT00579670 | - | - | Completed | - | Greece ... more >> Pfizer Investigational Site Athens, Greece, 12461 Pfizer Investigational Site Chaidari, Greece, 124 61 Pfizer Investigational Site Chaidari, Greece, 12461 Pfizer Investigational Site Chaidari, Greece, 12462 Pfizer Investigational Site Corfu, Greece, 49100 Pfizer Investigational Site Crete, Greece, 731-00 Pfizer Investigational Site Giannitsa, Greece, 58100 Pfizer Investigational Site Haidari, Greece, 12461 Pfizer Investigational Site Kalamata, Greece, 24100 Pfizer Investigational Site Katerini, Greece, 60100 Pfizer Investigational Site Kozani, Greece, 50100 Pfizer Investigational Site Kozani, Greece Pfizer Investigational Site Lamia, Greece, 35100 Pfizer Investigational Site Larisa, Greece Pfizer Investigational Site Patra, Greece, 26000 Pfizer Investigational Site Patra, Greece, 26001 Pfizer Investigational Site Thessaloniki, Greece, 564-29 Pfizer Investigational Site Thessaloniki, Greece, 56430 Pfizer Investigational Site Thessaloniki, Greece, 57010 Pfizer Investigational Site Volos, Greece, 38222 Collapse << |
| NCT00403546 | Schizophrenia | Phase 3 | Completed | - | United States, Georgia ... more >> Medical College of Georgia Augusta, Georgia, United States, 30912 United States, Massachusetts Corrigan Mental Health Center Fall River, Massachusetts, United States, 02720 United States, Michigan Touchstone innovare Grand Rapids, Michigan, United States, 49503 United States, New Mexico University of New Mexico Albuquerque, New Mexico, United States, 87131 United States, New York SUNY Downstate Medical Center Brooklyn, New York, United States, 11203 The Lieber Center for Schizophrenia Research - Columbia University New York, New York, United States, 10032 Nathan Kline Institute Orangeburg, New York, United States, 10962 United States, North Carolina Duke University - John Umstead Hospital Butner, North Carolina, United States, 27509 United States, Texas The Mech Center Plano, Texas, United States, 75024 Collapse << |
| NCT00579670 | - | - | Completed | - | - |
| NCT00538642 | - | - | Completed | - | - |
| NCT01293825 | Medication Adherence ... more >> Bipolar Disorder Collapse << | Phase 4 | Completed | - | United States, Ohio ... more >> University Hospitals Case Medical Center Cleveland, Ohio, United States, 44106 Collapse << |
| NCT00237666 | Bipolar II Disorder ... more >> Major Depressive Episode Collapse << | Phase 4 | Completed | - | United States, New York ... more >> Medical Research Network, L.L.C. New York, New York, United States, 10024 United States, Texas The Mech Center Plano, Texas, United States, 75024 Collapse << |
| NCT00748566 | - | - | Terminated(See Detailed Descri... more >>ption) Collapse << | - | - |
| NCT03768726 | Bipolar Disorder | Phase 3 | Not yet recruiting | September 7, 2020 | - |
| NCT00403546 | - | - | Completed | - | - |
| NCT00395031 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 2 Phase 3 | Completed | - | United States, New York ... more >> Manhattan Psychiatric Center New York, New York, United States, 10035 Collapse << |
| NCT00237666 | - | - | Completed | - | - |
| NCT00622739 | Bipolar Disorder | Phase 4 | Completed | - | United States, Texas ... more >> UT Southwestern Medical Center Dallas, Texas, United States, 75390 Collapse << |
| NCT01293825 | - | - | Completed | - | - |
| NCT00835107 | Depression, Bipolar | Phase 4 | Completed | - | Canada, Ontario ... more >> Providence Care Mental Health Services Kingston, Ontario, Canada, K7L 4X3 Collapse << |
| NCT01113541 | Bipolar Disorder | Phase 3 | Terminated(See termination rea... more >>son in detailed description.) Collapse << | - | Canada, Alberta ... more >> Foothills Medical Centre, Department of Psychiatry Calgary, Alberta, Canada, T2N 2T9 Mental Health Centre for Research and Education Calgary, Alberta, Canada, T2N 2T9 Canada, British Columbia Dr. Alexander McIntyre Inc. Penticton, British Columbia, Canada, V2A 4M4 Canada, Manitoba Country Club Plaza Winnipeg, Manitoba, Canada, R3K 2E2 Edgeland Medical, Dr. Alla Kirshner Medical Corporation Winnipeg, Manitoba, Canada, R3P 0N5 Canada, Nova Scotia Capital, Health Authority, QE II Health Sciences Centre, Mood Disorder Clinic Halifax, Nova Scotia, Canada, B3H 2E2 Office of Dr. A. K. Munshi Sydney, Nova Scotia, Canada, B1S 2E8 Canada, Quebec Centre de recherche Fernand-Seguin de l'hopital Louis H. Lafontaine Montreal, Quebec, Canada, H1N 3V2 Clinique St-Leonard Montreal, Quebec, Canada, H1P 3K2 Diex Research Sherbrooke Inc. Sherbrooke, Quebec, Canada, J1H 1Z1 Collapse << |
| NCT01113541 | - | - | Terminated(See termination rea... more >>son in detailed description.) Collapse << | - | - |
| NCT01198353 | Schizophrenia ... more >> Schizoaffective Disorder Collapse << | Phase 4 | Completed | - | Korea, Republic of ... more >> Korea University Medical Center Ansan Hospital Ansan, Gyeonggi-do, Korea, Republic of, 425-707 Soonchunhyang University Bucheon Hospital Bucheon, Korea, Republic of, 420-767 Inha University Hospital Incheon, Korea, Republic of, 400-700 Catholic University Our Lady of Mercy Hospital Incheon, Korea, Republic of, 403-720 Korea University Medical Center Guro Hospital Seoul, Korea, Republic of, 152-703 Kangnam Sacred Heart Hospital Seoul, Korea, Republic of, 431-070 Collapse << |
| NCT00555997 | - | - | Completed | - | - |
| NCT00555997 | Major Depressive Disorder | Phase 2 | Completed | - | United States, California ... more >> Cedars-Sinai Medical Center Los Angeles, California, United States, 90048 United States, Connecticut University of Connecticut Health Center Farmington, Connecticut, United States, 06030-6415 Comprehensive Psychiatric Care Norwich, Connecticut, United States, 06360 United States, Illinois Psychiatric Medicine Associates, L.L.C. Chicago, Illinois, United States, 60612 United States, Massachusetts Massachusetts General Hosptial Boston, Massachusetts, United States, 02114 Cambridge Health Alliance Cambridge, Massachusetts, United States, 02139 United States, Tennessee Vanderbilt University Medical Center Nashville, Tennessee, United States, 37212 Collapse << |
| NCT01581866 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> SFBC Ft. Myers, Inc. Fort Myers, Florida, United States, 33901 Collapse << |
| NCT02935998 | Schizophrenia | Phase 4 | Unknown | December 2017 | China, Beijing ... more >> Beijing Huilongguan Hospital Not yet recruiting Beijing, Beijing, China, 100096 Contact: Yang Fude, Director +8613651336121 yangfd200@126.com Contact: Zhang Qi, Residents +8613051296767 407291579@qq.com Collapse << |
| NCT01581879 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> SFBC Ft. Myers, Inc. Fort Myers, Florida, United States, 33901 Collapse << |
| NCT01714011 | Schizophrenia | Phase 4 | Completed | - | Malaysia ... more >> University Malaya Medical Centre Kuala Lumpur, Malaysia, 59100 Collapse << |
| NCT00622739 | - | - | Completed | - | - |
| NCT01053429 | - | - | Completed | - | - |
| NCT01053429 | - | - | Completed | - | - |
