CAS No.: 193000-39-4
ZM323881 HCl Catalog No. CSN18068
Synonyms: ZM 323881 (hydrochloride);ZM-323881;ZM323881 HCl
ZZZM 323881 HCl is a potent and selective VEGFR2 inhibitor with IC50 of < 2 nM, almost no activity on VEGFR1, PDGFRβ, FGFR1, EGFR and ErbB2.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 参考文献
- [1] Endo A, Fukuhara S, et al. Selective inhibition of vascular endothelial growth factor receptor-2 (VEGFR-2) identifies a central role for VEGFR-2 in human aortic endothelial cell responses to VEGF. J Recept Signal Transduct Res. 2003;23(2-3):239-54.
- [2] Whittles CE, Pocock TM, et al. ZM323881, a novel inhibitor of vascular endothelial growth factor-receptor-2 tyrosine kinase activity. Microcirculation. 2002 Dec;9(6):513-22.
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 193000-39-4 | 储存条件 |
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| 分子式 | C22H19ClFN3O2 | 运输 | 蓝冰 | |
| 分子量 | 411.86 | 别名 | ZM 323881 (hydrochloride);ZM-323881;ZM323881 HCl |
