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CAS No.: 1620458-09-4
Synonyms: ETX0914;AZD0914;CAS#1620458-09-4
Zoliflodacin (ETX0914;AZD0914) is a novel spiropyrimidinetrione bacterial DNA gyrase/topoisomerase inhibitor. Zoliflodacin has potent in vitro antibacterial activity against Gram-positive and Gram-negative organisms, including S. aureus with the MIC90 of 0.25 μg/mL.
生物活性
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|---|---|---|---|---|
NCT01929629 | Gonococcal (GC) Infection | Phase 1 | Completed | - | United States, Kansas ... more >> Research Site Overland Park, Kansas, United States Collapse << |
NCT02298920 | Healthy | Phase 1 | Completed | - | United States, Wisconsin ... more >> Covance Clinical Research Unit Madison, Wisconsin, United States, 53704 Research Site Madison, Wisconsin, United States Collapse << |
NCT02257918 | Gonorrhoea | Phase 2 | Completed | - | United States, Alabama ... more >> Jefferson County Department of Health - STD Clinic Birmingham, Alabama, United States, 35233-1502 United States, Indiana Indiana University - Bell Flower Clinic Indianapolis, Indiana, United States, 46202-5112 United States, Louisiana CrescentCare Health and Wellness Center New Orleans, Louisiana, United States, 70119 United States, North Carolina Durham County Health Department Durham, North Carolina, United States, 27701-3720 United States, Washington Public Health STD Clinic Seattle, Washington, United States, 98104 Collapse << |
实验方案
技术信息
CAS号 | 1620458-09-4 | 储存条件 |
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分子式 | C22H22FN5O7 | 运输 | 蓝冰 | |
分子量 | 487.44 | 别名 | ETX0914;AZD0914;CAS#1620458-09-4 |
NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
---|
NCT01929629 | Gonococcal (GC) Infection | Phase 1 | Completed | - | United States, Kansas ... more >> Research Site Overland Park, Kansas, United States Collapse << |
NCT02298920 | Healthy | Phase 1 | Completed | - | United States, Wisconsin ... more >> Covance Clinical Research Unit Madison, Wisconsin, United States, 53704 Research Site Madison, Wisconsin, United States Collapse << |
NCT02257918 | Gonorrhoea | Phase 2 | Completed | - | United States, Alabama ... more >> Jefferson County Department of Health - STD Clinic Birmingham, Alabama, United States, 35233-1502 United States, Indiana Indiana University - Bell Flower Clinic Indianapolis, Indiana, United States, 46202-5112 United States, Louisiana CrescentCare Health and Wellness Center New Orleans, Louisiana, United States, 70119 United States, North Carolina Durham County Health Department Durham, North Carolina, United States, 27701-3720 United States, Washington Public Health STD Clinic Seattle, Washington, United States, 98104 Collapse << |
NCT03613649 | Electrocardiogram Repolarisati... more >>on Abnormality Gonococcal Infection Collapse << | Phase 1 | Active, not recruiting | January 6, 2019 | United States, Kansas ... more >> Vince and Associates Clinical Research Overland Park, Kansas, United States, 66212 Collapse << |
NCT02257918 | - | - | Completed | - | - |
NCT03718806 | Gonorrhea | Phase 1 | Completed | - | United States, Florida ... more >> Quotient Sciences Miami, Florida, United States, 33126 Collapse << |
NCT03404167 | Gonorrhoea | Phase 1 | Completed | - | United States, Kansas ... more >> Quintiles Phase I Services - Overland Park Overland Park, Kansas, United States, 66211-1553 Collapse << |
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