CAS No.: 68291-97-4
Zonisamide/唑尼沙胺 Catalog No. CSN18679
Synonyms: AD 810;CI 912;Exceglan
Zonisamide, a 1,2 benzisoxazole derivative, is developed as an antiepileptic drug.
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纯度 & 质量文件
批次:
靶点选择性
生物活性
- 描述
- 临床研究
NCT号 适应症或疾病 临床期 招募状态 预计完成时间 地点 NCT02220803 Obstructive Sleep Apnea ... more >> Sleep-Disordered Breathing Blood Pressure Hypertension Collapse << Phase 2 Completed - Sweden ... more >> Center for Sleep and Vigilance disorders Gothenburg, Vastra Gotaland, Sweden, 40530 Collapse << NCT01713946 Tuberous Sclerosis Complex-ass... more >>ociated Refractory Seizures Collapse << Phase 3 Completed - - NCT02707965 Epilepsy Phase 4 Completed - United States, Maryland ... more >> University of Maryland, Baltimore Baltimore, Maryland, United States, 21201 Collapse << - 更多
- 参考文献
- [1] Sonsalla PK, Wong LY, et al. The antiepileptic drug zonisamide inhibits MAO-B and attenuates MPTP toxicity in mice: clinical relevance. Exp Neurol. 2010 Feb;221(2):329-34.
- [2] Tanabe M, Sakaue A, et al. Centrally mediated antihyperalgesic and antiallodynic effects of zonisamide following partial nerve injury in the mouse. Naunyn Schmiedebergs Arch Pharmacol. 2005 Aug;372(2):107-14.
- [3] Peters DH, Sorkin EM. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs. 1993;45(5):760‐787
- [4] Buoli M, Grassi S, Ciappolino V, Serati M, Altamura AC. The Use of Zonisamide for the Treatment of Psychiatric Disorders: A Systematic Review. Clin Neuropharmacol. 2017;40(2):85‐92
- [5] Matsunaga S, Kishi T, Iwata N. Combination Therapy with Zonisamide and Antiparkinson Drugs for Parkinson's Disease: A Meta-Analysis. J Alzheimers Dis. 2017;56(4):1229‐1239
- [6] Hossain MM, Weig B, Reuhl K, Gearing M, Wu LJ, Richardson JR. The anti-parkinsonian drug zonisamide reduces neuroinflammation: Role of microglial Nav 1.6. Exp Neurol. 2018;308:111‐119
- [7] Murata M, Odawara T, Hasegawa K, et al. Adjunct zonisamide to levodopa for DLB parkinsonism: A randomized double-blind phase 2 study. Neurology. 2018;90(8):e664‐e672
实验方案
- 计算器
- 储存液制备
技术信息
| CAS号 | 68291-97-4 | 储存条件 |
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| 分子式 | C8H8N2O3S | 运输 | 蓝冰 | |||||
| 分子量 | 212.23 | 别名 | AD 810;CI 912;Exceglan;Excegram;PD-110843;唑尼沙胺 | |||||
| 溶解度 |
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动物实验配方 |
| NCT号 | 适应症或疾病 | 临床期 | 招募状态 | 预计完成时间 | 地点 |
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| NCT02220803 | Obstructive Sleep Apnea ... more >> Sleep-Disordered Breathing Blood Pressure Hypertension Collapse << | Phase 2 | Completed | - | Sweden ... more >> Center for Sleep and Vigilance disorders Gothenburg, Vastra Gotaland, Sweden, 40530 Collapse << |
| NCT01713946 | Tuberous Sclerosis Complex-ass... more >>ociated Refractory Seizures Collapse << | Phase 3 | Completed | - | - |
| NCT02707965 | Epilepsy | Phase 4 | Completed | - | United States, Maryland ... more >> University of Maryland, Baltimore Baltimore, Maryland, United States, 21201 Collapse << |
| NCT00552526 | Epilepsy Ment... more >>al Retardation Collapse << | Phase 4 | Unknown | December 2013 | Norway ... more >> SSE, Nevrological dep. , Rikshospitalet University hospital Oslo, Norway Collapse << |
| NCT01713946 | - | - | Completed | - | - |
| NCT00404248 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 1 Phase 2 | Completed | - | United States, Alabama ... more >> UAB Comprehensive Cancer Center Birmingham, Alabama, United States, 35294-3410 United States, Florida H. Lee Moffitt Cancer Center and Research Institute at University of South Florida Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231 United States, Massachusetts Massachusetts General Hospital Boston, Massachusetts, United States, 02114 United States, Michigan Josephine Ford Cancer Center at Henry Ford Hospital Detroit, Michigan, United States, 48202 United States, North Carolina Wake Forest University Comprehensive Cancer Center Winston-Salem, North Carolina, United States, 27157-1096 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Collapse << |
| NCT00068770 | Brain and Central Nervous Syst... more >>em Tumors Collapse << | Phase 2 | Terminated(EORTC trail showed ... more >>TMZ & RT conferred significant survivial in this population) Collapse << | - | United States, Florida ... more >> H. Lee Moffitt Cancer Center and Research Institute Tampa, Florida, United States, 33612-9497 United States, Georgia Winship Cancer Institute of Emory University Atlanta, Georgia, United States, 30322 United States, Maryland Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Baltimore, Maryland, United States, 21231-2410 United States, Massachusetts Massachusetts General Hospital Cancer Center Boston, Massachusetts, United States, 02114-2617 United States, North Carolina Comprehensive Cancer Center at Wake Forest University Winston-Salem, North Carolina, United States, 27157-1030 United States, Ohio Cleveland Clinic Taussig Cancer Center Cleveland, Ohio, United States, 44195 United States, Pennsylvania Abramson Cancer Center of the University of Pennsylvania Philadelphia, Pennsylvania, United States, 19104-4283 Collapse << |
| NCT02205931 | Epilepsy | Phase 4 | Recruiting | June 2019 | United Kingdom ... more >> Birmingham Children's Hospital Recruiting Birmingham, United Kingdom, B4 6NH Contact: Shakti Agrawal, MBBS 0044 1213338149 shakti.agrawal@bch.nhs.uk Principal Investigator: Shakti Agrawal, MBBS Bristol Royal Hospital for Children Recruiting Bristol, United Kingdom, BS2 8AE Contact: Andrew Mallick, FRCPCH Principal Investigator: Andrew Mallick Addenbrooke's Hospital Recruiting Cambridge, United Kingdom, CB2 0QQ Contact: Alasdair Parker, MA 0044 1223 245151 alasdair.parker@addenbrookes.nhs.uk Principal Investigator: Alasdair Parker, MA Lancashire Teaching Hospitals NHS Foundation Trust Recruiting Lancashire, United Kingdom Contact: Helen Basu Helen.Basu@lthtr.nhs.uk Principal Investigator: Helen Basu Leeds Teaching Hospital Recruiting Leeds, United Kingdom, LS1 3EX Contact: Helen McCullagh, RCPCH 0044 113 243 2799 h.mccullagh@nhs.net Principal Investigator: Helen McCullagh, RCPCH Alder Hey Children's Hospital Recruiting Liverpool, United Kingdom, L12 2AP Contact: Rachel Kneen, BMBS 0044 151 2525163 rachel.kneen@liverpool.ac.uk Principal Investigator: Rachel Kneen, BMBS Great Ormond Street Hospital Recruiting London, United Kingdom, WC1N 3JH Contact: Christin Eltze, MD Res 0044 207 405 9200 ext 5438 christin.eltze@gosh.nhs.uk Principal Investigator: Christin Eltze, MD Res St George's University Hospitals NHS Foundation Trust Recruiting London, United Kingdom Contact: Penny Fallon Penny.Fallon@stgeorges.nhs.uk Principal Investigator: Penny Fallon Royal Manchester Children's Hospital Recruiting Manchester, United Kingdom, M13 0JE Contact: Tim Martland, RCPCH 0044 161 276 1234 timothy.martland@cmft.nhs.uk Principal Investigator: Tim Martland, RCPCH The Newcastle Upon Tyne Hospitals NHS Foundation Trust Recruiting Newcastle upon Tyne, United Kingdom Contact: Anita Devlin Anita.Devlin@nuth.nhs.uk Principal Investigator: Anita Devlin Sheffield Children's NHS Foundation Trust Recruiting Sheffield, United Kingdom Contact: Archana Desurkar Archana.Desurkar@sch.nhs.uk Principal Investigator: Archana Desurkar Collapse << |
| NCT00068770 | - | - | Terminated(EORTC trail showed ... more >>TMZ & RT conferred significant survivial in this population) Collapse << | - | - |
| NCT03636958 | Refractory Epilepsy | Not Applicable | Not yet recruiting | December 2022 | France ... more >> Assistance Publique Des Hopitaux de Marseille Not yet recruiting Marseille, Paca, France, 13354 Contact: STANISLAS LAGARDE, MD +33 491385554 Stanislas.LAGARDE@ap-hm.fr Collapse << |
| NCT00566254 | - | - | Completed | - | - |
| NCT02727101 | Epilepsy | Phase 4 | Terminated(slow enrollment) | - | United States, Maryland ... more >> MidAtlantic Epilepsy and Sleep Center Bethesda, Maryland, United States, 20817 Collapse << |
| NCT01549288 | Infantile Spasms | Phase 2 Phase 3 | Withdrawn | December 2013 | India ... more >> Lady Hardinge Medical College and Associated Kalawati Saran Children's Hospital New Delhi, Delhi, India, 110001 Collapse << |
| NCT00759993 | Weight Gain O... more >>besity Collapse << | Phase 2 | Terminated(inability to recrui... more >>t and retain) Collapse << | March 2013 | - |
| NCT01390909 | - | - | Completed | - | - |
| NCT00404248 | - | - | Completed | - | - |
| NCT03689114 | Epilepsies, Partial | Phase 4 | Not yet recruiting | December 2021 | - |
| NCT01587339 | - | - | Completed | - | - |
| NCT01390909 | - | - | Completed | - | - |
| NCT00777218 | Migraine | Not Applicable | Unknown | July 2011 | United States, Alabama ... more >> University of South Alabama Department of Neurology Recruiting Mobile, Alabama, United States, 36693 Sub-Investigator: Maher Loutfi, MD Collapse << |
| NCT00855738 | Focal Epilepsy | Phase 4 | Completed | - | - |
| NCT00298818 | - | - | Completed | - | United States, New York ... more >> Long Island Jewish Medical Center New Hyde Park, New York, United States, 11040 Collapse << |
| NCT00855738 | - | - | Completed | - | - |
| NCT00401973 | Schizophrenia ... more >> Schizoaffective Disorders Collapse << | Phase 3 | Completed | - | United States, California ... more >> For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. National City, California, United States, 91950 United States, Ohio For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Canton, Ohio, United States, 44708 United States, Tennessee For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Johnson City, Tennessee, United States, 37614 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Memphis, Tennessee, United States, 38105 United States, Texas For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Desoto, Texas, United States, 75115 Brazil For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Rio De Janeiro, Brazil, 21020-130 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Salvador, Brazil, 40301500 Israel For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Beer Yaacov, Israel, 70350 Korea, Republic of For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Seoul, Korea, Republic of, 143-711 Mexico For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Mexico City, Mexico, 14050 Puerto Rico For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Bayamon, Puerto Rico, 00961 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Ponce, Puerto Rico, 00717 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. San Juan, Puerto Rico, 00907 For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. San Juan, Puerto Rico Russian Federation For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician. Moscow, Russian Federation, 117603 Collapse << |
| NCT00401973 | - | - | Completed | - | - |
| NCT00154076 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... more >> Daegu Catholic University Medical Center Daegu, Korea, Republic of Collapse << |
| NCT00215592 | Epilepsy | Phase 4 | Completed | - | Austria ... more >> Universitatsklinikum fur Neurologie Innsbruck, Austria, 6020 Denmark Danish Epilepsy Center Dianalund, Denmark, 4293 The Epilepsy Clinic Glostrup, Denmark, 2600 France Centre Hospitalier d'Annecy Annecy cedex, France, 74011 CH Germon et Gauthier Bethune, France, 62408 Hopital Pellegrin Tripode Bordeaux cedex, France, 33076 Hopital Gabriel Montpied Clermont-Ferrand Cedex 1, France, 63003 Hopital General Dijon, France, 21033 Hopital Victor Jousselin Dreux, France, 28102 Cabinet de neurologie Gap, France, 05000 Hopital de la Timone Adultes Marseille, France, 13385 Groupe hospitalier Pitie Salpetriere Paris, France, 75651 Hopital de Font Pre Toulon cedex, France, 83056 CHU Bretonneau Tours Cedex, France, 37044 Germany Universitatsklinikum Campus Virchow-Klinikum Wedding Berlin, Germany, 13353 Epilepsieklinik Tabor Bernau b. Berlin, Germany, 16321 Universitat Freiburg Freiburg, Germany, 79106 Epilepsiezentrum Kork Kehl-Kork, Germany, 77694 Arzneimittelforschung Leipzig GmbH Leipzig, Germany, 04107 Klinik die Weissenau Revensburg, Germany, 88214 Italy Ospedale Riuniti di Bergamo Bergamo, Italy, 24128 Azienda Ospedaliero- Universitaria Policlinico di Catania Catania, Italy, 95125 Istituto Nazionale Neurologico Carlo Besta di Milano Milano, Italy, 20133 Azienda Ospedaliera San Paolo Milano, Italy, 20142 Universita di Parma Parma, Italy, 43100 Azienda Ospedaliera Bianchi-Melancrino-Morelli Reggio Calabria, Italy, 89100 Universita degli studi La Sapienza Roma, Italy, 00161 Universita degli Studi La Sapienza Roma, Italy, 00185 Norway Nevrologisk avdelning, 10 etasje Lillehammer, Norway, 2609 Sandvika Neurologpraksis Sandvika, Norway, 1338 Avd. for nevrologi og klinisk nevrofysiologi Trondheim, Norway, 7006 United Kingdom University Hospital of Wales Cardiff, United Kingdom, CF14 4XW University Hospital of North Staffordshire Royal Infirmary Stoke On Trent, United Kingdom, ST4 7LN Collapse << |
| NCT00862563 | Alcoholism Al... more >>cohol Dependence Alcohol Abuse Collapse << | Phase 2 | Terminated(Recruitment goals c... more >>ould not be met before ending of funding for this project.) Collapse << | - | United States, Massachusetts ... more >> Boston University School of Medicine Boston, Massachusetts, United States, 02118 Collapse << |
| NCT00056576 | Epilepsy, Complex Partial | Phase 3 | Completed | - | - |
| NCT02901041 | Alcohol Dependence | Phase 3 | Recruiting | August 2021 | United States, Massachusetts ... more >> Center for Anxiety and Related Disorders - Boston University Recruiting Boston, Massachusetts, United States, 02115 Contact: David H Barlow, PhD 627-353-9610 Collapse << |
| NCT01127256 | - | - | Completed | - | - |
| NCT00292461 | Epilepsy | Phase 3 | Completed | - | China, Taiwan ... more >> Changhua Christian Hospital Changhua, Taiwan, China Chang-Gung Memorial Hospital (CGMH) Kaohsiung, Taiwan, China Chang-Gung Memorial Hospital (CGMH) Linkou, Taiwan, China China Medical University Hospital (CMUH) Taichun, Taiwan, China National Cheng Kung University Hospital Tainan, Taiwan, China Chang-Gung Memorial Hospital (CGMH) Taipei, Taiwan, China Taipei Tzu Chi General Hospital Taipei, Taiwan, China Taipei Veterans General Hospital Taipei, Taiwan, China Collapse << |
| NCT01127256 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... more >> Seoul National Univ. Bundang Hosp. Bundang, Korea, Republic of Chungnam National Univ. Hosp. Chungnam, Korea, Republic of Dongguk Univ. Ilsan Hosp. Ilsan, Korea, Republic of Inha Univ. Hosp. Incheon, Korea, Republic of Boramae Medical Center Seoul, Korea, Republic of Eulji General Hosp. Seoul, Korea, Republic of Ewha Womans Univ. Mokdong Hospital Seoul, Korea, Republic of Hallym Univ. Medical Center Seoul, Korea, Republic of Hanyang Univ. Medical Center Seoul, Korea, Republic of Konkuk Univ. Medical Center Seoul, Korea, Republic of Samsung Medical Center Seoul, Korea, Republic of Seoul National Univ. Hosp. Seoul, Korea, Republic of Collapse << |
| NCT00862563 | - | - | Terminated(Recruitment goals c... more >>ould not be met before ending of funding for this project.) Collapse << | - | - |
| NCT00165828 | Epilepsy | Phase 4 | Terminated | - | Germany ... more >> Epilepsieklinik Tabor Bernau, Brandenburg, Germany, 16321 Universtitatsklinikum Bonn Bonn, Nordrhein-Westphalen, Germany, 53105 Universtitatsklinikum Munster, Klinik und Poliklinik fur Neurologie Munster, Nordrhein-Westphalen, Germany, 48129 Epilepsiezentrum Bethel/KSE Beilefeld, Germany, 33617 Institut fur Diagnostik der Epilepsien Gmbh Berlin, Germany, 10362 Charite Campus Virchow-Klinikum, Neurologische Klinik und Poliklinik Berlin, Germany, 13353 St. Josephs Hospital, Neurologische Klinik Bochum, Germany, 44791 Dr. Gunther Schumann Bochum, Germany, 44805 Knappschaftskrankenhaus Bochum-Langendreer, Neurologische Klinik Bochum, Germany, 44892 Dr. Hans Martin Kolbinger Bonn, Germany, 53127 Neuro-Consil Gmbh Dusseldorf, Germany, 40212 Neurologische Klinik der Universitat Erlangen Erlangen, Germany, 91054 Universitatsklinik Essen, Klinik und Poliklinik fur Neurologie Essen, Germany, 45147 Universitatsklinikum Freiburg, Neurozentrum Freiburg, Germany, 79106 Universitatsklinikum Gottingen, Abt. fur klinische Neurophysiologie Gottingen, Germany, 37075 Gemeinschaftpraxis fur Neurologie und Psychiatrie Hamburg, Germany, 22083 Dr. Heinrich C. Braeuer Hamburg, Germany, 22299 Ev. Krankenhaus Alsterdorf, Epilepsiezentrum Alsterdorf Hamburg, Germany, 22337 Epilepsiezentrum Kork Kehl, Germany, 77694 Epilepsiezentrum Kleinwachau, Epilepsieambulanz Liegau-Augustusbad, Germany, 01465 Universitatsklinikum Mannheim, Neurologische Klinik, Ambulanz fur Anfallserkrankte Mannheim, Germany, 68167 Universitatsklinikum, Interdisziplinares Epilepsiezentrum Marburg, Germany, 35043 Klinikum Grosshadern, Neurologische Klinik und Poliklinik, Epilepsie-Ambulanz Munchen, Germany, 81377 Klinikum Offenbach, Neurologie Offenbach, Germany, 63069 Klinik Ernst von Bergmann Potsdam, Germany, 14467 Universitat Regensburg, Klinik un Poliklinik fur Neurologie Regensburg, Germany, 93053 Klinik "Die Weissenau", Anfallsambulanz Revensburg, Germany, 88214 Universitat Rostock, Klinik fur Neurologie und Poliklinik Rostock, Germany, 18147 Universitatsklinik Ulm Poliklinik fur Neurologie, Epilepsieambulanz Ulm, Germany, 89075 Dr. Horst-Schmidt Klinik, Neurologie Wiesbaden, Germany, 65199 Collapse << |
| NCT00292461 | - | - | Completed | - | - |
| NCT00221442 | Binge Eating Disorder Associat... more >>ed With Obesity Collapse << | Phase 3 | Completed | - | United States, Ohio ... more >> University of Cincinnati Medical Center Cincinnati, Ohio, United States, 45267-0559 Collapse << |
| NCT00398918 | Alcoholism | Not Applicable | Completed | - | United States, Massachusetts ... more >> Boston University Medical Campus Boston, Massachusetts, United States, 02118 Collapse << |
| NCT00055484 | Migraine Headache | Phase 2 | Completed | - | United States, Alabama ... more >> Medical Affiliated Research Center Huntsville, Alabama, United States, 35801 University of South Alabama Medical Ctr Department of Neurology Mobile, Alabama, United States, 36693 United States, Arizona Valley Neurological Headache Clinic Phoenix, Arizona, United States, 85020 United States, Connecticut The New England Center for Headache Stamford, Connecticut, United States, 06902 United States, Kansas Radiant Research Overland Park, Kansas, United States, 66215 United States, Michigan Michigan Head-Pain & Neurological Institute Ann Arbor, Michigan, United States, 48104 United States, Missouri Mercy Health Research Chesterfield, Missouri, United States, 63017 Headache Care Center Springfield, Missouri, United States, 65804 United States, Oklahoma Neurological Associates of Tulsa Tulsa, Oklahoma, United States, 74136 United States, Pennsylvania Thomas Jefferson University Hospital Philadelphia, Pennsylvania, United States, 19107 United States, Texas MetaClin Research Austin, Texas, United States, 19107 Houston Headache Clinic Houston, Texas, United States, 77004 United States, Utah Radiant Research Salt Lake City, Utah, United States, 84111 Collapse << |
| NCT00339014 | Obesity | Phase 2 | Completed | - | United States, Alabama ... more >> SelfCenter, PC Fairhope, Alabama, United States, 36532 United States, California UCLA Center for Human Nutrition Los Angeles, California, United States, 90095 Scripps Clinic Del Mar San Diego, California, United States, 92130 United States, Colorado Center for Human Nutrition University of Colorado Health Sciences Center Denver, Colorado, United States, 80220 United States, District of Columbia George Washington University Weight Management Program Washington, District of Columbia, United States, 20037 United States, Georgia CSRA Partners in Health, Inc Augusta, Georgia, United States, 30909 United States, Illinois Springfield Diabetes and Endocrine Center Springfield, Illinois, United States, 62704 United States, Louisiana Pennington Biomedical Research Center Baton Rouge, Louisiana, United States, 70808 United States, Massachusetts Nutrition and Weight Mangement Center Boston Medical Center Boston, Massachusetts, United States, 02118 United States, Nevada Center for Nutrition and Metabolic Diseases Reno, Nevada, United States, 89557 United States, New York Comprehensive Weight Control Program New York, New York, United States, 10021 United States, North Carolina Center for Nutrition and Preventive Medicine Charlotte, North Carolina, United States, 28211 United States, South Carolina MUSC Weight Mnagement Center Charleston, South Carolina, United States, 29425 United States, Texas The Cooper Institute Dallas, Texas, United States, 75230 Baylor Endocrine Center Dallas, Texas, United States, 75246 Collapse << |
| NCT00709371 | Obesity | Phase 2 | Completed | - | - |
| NCT01546688 | Epilepsy | Phase 4 | Terminated | - | Germany ... more >> Klinik und Polyklinik fur Epileptologie Bonn, Germany Georg-August-Universiat Gottingen Gottingen, Germany Asklepiosklinik Barmbek Hamburg, Germany Clinical Research Hamburg Hamburg, Germany ZNS Hamburg Hamburg, Germany Universitaet Giessen / Marburg Marburg, Germany Neurologische Siegen, Germany Hungary Semmelweis University - Neurology Dept. Budapest, Hungary, 1083 Synexus Magyarorszag Kft. Budapest, Hungary, 11036 National Institute of Neurosurgery Budapest, Hungary, 1145 County Hospital Kecskemet Keskemet, Hungary, 6000 B-A-Z County Hospital - Szuleszet-Nogyogyaszat Miskolc, Hungary, 3501 Sopron Medical SMO Sopron, Hungary, 9400 County Hospital of Tolna Szeksz?rd, Hungary, 7100 County Hospital of Zala Zalaegerszeg, Hungary, 8900 Italy S.C. Neurologia - AO "G.Brotzu" Cagliari, Italy, 00134 Dip. Di neuroscienze - Centro Epilessie - Osp. Careggi Firenze, Italy, 50134 Dipartimento di Neuroscienze - Universita Federico II Napoli, Italy, 80131 Centro Epilessia - Istituto Neurologico "Fondazione C. Mondino" Pavia, Italy, 27100 Centro per la Diagnosi e Cura dell'epilessia - Policlinico Universitario di Messina Pavia, Italy, 27100 Dip.to Scienze Neurologiche - III Clinica Neurologica Roma, Italy, 00185 Universita di Torino - Dipt. Neuroscienze Torino, Italy, 10126 Netherlands Medisch Centrum Haaglanden - Lokatie Westeinde VA Den Haag, Netherlands, 2512 Poland Specjalistyczny Zaklad Opieki Zdrowotnej 'KONSYLIUM' Kalisz, Poland, 62-800 Specjalistyczna Praktyka Lekarska Katowice, Poland, 40- 097 NZOZ Centermed Gabinety ?lnolekarskie Leszno, Poland, 64-100 Przych. Specj. I chorob Zaw. Wsi Instytut Medyc. Wsi im. W. Chodzki Lublin, Poland, 20-090 Oddzia Neurologiczny, Wojewdzki Szpital Specjalistyczny Olsztyn, Poland, 10-561 NZOZ Centrum Medyczne HCP Pozna, Poland, 61-489 Wielospecjalistyczna Lecznica 'Zycie' Warszawa, Poland, 03-464 Switzerland Clinical Investigation Unit; Inselspital Bern, Switzerland, 3010 Spitalzentrum Biel Biel, Switzerland, 2501 Epilepsie-Zentrum Zurich, Switzerland, 8008 United Kingdom Whipps Cross university Hospital London, United Kingdom, E11 1NR University Hospital of North Staffordshire Stoke-on-Trent, United Kingdom, ST4 7LN The Royal Cornwall Hospital Truro, United Kingdom, TR1 3LJ Collapse << |
| NCT00398918 | - | - | Completed | - | - |
| NCT00650052 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
| NCT00734435 | Schizophrenia ... more >> Schizoaffective Disorder Schizophreniform Disorder Collapse << | Phase 2 | Terminated(Sponsor Decision- F... more >>inancial Considerations) Collapse << | - | United States, California ... more >> Synergy Research National City, California, United States, 91950 UCI Medical Center Orange, California, United States, 92868 CNRI San Diego San Diego, California, United States, 92126 United States, Florida Florida Clincal Research Center Bradenton, Florida, United States, 34208 Florida Clinical Research Center Maitland, Florida, United States, 34208 United States, Georgia Atlanta Center for Medical Research Atlanta, Georgia, United States, 30308 United States, Illinois American Medical Research Oak Brook, Illinois, United States, 60523 United States, Indiana Larue D. Carter Hospital Indianapolis, Indiana, United States, 46222 United States, New York Brooklyn Medical Institute Brooklyn, New York, United States, 11223 Collapse << |
| NCT01546688 | - | - | Terminated | - | - |
| NCT00848549 | - | - | Completed | - | - |
| NCT00848549 | Epilepsy | Phase 3 | Completed | - | - |
| NCT00047567 | Bipolar Disorders | Phase 4 | Terminated | - | - |
| NCT03034538 | Parkinson Disease ... more >> Parkinsonism Dyskinesias Collapse << | Phase 4 | Recruiting | December 31, 2018 | United States, New Jersey ... more >> Cooper University Health System Recruiting Camden, New Jersey, United States, 08103 Contact: Andrew March, BS 856-342-2460 march-andrew@cooperhealth.edu Principal Investigator: Andrew McGarry, MD Sub-Investigator: Amy Colcher, MD Collapse << |
| NCT01806805 | Myoclonus Dystonia | Phase 3 | Completed | - | France ... more >> Pitié salpetriere hospital Paris, France, 75013 Collapse << |
| NCT00649714 | Healthy | Phase 1 | Completed | - | United States, West Virginia ... more >> Kendle International Inc. Morgantown, West Virginia, United States, 26505 Collapse << |
| NCT00713622 | Epilepsy | Phase 4 | Completed | - | Austria ... more >> Universitae Klinik fur Neurologiet Innsbruck, Austria, 6020 Finland Kuopio University Hospital Kuopio, Finland, 70211 Collapse << |
| NCT01127165 | - | - | Completed | - | - |
| NCT02049073 | Noise-induced Hearing Loss | Phase 1 Phase 2 | Withdrawn(new data makes this ... more >>trial unethical) Collapse << | - | United States, Missouri ... more >> Washington University School of Medicine Saint Louis, Missouri, United States, 63110 Collapse << |
| NCT00659958 | Epilepsy | Phase 4 | Completed | - | Spain ... more >> Complejo Hospitalario Universitario 'Juan Canalejo' Coruna, Galicia, Spain, 15006 C.H. A. Marcide Profesor Novoa Santos Ferrol, Galicia, Spain, 15405 Centro Sanitario Complexo Hospitalario "XERAL-CALDE" Lugo, Galicia, Spain, 27004 Hospital Comarcal de Monforte Lugo, Galicia, Spain, 27400 Centro Sanitario Hospital Da Costa de Burela Lugo, Galicia, Spain, 27880 Complejo Hospitalario de Ourense Ourense, Galicia, Spain, 32005 Complejo Hospitalario de Pontevedra Pontevedra, Galicia, Spain, 36071 Complejo Hospitalario Universitario Santiago de Compostela Santiago de Compostela, Galicia, Spain, 15706 Complejo Hospitalario Universitario de Vigo (CHUVI), Hospital Meixoeiro Vigo, Galicia, Spain, 36204 Hospital Povisa Vigo, Galicia, Spain, 36211 Complejo Hospitalario Universitario de Vigo (CHUVI), Hospital Xeral-Cies Vigo, Galicia, Spain, 63204 Collapse << |
| NCT01127165 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... more >> Dongsan Medical Center of Keimyung Univ. Seoul, Korea, Republic of Gangnam Severance Hospital Seoul, Korea, Republic of Inje Univ. Ilsan-Paik Hospital Seoul, Korea, Republic of Inje Univ. Sanggye-Paik Hospital Seoul, Korea, Republic of Korea Univ. Ansan Hospital Seoul, Korea, Republic of Korea Univ. Guro Hospital Seoul, Korea, Republic of National Health Insurance Corporation Ilsan Hospital Seoul, Korea, Republic of Severance Hospital Seoul, Korea, Republic of Soonchunhyang Univ. Cheonan Hospital Seoul, Korea, Republic of Soonchunhyang Univ. Hospital Seoul, Korea, Republic of Yeungnam University Medical Center Seoul, Korea, Republic of Collapse << |
| NCT01136954 | Partial Seizures | Phase 3 | Completed | - | Italy ... more >> Firenze, 50132, FI, Italy, 50132 Collapse << |
| NCT00363376 | Weight Gain | Phase 3 | Completed | - | United States, Ohio ... more >> The Lindner Center of HOPE Mason, Ohio, United States, 45040 Collapse << |
| NCT00327717 | Partial Seizures | Phase 3 | Completed | - | China, Beijing ... more >> Peking University First Hospital Beijing, Beijing, China, 100034 Peking Union Hospital Beijing, Beijing, China, 100053 Peking Union Medical College Hospital Beijing, Beijing, China, 100730 China, Chongqing The First Affiliated Hospital of Chongqing Medical University Chongqing, Chongqing, China, 400016 China, Shanghai Shanghai Changzheng Hospital Shanghai, Shanghai, China, 200003 Shanghai Hua-shan Hospital Shanghai, Shanghai, China, 200040 China, Shanxi XiÆan Xijing Hospital XiÆan, Shanxi, China, 710032 China, Sichuan Chengdu Huaxi Hospital Chengdu, Sichuan, China, 610041 Collapse << |
| NCT01830868 | - | - | Completed | - | Austria ... more >> Ried, Austria Denmark Hillerod, Denmark Germany Asperg, Germany Baesweiler, Germany Berlin, Germany Bielefeld, Germany Dortmund, Germany Eisenach, Germany Erbach, Germany Erlangen, Germany Furth, Germany Gladenbach, Germany Hamburg, Germany Hassfurt, Germany Julich, Germany Kastellaun, Germany Lage, Germany Lappersdorf, Germany Lauf, Germany Lohr am Main, Germany Malchin, Germany Monchengladbach, Germany Munchen, Germany Neuburg an der Donau, Germany Neusass, Germany Osnabruck, Germany Remscheid, Germany Saarbrucken, Germany Schorndorf, Germany Schwabisch Gmund, Germany Senftenberg, Germany Stralsund, Germany Stuttgart, Germany Ulm, Germany Velen, Germany Norway Drammen, Norway Sweden Stockholm, Sweden Collapse << |
| NCT00327717 | - | - | Completed | - | - |
| NCT00477295 | Epilepsy | Phase 3 | Completed | - | - |
| NCT00275834 | Obesity | Not Applicable | Completed | - | United States, North Carolina ... more >> Duke University Medical Centre Durham, North Carolina, United States, 27710 Collapse << |
| NCT01136954 | - | - | Completed | - | - |
| NCT00477295 | - | - | Completed | - | - |
| NCT00259636 | Fibromyalgia ... more >>Migraine Collapse << | Phase 4 | Withdrawn(Logistical problems ... more >>prevented enrollment) Collapse << | - | United States, Pennsylvania ... more >> University of Pittsburgh Pittsburgh, Pennsylvania, United States, 15206 Collapse << |
| NCT00595556 | Alcoholism Al... more >>cohol Abuse Alcohol Dependence Collapse << | Phase 4 | Completed | - | United States, Connecticut ... more >> University of Connecticut Health Center Farmington, Connecticut, United States, 06030 Collapse << |
| NCT00223743 | Essential Tremor | Phase 2 | Completed | - | United States, California ... more >> VA Greater Los Angeles Los Angeles, California, United States, 90073 Collapse << |
| NCT00275834 | - | - | Completed | - | - |
| NCT00595556 | - | - | Completed | - | - |
| NCT00566254 | Epilepsy; Paediatric Partial O... more >>nset Seizures Collapse << | Phase 3 | Completed | - | - |
| NCT00693017 | Epilepsy | Phase 3 | Terminated(Sponsor's decision) | - | - |
| NCT01140867 | - | - | Completed | - | - |
| NCT01140867 | Epilepsy | Phase 4 | Completed | - | Korea, Republic of ... more >> Dong-A University Hospital, Dept. of Neurology Busan, Korea, Republic of Inje Univ. Pusan Paik Hospital, Dept. of Neurology Busan, Korea, Republic of Keimyung Univ.Dongsan Medical Centre, Dept. of Neurology Daegu, Korea, Republic of Kyungpook Natl. Univ. Hosp., Dept. of Neurology Daegu, Korea, Republic of Yeungnam Univ. Medical Center, Dept. of Neurology Daegu, Korea, Republic of Gachon Medical School Gil Medical Centre, Dept.of Neurology Incheon, Korea, Republic of Natl. Health Insurance Corporation Ilsan Hosp., Dept. of Neurology Koyang, Korea, Republic of Bundang CHA Hospital, Dept. of Neurology Seongnam, Korea, Republic of Kangdong Sacred Heart Hosp., Dept. of Neurology Seoul, Korea, Republic of Severance Hospital, Dept. of Neurology Seoul, Korea, Republic of Collapse << |
| NCT00693017 | - | - | Terminated(Sponsor's decision) | - | - |
| NCT00406692 | Alcoholism | Phase 2 | Completed | - | United States, Massachusetts ... more >> Boston University School of Medicine Boston, Massachusetts, United States, 02118 Collapse << |
| NCT00692003 | - | - | Terminated(Sponsor's decision) | - | - |
| NCT00692003 | Epilepsy | Phase 3 | Terminated(Sponsor's decision) | - | - |
| NCT00406692 | - | - | Completed | - | - |
| NCT01137890 | - | - | Completed | - | - |
| NCT01137890 | Cocaine Dependence | Phase 1 Phase 2 | Completed | - | United States, Maryland ... more >> Behavioral Pharmacology Research Unit Baltimore, Maryland, United States, 21224 Collapse << |
| NCT00687167 | Healthy | Phase 1 | Completed | - | United States, North Dakota ... more >> PRACS Fargo, North Dakota, United States, 58104 Collapse << |
| NCT00616343 | - | - | Terminated(Principal Investiga... more >>tor left the study site on December 28, 2012.) Collapse << | - | - |
| NCT00687167 | - | - | Completed | - | - |
| NCT00685139 | Healthy | Phase 1 | Completed | - | - |
| NCT00616343 | Essential Tremor | Not Applicable | Terminated(Principal Investiga... more >>tor left the study site on December 28, 2012.) Collapse << | - | - |
| NCT00685139 | - | - | Completed | - | - |
| NCT01283256 | - | - | Completed | - | India ... more >> Hyderabad, Andhra Pradesh, India, 500016 Hyderabad, Andhra Pradesh, India, 500027 Hyderabad, Andhra Pradesh, India, 500057 Secunderabad, Andhra Pradesh, India, 500003 Secunderabad, Andhra Pradesh, India, 500015 Vijaywada, Andhra Pradesh, India Vishakapatnam, Andhra Pradesh, India Vishakhapatnam, Andhra Pradesh, India, 530002 Ahmedabad, Gujarat, India, 380009 Ahmedabad, Gujrat, India, 380015 Bangalore, Karanataka, India, 560010 Kochi, Kerela, India, 682012 Kochi, Kerela, India, 682301 Mumbai, Maharashtra, India, 400012 Mumbai, Maharashtra, India, 400049 Pune, Maharashtra, India Jaipur, Rajastan, India, 302004 Jaipur, Rajastan, India, 302015 Jaipur, Rajastan, India, 302017 Chennai, Tamilnadu, India, 500017 Chennai, Tamilnadu, India, 600006 Chennai, Tamilnadu, India, 600010 Chennai, Tamilnadu, India, 600017 Lucknow, Uttar Pradesh, India, 226003 Lucknow, Uttar Pradesh, India, 226022 Noida, Uttar Pradesh, India, 201301 New Delhi, India, 110070 Collapse << |
| NCT02900352 | Alcohol Use Disorder | Phase 1 | Recruiting | March 2021 | United States, Connecticut ... more >> UCONN Health Recruiting Farmington, Connecticut, United States, 06030 Contact: Jonathan Covault, MD jocovault@uchc.edu Contact: Michelle Slivinsky, MA 860-679-2587 slivinsky@uchc.edu West Haven Veterans Affairs Recruiting West Haven, Connecticut, United States, 06515 Contact: Albert Arias, MD 203-932-5711 ext 8155 albert.arias@yale.edu Contact: Diana Limoncelli, BA 2039325711 ext 5217 diana.limoncelli@yale.edu Collapse << |
| NCT01630057 | Partial Seizures | Phase 4 | Completed | - | Italy ... more >> AOU Ospedali riuniti Umberto I -G.M Lancisi-G.Salesi Ancona, Italy, 60126 AO Universitaria Consorziale Policlinico di Bari Bari, Italy, 70124 Irccs "E. Medea" Bosisio Parini, Italy, 23842 Struttura di Neurofisiopatologia, Universit? degli studi di Cagliari Cagliari, Italy, 09124 IRCCS "Eugenio Medea" Polo Scientifico di Conegliano Conegliano, Italy, 31015 AOU di Ferrara Arcispedale S. Anna Ferrara, Italy, 44100 Presidio Ospedale "S.Antonio Abate di Gallarate" Gallarate, Italy, 21013 UOC Neurofisiopatologia PO S. Salvatore L'Aquila, Italy, 67100 AO della Provincia di Lodi Lodi, Italy, 26900 IRCCS Centro neurolesi "Bonino Pulejo" di Messina Messina, Italy, 98124 AO di Rilievo Nazionale Antonio Cardarelli Napoli, Italy, 80131 AO Universitaria Federico II Napoli, Italy, 80131 AO Universitaria Policlinico Paolo Giaccone dell'Universit? degli Studi di Palermo Palermo, Italy, 90127 AO Universitaria -Pisana Pisa, Italy, 56126 AO Regionale "San Carlo" di Potenza Potenza, Italy, 85100 PO "Misericordia e dolce"-USL 4 di Prato Prato, Italy, 59100 Azienda Complesso Ospedaliero San Filippo Neri Roma, Italy, 00135 Umberto I Policlinico di Roma Roma, Italy, 00161 Ospedale SS Giovanni e Paolo Azienda ULSS 12 Veneziana Venezia, Italy, 30174 Collapse << |
| NCT01161966 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> SFBC Ft. Myers, Inc. Fort Myers, Florida, United States, 33901 Collapse << |
| NCT01161979 | Healthy | Phase 1 | Completed | - | United States, Florida ... more >> SFBC Ft. Myers, Inc. Fort Myers, Florida, United States, 33901 Collapse << |
| NCT01847469 | Alcohol Dependence ... more >> Post-Traumatic Stress Disorder (PTSD) Collapse << | Phase 2 | Recruiting | October 2019 | United States, Connecticut ... more >> VA Connecticut Healthcare System Recruiting West Haven, Connecticut, United States, 06516 Contact: Elizabeth Ralevski, Ph.D. 203-932-5711 ext 4282 elizabeth.ralevski@yale.edu Collapse << |
| NCT01766128 | Parkinson Disease | Phase 2 Phase 3 | Unknown | April 2014 | - |
| NCT01685996 | Nicotine Dependence | Phase 1 Phase 2 | Completed | - | United States, Maryland ... more >> Behavioral Pharmacology Research Unit Baltimore, Maryland, United States, 21224 Collapse << |
| NCT03376139 | Post Traumatic Stress Disorder... more >> Alcohol Use Disorder Collapse << | Phase 2 | Not yet recruiting | March 31, 2020 | United States, Texas ... more >> Michael E. DeBakey Veterans Affairs Medical Center Not yet recruiting Houston, Texas, United States, 77030 Collapse << |
| NCT01566370 | Alcohol Use Disorders ... more >> Bipolar Disorder Collapse << | Phase 2 | Terminated(recruitment infeasi... more >>ble) Collapse << | - | United States, Connecticut ... more >> VA Connecticut Healthcare System West Haven, Connecticut, United States, 06516 Collapse << |
| NCT01566370 | - | - | Terminated(recruitment infeasi... more >>ble) Collapse << | - | - |
| NCT00203450 | Obesity | Phase 4 | Completed | - | United States, Alabama ... more >> Tuscaloosa Research & Education Advancement Corporation Tuscaloosa, Alabama, United States, 35404 Collapse << |
| NCT01765608 | Sleep Apnea O... more >>bstructive Sleep Apnea Obesity Collapse << | Phase 2 | Completed | - | Sweden ... more >> Center for Sleep and Vigilance Disorders Gothenburg, Västra Götaland, Sweden, 40530 Collapse << |
| NCT01685996 | - | - | Completed | - | - |
| NCT02368431 | Alcohol Use Disorder | Phase 3 | Active, not recruiting | April 1, 2020 | United States, Connecticut ... more >> VA Connecticut Healthcare System West Haven Campus, West Haven, CT West Haven, Connecticut, United States, 06516 Collapse << |
