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PROTAC Linker

货号 产品名 CAS号 信息
CSN23940 (S,R,S)-AHPC-C4-NH2 HCl 2245697-83-8 VH032-ketone-C4-Amine HCl is a PROTAC block consist of VHL032 linked to alkyl with an Amine functional group for conjugation reactions.
CSN32767 tert-Butyl 3-(2-iodoethoxy)propanoate 2296723-16-3 tert-Butyl 3-(2-iodoethoxy)propanoate is a linker.
CSN32755 Hydroxy-PEG1-CH2-Boc 287174-32-7 tert-Butyl 2-(2-hydroxyethoxy)acetate is a linker.
CSN23939 Cl-C6-PEG4-O-CH2COOH 1799506-30-1 PROTAC Linker 4 is a linker used to link the warhead and the E3 ligase ligand.
CSN23938 Boc-C5-O-C5-O-C6-Cl 1835705-52-6 PROTAC Linker 2 is a linker used to link the warhead and the E3 ligase ligand.
CSN22492 Boc-C1-PEG2-C4-Cl 1835705-53-7 PROTAC Linker 1 is a linker used to link the warhead and the E3 ligase ligand.
CSN32773 tert-Butyl (2-(prop-2-yn-1-yloxy)ethyl)carbamate 634926-63-9 O-Proparagyl-N-Boc-ethanolamine is a linker.
CSN27332 NH2-PEG2-C2-Boc 756525-95-8 NH2-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. NH2-PEG2-C2-Boc is also a non-cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CSN22200 N33-TEG-COOH 201467-81-4 N33-TEG-COOH is a linker used to link the warhead and the E3 ligase ligand.
CSN26836 N-Bromoacetyl-β-alanine 89520-11-6 N-Bromoacetyl-β-alanine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-Bromoacetyl-β-alanine is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].
CSN29105 m-PEG6-Amine 184357-46-8 m-PEG6-amine is a PEG derived linker containing an amino group.
CSN27310 m-PEG4-Br 110429-45-3 m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab (HY-P9907). m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency.
CSN23896 Bromo-PEG3-azide 1446282-43-4 Bromo-PEG3-azide is a PEG-derived linker containing a bromide group and a terminal azide.
CSN27331 Boc-NH-PEG4-CH2CH2COOH 756525-91-4 Boc-NH-PEG4-CH2CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTAC. Boc-NH-PEG4-CH2CH2COOH is also a cleavable ADC linker used as a linker for antibody-drug conjugates (ADC).
CSN27311 Bis-PEG8-acid 1246189-43-4 Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CSN23920 Bis-PEG4-acid 31127-85-2 Bis-PEG4-acid is a linker used to link the warhead and the E3 ligase ligand.
CSN27354 Amino-PEG4-alcohol 86770-74-3 Amino-PEG4-alcohol is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Amino-PEG4-alcohol is also a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
CSN22277 CH2COOH-PEG3-CH2COOH 32775-08-9 A PEG linker for PROTAC.
CSN32763 3-(2-Iodoethoxy)prop-1-yne 164118-56-3 3-(2-Iodoethoxy)prop-1-yne is a linker.
CSN32748 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethanol 131326-39-1 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethanol is a linker.
CSN32751 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-amine 215297-17-9 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)ethan-1-amine is a linker.
CSN32756 Tos-PEG2-NH-Boc 192132-77-7 2-(2-((tert-Butoxycarbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate is a linker.
CSN32757 2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate 144208-62-8 2-(2-(((Benzyloxy)carbonyl)amino)ethoxy)ethyl 4-methylbenzenesulfonate is a linker.
CSN32761 2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate 1858242-47-3 2,5-Dioxopyrrolidin-1-yl 2-(prop-2-yn-1-yloxy)acetate is a linker.
CSN32749 Aminooxy-PEG2-alcohol 185022-12-2
CSN32765 Bromo-PEG1-CH2-Boc 157759-50-7
CSN32768 Aminooxy-PEG1-propargyl 1895922-69-6
CSN32754 2-(2-((tert-Butyldimethylsilyl)oxy)ethoxy)acetic acid 909282-26-4
CSN32769 Benzyl (2-(2-aminoethoxy)ethyl)carbamate 1290627-95-0
CSN32770 2-(But-3-yn-1-yloxy)ethanamine 122116-14-7
CSN32762 2-(Prop-2-ynyloxy)acetic acid 98021-61-5
CSN32771 NH2-PEG1-C1-Boc 1155811-37-2
CSN32752 Hydroxy-PEG1-methylamine 85475-01-0
CSN32758 Propargyl-PEG2-Tos 145916-41-2
CSN32764 4-(2-Bromoethoxy)but-1-yne 854259-74-8
CSN32760 2-(Prop-2-yn-1-yloxy)acetaldehyde 801294-16-6
CSN32772 tert-Butyl N-{2-[2-(methylamino)ethoxy]ethyl}carbamate 1185772-28-4
CSN32766 tert-Butyl 2-(2-iodoethoxy)acetate 1401351-72-1
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