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RAR/RXR
货号 | 产品名 | CAS号 | 信息 |
---|---|---|---|
CSN10273 | 4-((5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbamoyl)benzoic acid | 94497-51-5 | Tamibarotene is an agonist of retinoic acid receptor α (RARα) with ED50 of 0.79 nM that can induce differentiation and apoptosis of HL-60 cells. |
CSN12480 | 6-(3-(Adamantan-1-yl)-4-methoxyphenyl)-2-naphthoic acid | 106685-40-9 | Adapalene is an agonist of RAR-β (Kd = 34 nM), RAR-γ (Kd = 130 nM) and RXR which is used in the treatment of acne. |
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