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Antibacterial
| 货号 | 产品名 | CAS号 | 信息 |
|---|---|---|---|
| CSN26514 | Xinjiachalcone A | 151410-32-1 | Xinjiachalcone A is an active principle of Glycyrrhiza inflata Batalin. Xinjiachalcone A shows both a low MIC and a strong bactericidal activity against H. pylori, with MIC values ranged from 12.5 to 50 µM for seventeen H. pylori strains[1]. |
| CSN24627 | Viomycin | 32988-50-4 | Viomycin is a member of the tuberactinomycin family of antibiotics. It can inhibit group I intron splicing and prokaryotic protein synthesis. |
| CSN26391 | Valinomycin | 2001-95-8 | Valinomycin, a cyclic depsipeptide antibiotic first isolated from Streptomyces fulvissimus, act as a potassium selective ionophore. Valinomycin inhibits lymphocyte proliferation by its effects on the cell membrane, and induces apoptosis in CHO cells[1]. Valinomycin induces activation of PINK1 leading to Parkin Ser65 phosphorylation[2]. |
| CSN24708 | Tyrphostin AG30 | 122520-79-0 | Tyrphostin AG 30 is an antimicrobial peptide with angiogenic properties. It activates human mast cells through the MAPK and NF-κB pathways. |
| CSN24630 | Trovafloxacin mesylate | 147059-75-4 | Trovafloxacin is a broad spectrum antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC50 = 3.02 µg/ml) and DNA gyrase (IC50 = 7.13 µg/ml). |
| CSN21859 | Tigemonam | 102507-71-1 | Tigemonam is a monobactam, with potent activity against Gram-negative aerobic bacterial pathogens. |
| CSN32894 | (4R,5S,6S)-(Pivaloyloxy)methyl 3-((1-(4,5-dihydrothiazol-2-yl)azetidin-3-yl)thio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate hydrobromide | 1381788-20-0 | Tebipenem pivoxil hydrobromide is a PBP inhibitor. |
| CSN42287 | Surfactin C1 | 24730-31-2 | Surfactin is an excellent biosurfactant with a wide range of application prospects in many industrial fields. |
| CSN33126 | Sulopenem | 120788-07-0 | Sulopenem is an orally active, parenteral penem antibiotic with broad-spectrum activities against Gram-positive and Gram-negative bacteria. |
| CSN21845 | Sulfaproxiline | 116-42-7 | Sulfaproxyline is a synthetic antimicrobial drug that is sulfonamide. |
| CSN22041 | Sulfabrom | 116-45-0 | Sulfabrom is a long-acting veterinary medicine that is used for the treatment of coccidiosis and various bacterial infections in the poultry, swine and cattle. |
| CSN24116 | Sodium benzoate | 532-32-1 | Sodium benzoate is a preservative and uesd as a food additive which is bacteriostatic and fungistatic under acidic conditions |
| CSN26531 | Sandramycin | 100940-65-6 | Sandramycin ia a cyclic depsipeptide antibiotic isolated from cultured broth of a Nocardioides sp. Sandramycin is also a DNA intercalator that potently binds DNA and is an ADC cytotoxin. Sandramycin is active against Gram-positive bacteria and has potent antitumor activity[1][2][3]. |
| CSN24749 | Qstatin | 902688-24-8 | Qstatin is a potent and selective inhibitor of Vibrio quorum sensing (QS). SmcR is the LuxR homologue in V. vulnificus. |
| CSN26537 | 3-Chloro-4-(3-chloro-2-nitrophenyl)-1H-pyrrole | 1018-71-9 | Pyrrolnitrin is an antibiotic isolated from Pseudomonas pyrrocinia. Pyrrolnitrin shows a broad spectrum of antibiotic activity against fungi, yeast and gram-positive bacteria[1]. |
| CSN28509 | Protactin | 141912-59-6 | Protactin is a new antibiotic metabolite and a possible precursor of the actinomycins. |
| CSN33140 | Plazomicin | 1154757-24-0 | Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin demonstrates high activity against the Enterobacteriaceae including extended spectrum beta lactamase and most carbapenemase producers, and can be useful in treating complicated urinary tract infections (cUTIs) and acute pyelonephritis. |
| CSN11714 | Phytol | 150-86-7 | Phytol can activite PPARα and attenuate the inflammatory response by inhibiting neutrophil migration and oxidative stress. Phytol is isolated from the leaves of black tea and acts as an aromatic ingredient. |
| CSN26585 | Oxazosulfyl | 1616678-32-0 | Oxazosulfyl is a potent agricultural fungicide. Oxazosulfyl can be used as an insecticide against major rice pests[1]. |
| CSN21752 | Framycetin | 119-04-0 | Neomycin B is an aminoglycoside antibiotic that can inhibit hammerhead ribozyme with a Ki of 13.5 μM. |
| CSN15108 | Neochamaejasmin B | 90411-12-4 | Neochamaejasmine B, a natural product isolated and purified from the roots of Stellera chamaejasme Linn. with antibacterial activity on Gram-positive bacterium and Gram-negative bacterium, displays nematicidal activity against both Bursaphelenchus xylophilus and Bursaphelenchus mucronatus, and reduces seedling growth and disrupt root development, the IC50 value of 6.9 ug/mL. |
| CSN26589 | Op-0595 | 1452458-86-4 | Nacubactam, also known as RG-6080, FPI-1459, and OP-0595, is a beta-lactamase inhibitor used for treating bacterial infections. |
| CSN15161 | Moracin C | 69120-06-5 | Moracin C, a natural product isolated and purified from the root bark of Morus alba L., is a potent antibacterial compound which inhibits FabI and fatty acid synthesis. |
| CSN21737 | Monobehenin | 30233-64-8 | Monobehenin can inhibit bacterial biofilm formation. |
| CSN21721 | Magainin 1 | 108433-99-4 | Magainin is a 23-residue peptide and naturally found on the skin of african clawed frog. It has a broad spectrum specificity towards many gram-negative bacteria. |
| CSN21722 | Magainin 2 | 108433-95-0 | Magainin II, an antibiotic in a variety of organisms, can bind to anionic phospholipids abundant in bacterial membranes and also exhibit cytotoxic. |
| CSN19899 | Nevadensin | 10176-66-6 | Lysionotin is a natural product isolated and purified from the lysionotius pauciflorus maxim and can be used for bacterial infections. |
| CSN24629 | LF11 | 832729-13-2 | LF 11 is peptide based on the lipopolysaccharide (LPS)-binding region of human lactoferricin. It can neutralize LPS with antimicrobial activity against bacteria. |
| CSN14025 | Kumatakenin | 3301-49-3 | Kumatakenin, a natural product isolated and purified from the roots of Astragalus membranaceus, has antibacterial and antifungal activities. |
| CSN24747 | 4-Chloro-N-(5-(4-fluorophenyl)-1,3,4-oxadiazol-2-yl)benzamide | 865285-29-6 | KKL-35, a potent member of the oxadiazole family, against the human pathogen Legionella pneumophila and other related species that can also cause Legionnaires' disease. |
| CSN26437 | Kasugamycin hydrochloride | 19408-46-9 | Kasugamycin hydrochloride is an antibiotic which binds both the 30S and 70S ribosome but not isolated 50S subunits. Kasugamycin hydrochloride mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. |
| CSN21688 | Indolicidin | 140896-21-5 | Indolicidin, a 13-residue cationic antimicrobial peptide-amide isolated from the cytoplasmic granules of bovine neutrophils. It is a member of the cathelicidin protein family. |
| CSN10009 | Hordenine | 539-15-1 | Hordenine is a naturally occuring phenylethylamine alkaloid isolated from the herbs of Dendrolobium triangulare with antibacterial and antibiotic effect. |
| CSN11140 | Hederagenin | 465-99-6 | Hederagenin is a plant metabolite which can prevent fungal growth, bacterial growth, and viral plant diseases. |
| CSN14558 | Haplopine | 5876-17-5 | Haplopine, a natural product isolated and purified from the fruits of Zanthoxylum bungeanum Maxim, shows photo-activated antimicrobial activity against S. aureus and exhibits potent melanogenesis-inhibitory activities with almost no toxicity to the cells. |
| CSN22002 | H-Lys-Trp-Lys-OH | 38579-27-0 | H-Lys-Trp-Lys-OH is a small molecule peptide which displays antibacterial and antiviral activities extracted from patent CN 104072579 A, Compound AMP12. |
| CSN21660 | Gramicidin | 1405-97-6 | Gramicidin is a polypeptide antibiotic mixture of gramicidin A, gramicidin B, and gramicidin C originally isolated from B. brevis. |
| CSN11098 | Ginkgolic Acid (C13:0) | 20261-38-5 | Ginkgolic Acid C13:0 is a natural product with wide antimicrobial spectrum. |
| CSN15170 | Gancaonin I | 126716-36-7 | Gancaonin I is a natural product isolated and purified from the roots of Glycyrrhiza glabra with anti-BsFtsZ GTPase activities and significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. |
| CSN19996 | 3-O-Methylgalangin | 6665-74-3 | Galangin-3-methyl ether is a natural product isolated and purified from the rhizomes of Alpinia officinarum Hance with antibacterial activity agansit Pseudomonas aeruginosa and hypolipidemic activity due to the inhibition of pancretic lipase. |
| CSN26584 | (S)-3-(Aminomethyl)-4-chloro-7-(2-hydroxyethoxy)benzo[c][1,2]oxaborol-1(3H)-ol hydrochloride | 2131798-13-3 | for human mitochondrial LeuRS and human cytoplasmic LeuRS, respectively. In addition, it exhibits remarkable PK profiles and efficacy against Mtb in mouse TB infection models with superior tolerability over initial leads. GSK656 has been progressed to clinical development for the treatment of tuberculosis. |
| CSN21645 | Fibracillin | 51154-48-4 | Fibracillin is a penicillin antibiotic. |
| CSN22015 | DuP 105 | 96800-41-8 | DuP 105 is an orally active oxazolidinone, a new class of synthetic antimicrobial agent with activity against gram-positive bacteria. |
| CSN26588 | 1-Cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid hydrochloride | 93107-08-5 | Ciprofloxacin hydrochloride is a broad-spectrum antimicrobial carboxyfluoroquinoline, an fluoroquinolone antibiotic that is widely used as an antimicrobial and immunomodulatory agent. It is capable of inducing respiratory, urinary tract, gastrointestinal, and abdominal infections. It functions by inhibiting DNA gyrase (a type II topoisomerase) and topoisomerase IV, the enzymes responsible for negative supercoiling of chromosomes and DNA strand separation, thus blocking initiation of bacterial replication. Most recently ciprofloxacin has been used in the management of postexposure inhalational anthrax and radiation combined injury resulting from nuclear disasters. |
| CSN26433 | Ceftazidime pentahydrate | 78439-06-2 | Ceftazidime pentahydrate is a third generation cephalosporin administered intravenously or intramuscularly. Ceftazidime pentahydrate has a broad spectrum of in vitro activity against Gram-positive and Gram-negative aerobic bacteria. Ceftazidime pentahydrate is particularly active against Enterobacteriaceae (including beta-lactamase-positive strains) and is resistant to hydrolysis by most beta-lactamases[1]. |
| CSN32892 | (4R,5S,6S)-6-((R)-1-Hydroxyethyl)-4-methyl-7-oxo-3-(((3S,5S)-5-((4-sulfamoylbenzyl)carbamoyl)pyrrolidin-3-yl)thio)-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid | 1312953-83-5 | Benapenem is a PBP inhibitor. |
| CSN33259 | (2S,2a'E,2a1'S,4'E,5S,6R,6'S,7'S,8'E,11'R,15'S,17a'R,20'R,20a'R)-2a1',20'-dihydroxy-7'-(((2R,4S,5S,6S)-5-(((2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6-isopropyl-5,6',8',19'-tetramethyl-2a1',5,6,6',7',10',11',14',15',17a',20',20a'-dodecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one and (2S,2a'E,2a1'S,4'E,5S,6R,6'S,7'S,8'E,11'R,15'S,17a'R,20'R,20a'R)-6-((S)-sec-butyl)-2a1',20'-dihydroxy-7'-(((2R,4S,5S,6S)-5-(((2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-4-methoxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-5,6',8',19'-tetramethyl-2a1',5,6,6',7',10',11',14',15',17a',20',20a'-dodecahydro-2'H,17'H-spiro[pyran-2,13'-[11,15]methano[1,5]dioxacyclooctadecino[9,8,7-cd]benzofuran]-17'-one | 71751-41-2 | Abamectin is composed of avermectin B1a and avermectin B1b, which are macrocyclic lactone compounds. |
| CSN34621 | 6-Amino-5-azacytidine | 105331-00-8 | 6-Amino-5-azacytidine inhibits the growth of bacteria E. coli. |
| CSN27115 | 9-((3aR,4R,6R,6aR)-6-(Hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-ol | 2140-11-6 |
